Results 81 to 90 of about 173,869 (207)

A moderate inflammation caused by the deterioration of housing conditions modifies Trp metabolism but not Trp requirement for growth of post-weaned piglets

Animal, 2010
Deterioration of the environment in which piglets are housed after weaning induces a moderate inflammatory response and modifies tryptophan (Trp) metabolism that can, in turn, decrease Trp availability for growth.
N. Le Floc’h, J.J. Matte, D. Melchior, J. van Milgen, B. Sève   +4 more
doaj   +1 more source

Structure−Activity Relationships of the Melanocortin Tetrapeptide Ac-His-DPhe-Arg-Trp-NH₂ at the Mouse Melanocortin Receptors:  Part 2 Modifications at the Phe Position

, 2016
The melanocortin pathway is an important participant in skin pigmentation, steroidogenesis, obesity, energy homeostasis and exocrine gland function.
Jerry Ryan Holder (2401027), Rayna M. Bauzo (2684014), Zhimin Xiang (2719438), Carrie Haskell-Luevano (1322436)   +3 more
core   +1 more source

Task optimized vision transformer for diabetic retinopathy detection and classification in resource constrained early diagnosis settings

Scientific Reports
Diabetic Retinopathy (DR) is a progressive complication of diabetes and a leading cause of preventable blindness worldwide. Early detection and accurate classification of DR severity are critical for timely intervention but remain challenging ...
Ramasubramanian Bhoopalan, Priyadharshini Sekar, N. Nagaprasad, Tadesse Regassa Mamo, Ramaswamy Krishnaraj   +4 more
doaj   +1 more source

d-Trp in site 1.

, 2016
Left: Part of the electron density map in site 2 with d-Trp bound. The model conformation for the α2bβ3-loop is in good agreement with the map (2Fo-Fc map contoured at 1.0 σ (blue mesh) and Fo-Fc omit map contoured at 3.0 σ (green mesh)).
Nicola J. Blackmore (2634682), Sebastian Reichau (2181230), Emily J. Parker (1397425), Wanting Jiao (1883032)   +3 more
core   +1 more source

Sulfoxide-mediated Cys-Trp-selective bioconjugation that enables protein labeling and peptide heterodimerization [PDF]

A method was developed that enables the magnesium chloride (MgCl2)-activated S-acetamidomethyl cysteine sulfoxide (Cys(Acm)(O)) to induce the sp2(C−H) sulfenylation of the indole ring of Trp residues.
Kota, Hidaka, Harunori, Yoshikawa, Kento, Ohkawachi, Hidetaka, Kosako, Akira, Otaka, Wataru, Nomura, Kohei, Nishino, Tetsuro, Yoshimaru, Daishiro, Kobayashi, Junya, Hayashi, Kiyomi, Nigorikawa, Masaya, Deda, Yutaka, Kohmura, Naozumi, Ishimaru, Toyomasa, Katagiri, Takaaki, Tsunematsu   +15 more
core   +2 more sources

Microbial modulation of tryptophan metabolism links gut microbiota to disease and its treatment

Pharmacological Research
Emerging studies have demonstrated that tryptophan (Trp) metabolism plays a critical role in maintaining intestinal and systemic homeostasis. Trp metabolism is involved in diseases such as metabolic syndrome, gastrointestinal cancers, neurological ...
Pengfei Zhao, Yuqi Chen, Shuyu Zhou, Fei Li   +3 more
doaj   +1 more source

Another TRP to endothelial dysfunction [PDF]

, 2008
Gudermann, Thomas, Dietrich, Alexander
core   +1 more source

Fertility and TRP Channels

, 2018
Since their discovery in late 1970, transient receptor potential (TRP) channels have been implicated in a variety of cellular and physiological functions (Minke, 2010). The superfamily of TRP channels consists of nearly 30 members that are organized into
Lishko, Polina V, Bjorkgren, Ida
core   +1 more source

TRPs in bladder diseases

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2007
This review attempts to provide an overview of the current knowledge of TRP proteins and their possible role in bladder function and disease. At present, there are 28 transient receptor potential (TRP) channels (subdivided into 7 categories or families) which are involved in a number of functions [G.A.
openaire   +3 more sources

Effect of Tryptophan Supplementation Levels on the Cecal Microbial Composition, Growth Performance, Immune Function and Antioxidant Capacity in Broilers

Metabolites
Background: Tryptophan (Trp) is a limiting amino acid in poultry nutrition. Dietary supplementation of Trp not only enhances production performance, but also supports intestinal barrier integrity, alleviates stress, and boosts immunity, in which the ...
Xuelan Liu, Chunyan Fu, Qingtao Gao, Heng Zhang, Tianhong Shi, Guiming Li, Yunchao Wang, Yan Shang   +7 more
doaj   +1 more source