Frontiers in Physiology, 2017 Tooth development depends on multiple molecular interactions between the dental epithelium and mesenchyme, which are derived from ectodermal and ectomesenchymal cells, respectively.
Jun Yang +4 more
doaj +1 more source
A diacylglycerol photoswitching protocol for studying TRPC channel functions in mammalian cells and tissue slices. [PDF]
STAR Protoc, 2021 Leinders-Zufall T +6 more
europepmc +1 more source
Activation of TRPC (Transient Receptor Potential Canonical) Channel Currents in Iron Overloaded Cardiac Myocytes. [PDF]
Circ Arrhythm Electrophysiol, 2021 Siri-Angkul N +7 more
europepmc +1 more source
DAG-sensitive and Ca(2+) permeable TRPC6 channels are expressed in dentate granule cells and interneurons in the hippocampal formation [PDF]
, 2013 Members of the transient receptor potential (TRP) cation channel family play important roles in several neuronal functions. To understand the precise role of these channels in information processing, their presence on neuronal elements must be revealed ...
Borhegyi, Zsolt +5 more
core +1 more source
Frontiers in Pharmacology, 2016 In the murine brain, the first post-mitotic cortical neurons formed during embryogenesis express store-operated channels (SOCs) sensitive to Pyr3, initially proposed as a blocker of transient receptor potential channel of C type 3 (TRPC3 channel ...
Sylvain Chauvet +5 more
doaj +1 more source
Differential expression and hypoxic regulation of adenosine receptors and TRPC channels in the developing heart. [PDF]
, 2012 Objectives: To characterize the modifications of gene expression of adenosine receptors (AR), TRPC channels, HIF-1α and iNOS during the early cardiogenesis in response to chronic hypoxia exposure. Methods: 4-day-old chick embryos were subjected in ovo to
Carrupt, M.
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Molecular Determinants of the Sensitivity to Gq/11-Phospholipase C-dependent Gating, Gd3+ Potentiation, and Ca2+ Permeability in the Transient Receptor Potential Canonical Type 5 (TRPC5) Channel [PDF]
, 2016 Transient receptor potential canonical type 5 (TRPC5) is a Ca2+-permeable cation channel that is highly expressed in the brain and is implicated in motor coordination, innate fear behavior, and seizure genesis.
Chakraborty, Saikat Chakrabort +6 more
core +1 more source
TRP Channels: Current Perspectives in the Adverse Cardiac Remodeling [PDF]
, 2019 Calcium is an important second messenger required not only for the excitation-contraction coupling of the heart but also critical for the activation of cell signaling pathways involved in the adverse cardiac remodeling and consequently for the heart ...
Calderón Sánchez, Eva María +7 more
core +1 more source
Pharmacological Properties of Novel TRPC Channel Inhibitors
YAKUGAKU ZASSHI, 2010 Ca(2+) signals control diverse cellular processes, ranging from ubiquitous activities like gene expression to tissue specific responses such as lymphocyte activation and cardiac diseases. TRPC channels control Ca(2+) influxes that induce diverse cellular processes upon stimulation of plasma membrane receptors coupled to phospholipase C (PLC). Invention
Kiyonaka, Shigeki +3 more
openaire +3 more sources
Homer/vesl proteins and their roles in CNS neurons [PDF]
, 2018 Since their initial discovery in 1997, Homer/Vesl proteins have become increasingly investigated as putative regulators of receptor and ion-channel function in the central nervous system.
Ehrengruber, Markus +3 more
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