Results 111 to 120 of about 6,724 (162)

Integrative genomic, phylogenetic, and transcriptomic analyses reveal temperature-responsive transient receptor potential (TRP) genes in Pacific abalone Haliotis discus hannai. [PDF]

BMC Ecol Evol
Kim MA, Sohn YC.
europepmc   +1 more source

Differential Sensitivity of TRPC- and ORAI-Mediated Calcium Entries to 1‑[2-(4-Methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl]imidazole Chloride (SKF-96365). [PDF]

ACS Pharmacol Transl Sci
Susperreguy S, Formoso K, Mansilla Ricartti J, Freichel M, Birnbaumer L.   +4 more
europepmc   +1 more source

TRPC3 and TRPC6: Multimodal Cation-Conducting Channels Regulating Cardiovascular Contractility and Remodeling. [PDF]

Cells
Numaga-Tomita T, Nishida M.
europepmc   +1 more source

The Potential Role of Calcium Channels in Pulmonary Hypertension. [PDF]

Biomed Res Int
Wu P, Zhong D, He X, Li Y, Zhang H.
europepmc   +1 more source

The mammalian TRPC cation channels

Biochimica Et Biophysica Acta - Molecular Cell Research, 2004
Transient Receptor Potential-Canonical (TRPC) channels are mammalian homologs of Transient Receptor Potential (TRP), a Ca(2+)-permeable channel involved in the phospholipase C-regulated photoreceptor activation mechanism in Drosophila. The seven mammalian TRPCs constitute a family of channels which have been proposed to function as store-operated as ...
Mohamed Trebak, James Putney, Guillermo Vazquez   +2 more
exaly   +3 more sources

TRPC channels as STIM1-regulated store-operated channels [PDF]

Cell Calcium, 2007
Receptor-activated Ca(2+) influx is mediated largely by store-operated channels (SOCs). TRPC channels mediate a significant portion of the receptor-activated Ca(2+) influx. However, whether any of the TRPC channels function as a SOC remains controversial.
Min Goo Lee, Guo N Huang, Paul Worley
exaly   +4 more sources

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Trafficking mechanisms and regulation of TRPC channels

Cell Calcium, 2014
TRPC channels are Ca(2+)-permeable cation channels which are regulated downstream from receptor-coupled PIP2 hydrolysis. These channels contribute to a wide variety of cellular functions. Loss or gain of channel function has been associated with dysfunction and aberrant physiology.
Lorena Brito De Souza, Indu Ambudkar
exaly   +3 more sources

TRPC channels as signal transducers

Pflügers Archiv - European Journal of Physiology, 2005
The study of the TRPC cation channels as signal transducers in sensory neurons is in its infancy. Mechanoreceptors that monitor arterial pressure are prime candidates for the involvement of TRPC channels as either primary mechanical transducers or as modulators of the transduction process. Their activity patterns can be regulated by growth factors such
Patricia A, Glazebrook, William P, Schilling, Diana L, Kunze   +2 more
openaire   +2 more sources

TRPCs as MS Channels

2007
This chapter reviews recent evidence indicating that canonical or classical transient receptor potential (TRPC) channels are directly or indirectly mechanosensitive (MS) and can therefore be designated as mechano-operated channels (MOCs). The MS functions of TRPCs may be mechanistically related to their better known functions as store-operated and ...
Owen P, Hamill, Rosario, Maroto
openaire   +2 more sources

TRPC channels in vascular cell function

Thrombosis and Haemostasis, 2010
SummaryThe mammalian transient receptor potential (TRP) superfamily of non-selective cation channels can be divided into six major families. Among them, the “classical” or “canonical” TRPC family is most closely related to Drosophila TRP, the founding member of the superfamily.
Thomas Gudermann, Alexander Dietrich, Hermann Kalwa   +2 more
exaly   +3 more sources