Reconstitution of lysosomal NAADP-TRP-ML1 signaling pathway and its function in TRP-ML1−/−cells
It is well known that the mutation of TRP-ML1 (transient receptor potential-mucolipin-1) causes mucolipidosis IV, a lysosomal storage disease. Given that lysosomal nicotinic acid adenine dinucleotide phosphate (NAADP)-Ca2+release channel activity is ...
Ming Xu +3 more
core +1 more source
Background: The combination of immune checkpoint inhibitors (ICIs) with radiotherapy (RT) has improved survival in patients with advanced lung cancer, yet treatment-related pneumonitis (TRP) is highly toxic.
Yingchen Ruan +10 more
doaj +1 more source
Tryptophan Metabolism in Digestive and Extra-Digestive Diseases: Mechanisms, Clinical Implications, and Therapeutic Perspectives. [PDF]
Tohumcu E +13 more
europepmc +1 more source
Cathepsin B-Activatable Bioactive Peptide Nanocarrier for High-Efficiency Immunotherapy of Asthma
Taiyu Song,* Lulu Yao,* Angang Zhu,* Guangling Liu, Beibei Zhu, Qian Zhao, Yue Zhao, Jinya Wang Department of Pediatrics, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, People’s Republic of ...
Song T +7 more
doaj
Methods for storage and determination of tryptophan and serotonin in bovine blood by high-performance liquid chromatography with fluorescence detection. [PDF]
Markmann RC +7 more
europepmc +1 more source
Transition-Relevance Place (TRP)
The notion of a transition-relevance place (TRP) was introduced by Sacks, Schegloff and Jefferson (1974) to explain how a current speaker and a next speaker coordinate turn-transitions in an orderly manner.
Shimako Iwasaki
core +1 more source
From Bibliometrics to Preliminary Clinical Evidence: TRP Channel-Mediated Neuroimmune Crosstalk in Temperature-Sensitive Airway Hyperresponsiveness. [PDF]
Wang Y +11 more
europepmc +1 more source
Tryptophan Supplementation Reduces Schizophrenia-Like Symptoms in Apomorphine Treated Rats: Role of D2, GABA, and Glutamate Receptor Expression. [PDF]
Nawaz S +5 more
europepmc +1 more source
The gut microbiota-tryptophan metabolism-immune axis in inflammatory bowel disease: Mechanisms and therapeutic prospects. [PDF]
Wang T, Wang X, Yuan W.
europepmc +1 more source
Serotonin neuromicrobiology: Psychobiotic modulation of the gut-brain axis for mental health. [PDF]
Mandloi N +4 more
europepmc +1 more source

