Results 131 to 140 of about 802,895 (179)

The mammalian TRPC cation channels [PDF]

open access: yesBiochimica Et Biophysica Acta - Molecular Cell Research, 2004
Transient Receptor Potential-Canonical (TRPC) channels are mammalian homologs of Transient Receptor Potential (TRP), a Ca2+-permeable channel involved in the phospholipase C-regulated photoreceptor activation mechanism in Drosophila.
Mohamed Trebak   +2 more
exaly   +4 more sources

TRPC channels as STIM1-regulated store-operated channels [PDF]

open access: yesCell Calcium, 2007
Receptor-activated Ca2+ influx is mediated largely by store-operated channels (SOCs). TRPC channels mediate a significant portion of the receptor-activated Ca2+ influx.
Min Goo Lee, Guo N Huang, Paul Worley
exaly   +5 more sources

Mechanisms of lipid regulation and lipid gating in TRPC channels [PDF]

open access: yesCell Calcium, 2016
TRPC proteins form cation channels that integrate and relay cellular signals by mechanisms involving lipid recognition and lipid-dependent gating. The lipohilic/amphiphilic molecules that function as cellular activators or modulators of TRPC proteins ...
Klaus Gröschner, Barbora Svobodova
exaly   +2 more sources

Subunit composition, molecular environment, and activation of native TRPC channels encoded by their interactomes [PDF]

open access: yesNeuron, 2022
peer reviewedIn the mammalian brain TRPC channels, a family of Ca2+-permeable cation channels, are involved in a variety of processes from neuronal growth and synapse formation to transmitter release, synaptic transmission and plasticity.
Bernd Fakler   +2 more
exaly   +2 more sources

Determining the functional role of TRPC channels in primary cells

open access: yesPflugers Archiv European Journal of Physiology, 2005
Although the TRPC members of the mammalian transient receptor potential TRP cation channel family were the first to be described in 1995, the depth of knowledge of TRPC channels has fallen behind that of their counterparts in the TRPV and TRPM ...
Martin Gosling
exaly   +2 more sources
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Trafficking mechanisms and regulation of TRPC channels

Cell Calcium, 2014
TRPC channels are Ca(2+)-permeable cation channels which are regulated downstream from receptor-coupled PIP2 hydrolysis. These channels contribute to a wide variety of cellular functions. Loss or gain of channel function has been associated with dysfunction and aberrant physiology.
Lorena Brito de Souza, Indu Ambudkar
exaly   +3 more sources

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