Results 91 to 100 of about 802,879 (181)

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, Volume 102, Issue 4, Page 797-831, July/August 2026.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

Structure of the human lipid-gated cation channel TRPC3

eLife, 2018
The TRPC channels are crucially involved in store-operated calcium entry and calcium homeostasis, and they are implicated in human diseases such as neurodegenerative disease, cardiac hypertrophy, and spinocerebellar ataxia.
Chen Fan, Wooyoung Choi, Weinan Sun, Juan Du, Wei Lü   +4 more
doaj   +1 more source

5‐Hydroxytryptamine Distribution Alteration in Both Neuron and Synapse of Tg(SOD1*G93A)1gur Mice: A Potential Intervention Candidate Strategy for Amyotrophic Lateral Sclerosis

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
This study reveals that 5‐hydroxytryptamine (5‐HT) synapses in the spinal cord and 5‐HT neurons in the brainstem of the SOD1‐G93A amyotrophic lateral sclerosis (ALS) mouse model are significantly altered, showing a decrease in pre‐symptomatic stages but a marked increase as the disease progresses.
Lijun Zhou, Menghua Li, Qi Dai, Xiwang Liu, Cheng Li, Huifeng Jiao, Haili Pan, Renshi Xu   +7 more
wiley   +1 more source

Does erythropoietin regulate TRPC channels in red blood cells? [PDF]

, 2017
BACKGROUND Cation channels play an essential role in red blood cells (RBCs) ion homeostasis. One set of ion channels are the transient receptor potential channels of canonical type (TRPC channels).
Hertz, Laura, Krause, Elmar, Anna Bogdanova, Lutz Birnbaumer, Lars Kaestner, Jens Danielczok, Lipp, Peter, Ruppenthal, Sandra, Laura Hertz, Birnbaumer, Lutz, Polina Petkova-Kirova, Petkova-Kirova, Polina, Bogdanova, Anna, Kaestner, Lars, Sandra Ruppenthal, Peter Lipp, Kaiser, Elisabeth, Elisabeth Kaiser, Marc Freichel, Petkova Kirova, Polina, Elmar Krause, Danielczok, Jens, Freichel, Marc   +22 more
core   +1 more source

Abnormal expression, localization and interaction of canonical transient receptor potential ion channels in human breast cancer cell lines and tissues: a potential target for breast cancer diagnosis and therapy

Cancer Cell International, 2009
Background Ca2+ is known to be involved in a number of metastatic processes including motility and proliferation which can result in store-depletion of Ca2+.
Djamgoz Mustafa, Yeo Syn, Aydar Ebru, Palmer Christopher   +3 more
doaj   +1 more source

CaR-mediated vasodilatation: Role of endothelium TRPC channels

, 2012
There is increasing evidence that Ca2+-sensing G-protein-coupled receptors (CaR) have an important role in modulating vascular activity; both CaR-mediated contraction and dilation responses have been proposed.
Greenwood, Iain A., Ho, W. S. Vanessa, Chadha, Preet S., Mclough, Jessica, Greenberg, Harry Z. E., Albert, Anthony, Shi, Julia   +6 more
core   +1 more source

Single-cell RT-PCR Analysis and CRF Effects on TRPC Channels Expressed in Rat Brain [PDF]

, 2012
The canonical transient receptor potential (TRPC) channels comprise a family of nonselective cation channels composed of seven members (TRPC1-7). TRPC channels are widely distributed in the nervous system and contribute to neuronal excitation.
Nicole M. Jones (6498536)
core   +4 more sources

Classical Transient Receptor Potential 1 (TRPC1): Channel or Channel Regulator?

Cells, 2014
In contrast to other Classical Transient Receptor Potential TRPC channels the function of TRPC1 as an ion channel is a matter of debate, because it is often difficult to obtain substantial functional signals over background in response to over-expression
Alexander Dietrich, Meike Fahlbusch, Thomas Gudermann   +2 more
doaj   +1 more source

Expression of Transient Receptor Potential Canonical Channel Proteins in Human Non-small Cell Lung Cancer

Chinese Journal of Lung Cancer, 2010
Background and objective Transient receptor potential canonical (TRPC) proteins, a group of Ca2+ permeable nonselective cation channels, are thought to constitute store-operated calcium channels (SOCC) and mediate store-operated calcium entry (SOCE) in ...
Qi ZHANG, Jianxing HE, Wenju LU, Weiqiang YIN, Haihong YANG, Xiaoming XU, Daoyuan WANG   +6 more
doaj  

TRPC1 Channels Are Expressed in Pyramidal Neurons and in a Subset of Somatostatin Interneurons in the Rat Neocortex

Frontiers in Neuroanatomy, 2018
Disturbances in calcium homeostasis due to canonical transient receptor potential (TRPC) and/or store-operated calcium (SOC) channels can play a key role in a large number of brain disorders.
Juan R. Martinez-Galan, Ana Verdejo, Elena Caminos   +2 more
doaj   +1 more source