Results 31 to 40 of about 6,247 (194)
Frontiers in Surgery, 2022 BackgroundTransient receptor potential channel 1 (TRPC1) regulates the progression of several cancers, but its clinical implication in renal cell carcinoma (RCC) has not been explored yet.
Liang Chen +4 more
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Pharmacological Research, 2022 Cardiac dysfunction is a vital complication of endotoxemia (ETM) with limited therapeutic options. Transient receptor potential canonical channel (TRPC)1 was involved in various heart diseases.
Wen Tian +10 more
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The dynamic complexity of the TRPC1 channelosome [PDF]
Channels, 2011 A rise in cytoplasmic [Ca2+] due to store-operated Ca2+ entry (SOCE) triggers a plethora of responses, both acute and long term. This leads to the important question of how this initial signal is decoded to regulate specific cellular functions. It is now clearly established that local [Ca2+] at the site of SOCE can vary significantly from the global ...
Hwei Ling, Ong, Indu S, Ambudkar
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Pharmaceutical Biology, 2023 Context Salvia miltiorrhizae Bunge (Lamiaceae) is a traditional Chinese medicine (TCM) for the treatment of ‘thoracic obstruction’. Transient receptor potential canonical channel 1 (TRPC1) is a important target for myocardial injury treatment.Objective ...
Wei Quan +10 more
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, 2022 Data for TRPC1 signal restricted to the plasma ...
Declan Manning (13171413)
core +1 more source
Expression of trpC1 and trpC6 orthologs in zebrafish [PDF]
Gene Expression Patterns, 2008 Transient receptor potential (TRP) genes encode subunits that form cation-selective ion channels in a variety of organisms and cell types. TRP channels serve diverse functions ranging from thermal, tactile, taste, and osmolar sensing to fluid flow sensing.
Clemens C, Möller +3 more
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Oncogenesis, 2021 Transient receptor potential canonical (TRPC) channels are the most prominent nonselective cation channels involved in various diseases. However, the function, clinical significance, and molecular mechanism of TRPCs in colorectal cancer (CRC) progression
Yang Sun +10 more
doaj +1 more source
Dual action of the Gαq-PLCβ-PI(4,5)P2 pathway on TRPC1/4 and TRPC1/5 heterotetramers [PDF]
Scientific Reports, 2018 AbstractThe transient receptor potential canonical (TRPC) 1 channel is widely distributed in mammalian cells and is involved in many physiological processes. TRPC1 is primarily considered a regulatory subunit that forms heterotetrameric channels with either TRPC4 or TRPC5 subunits.
Jongyun Myeong +10 more
openaire +2 more sources
Local Ca²+ entry via Orai1 regulates plasma membrane recruitment of TRPC1 and controls cytosolic Ca²+ signals required for specific cell functions. [PDF]
PLoS Biology, 2011 Store-operated Ca²+ entry (SOCE) has been associated with two types of channels: CRAC channels that require Orai1 and STIM1 and SOC channels that involve TRPC1, Orai1, and STIM1.
Kwong Tai Cheng +4 more
doaj +1 more source