Results 81 to 90 of about 1,209,942 (198)
Molecular Plant Pathology, Volume 27, Issue 8, August 2026.AaVCX, a vacuolar Ca2+/H+ exchanger regulated by AaCrz1, maintains calcium homeostasis. Its deletion elevates cytoplasmic Ca2+, disrupting signals essential for spore germination, appressorium formation and infection hyphae differentiation, thereby blocking infection structure differentiation and reducing pathogenicity in Alternaria alternata ...
Yangyang Yang +7 more
wiley +1 more source
Novel Targets for Stroke Therapy: Special Focus on TRPC Channels and TRPC6
Frontiers in Aging Neuroscience, 2020 Stroke remains a leading cause of death, disability, and medical care burden worldwide. However, transformation from laboratory findings toward effective pharmacological interventions for clinical stroke has been unsatisfactory.
Lu Liu +6 more
doaj +1 more source
Plant, Cell &Environment, Volume 49, Issue 8, Page 5703-5719, August 2026.ABSTRACT Salinity stress disrupts rhizosphere homoeostasis and inhibits root development. Although PGPR are known to alleviate such stress, critical knowledge gaps remain regarding the specific mechanisms by which they enhance tolerance under moderate to high salinity, particularly within the wheat rhizosphere ‐root interface.
Fuqiang Zhu +10 more
wiley +1 more source
Kv7 and Kv11 channels in myometrial regulation. [PDF]
, 2013 Ion channels play a key role in defining myometrial contractility. Modulation of ion channel populations is proposed to underpin gestational changes in uterine contractility associated with the transition from uterine quiescence to active labour.
Tribe, Rachel M; id_orcid +5 more
core +1 more source
Optimization of photobiomodulation therapy for spinal cord injury: A review
Photochemistry and Photobiology, Volume 102, Issue 4, Page 797-831, July/August 2026.Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew +3 more
wiley +1 more source
Determining the functional role of TRPC channels in primary cells.
, 2005 Although the TRPC members of the mammalian transient receptor potential TRP cation channel family were the first to be described in 1995, the depth of knowledge of TRPC channels has fallen behind that of their counterparts in the TRPV and TRPM ...
Su Li (294188) +5 more
core +1 more source
TRPC channels are not required for graded persistent activity in entorhinal cortex neurons [PDF]
, 2019 : Adaptive behavior requires the transient storage of information beyond the physical presence of external stimuli. This short-lasting form of memory involves sustained ("persistent") neuronal firing which may be generated by cell-autonomous biophysical ...
Rebekka Medert +11 more
core +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.This study reveals that 5‐hydroxytryptamine (5‐HT) synapses in the spinal cord and 5‐HT neurons in the brainstem of the SOD1‐G93A amyotrophic lateral sclerosis (ALS) mouse model are significantly altered, showing a decrease in pre‐symptomatic stages but a marked increase as the disease progresses.
Lijun Zhou +7 more
wiley +1 more source
Journal of Pharmacological Sciences, 2008 Ca2+ is a pivotal signal in human pulmonary artery smooth muscle cells (PASMCs) proliferation. Capacitative Ca2+ entry (CCE) via the store-operated channel (SOC), which encoded by the transient receptor potential (TRP) gene, is an important mechanism for
Cong Wang +7 more
doaj +1 more source
Nonselective TRPC channel inhibition and suppression of aminoglycoside-induced premature termination codon readthrough by the small molecule AC1903. [PDF]
J Biol Chem, 2022 Baradaran-Heravi A +9 more
europepmc +1 more source