Results 101 to 110 of about 173,869 (207)

Reconstitution of lysosomal NAADP-TRP-ML1 signaling pathway and its function in TRP-ML1−/−cells

open access: yes, 2011
It is well known that the mutation of TRP-ML1 (transient receptor potential-mucolipin-1) causes mucolipidosis IV, a lysosomal storage disease. Given that lysosomal nicotinic acid adenine dinucleotide phosphate (NAADP)-Ca2+release channel activity is ...
Ming Xu   +3 more
core   +1 more source

Assessment of pneumonitis in patients with lung cancer undergoing radioimmunotherapy and immune checkpoint inhibitor rechallenge

open access: yesCommunications Medicine
Background: The combination of immune checkpoint inhibitors (ICIs) with radiotherapy (RT) has improved survival in patients with advanced lung cancer, yet treatment-related pneumonitis (TRP) is highly toxic.
Yingchen Ruan   +10 more
doaj   +1 more source

Tryptophan Metabolism in Digestive and Extra-Digestive Diseases: Mechanisms, Clinical Implications, and Therapeutic Perspectives. [PDF]

open access: yesNutrients
Tohumcu E   +13 more
europepmc   +1 more source

Cathepsin B-Activatable Bioactive Peptide Nanocarrier for High-Efficiency Immunotherapy of Asthma

open access: yesInternational Journal of Nanomedicine
Taiyu Song,* Lulu Yao,* Angang Zhu,* Guangling Liu, Beibei Zhu, Qian Zhao, Yue Zhao, Jinya Wang Department of Pediatrics, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, People’s Republic of ...
Song T   +7 more
doaj  

Transition-Relevance Place (TRP)

open access: yes
The notion of a transition-relevance place (TRP) was introduced by Sacks, Schegloff and Jefferson (1974) to explain how a current speaker and a next speaker coordinate turn-transitions in an orderly manner.
Shimako Iwasaki
core   +1 more source

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