Results 101 to 110 of about 1,209,942 (198)

Sildenafil decreases rat tracheal hyperresponsiveness to carbachol and changes canonical transient receptor potential gene expression after antigen challenge

open access: yesBrazilian Journal of Medical and Biological Research, 2011
Inhibition of type-5 phosphodiesterase by sildenafil decreases capacitative Ca2+ entry mediated by transient receptor potential proteins (TRPs) in the pulmonary artery.
C.T. Sousa   +7 more
doaj   +2 more sources

CaR-mediated vasodilatation: Role of endothelium TRPC channels

open access: yes, 2012
There is increasing evidence that Ca2+-sensing G-protein-coupled receptors (CaR) have an important role in modulating vascular activity; both CaR-mediated contraction and dilation responses have been proposed.
Greenwood, Iain A.   +6 more
core   +1 more source

Investigation of TRPC channels in health and disease in cerebellum

open access: yes, 2008
In the brain, classical (canonical) transient receptor potential (TRPC) channels are thought to be involved in different aspects of neuronal development.
Huang, Wan Chen
core  

A key role of TRPC channels in the regulation of electromechanical activity of the developing heart

open access: yes, 2011
Aims It is well established that dysfunction of voltage-dependent ion channels results in arrhythmias and conduction disturbances in the foetal and adult heart.
Elodie Robin   +5 more
core   +1 more source

Targeting TRPC Channels for Control of Arthritis-Induced Bone Erosion

open access: yes
Arthritis leads to bone erosion due to an imbalance between osteoclast and osteoblast function. Our prior investigations revealed that the Ca2+-selective ion channel, Orai1, is critical for osteoclast maturation. Here, we show that the small-molecule ELP-
Groschner, Klaus   +16 more
core   +1 more source

A key role of TRPC channels in the regulation of electromechanical activity of the developing heart [PDF]

open access: yes, 2017
Aims It is well established that dysfunction of voltage-dependent ion channels results in arrhythmias and conduction disturbances in the foetal and adult heart.
Raddatz, Eric   +2 more
core  

TRPC Channels—Insight from the Drosophila Light Sensitive Channels

open access: yes, 2018
The Drosophila Transient Receptor Potential (TRP) channel is the founding member of a large and diverse family of channel proteins. These channels are evolutionarily conserved from yeast to mammals and are found in many organisms and tissues.
Baruch Minke, William L. Pak, Ben Katz
core   +1 more source

Cooperative strategies in the UWB TRPC networks

open access: yes, 2011
Transmitted reference pulse cluster (TRPC) was recently proposed for ultrawideband (UWB) communications attributing to its robust performance, higher data rate, enhanced reliability and lower implementation complexity compared with the conventional ...
Dong, Xue
core  

Echinacoside inhibits PASMCs calcium overload to prevent hypoxic pulmonary artery remodeling by regulating TRPC1/4/6 and calmodulin

open access: yesOpen Medicine
ECH was observed to inhibit [Ca2+]cyt increase in NE-induced PASMCs in a concentration-dependent manner, effectively reducing abnormal cell proliferation.
Zhao Enqi   +7 more
doaj   +1 more source

Understanding the key drivers of and technology related issues associated with going multi-channel [PDF]

open access: yes, 2012
A multi-channel retail strategy is viewed by many academics and practitioners to be the success model for most retailers. Yet, while there are many drivers of, and advantages related to, using multiple channels to sell products and services to customers ...
Whysall, P   +5 more
core  

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