Results 81 to 90 of about 6,649 (159)

Expression of Transient Receptor Potential Canonical Channel Proteins in Human Non-small Cell Lung Cancer

Chinese Journal of Lung Cancer, 2010
Background and objective Transient receptor potential canonical (TRPC) proteins, a group of Ca2+ permeable nonselective cation channels, are thought to constitute store-operated calcium channels (SOCC) and mediate store-operated calcium entry (SOCE) in ...
Qi ZHANG, Jianxing HE, Wenju LU, Weiqiang YIN, Haihong YANG, Xiaoming XU, Daoyuan WANG   +6 more
doaj  

TRPC1 Channels Are Expressed in Pyramidal Neurons and in a Subset of Somatostatin Interneurons in the Rat Neocortex

Frontiers in Neuroanatomy, 2018
Disturbances in calcium homeostasis due to canonical transient receptor potential (TRPC) and/or store-operated calcium (SOC) channels can play a key role in a large number of brain disorders.
Juan R. Martinez-Galan, Ana Verdejo, Elena Caminos   +2 more
doaj   +1 more source

Pharmacological Properties of Novel TRPC Channel Inhibitors

YAKUGAKU ZASSHI, 2010
Ca(2+) signals control diverse cellular processes, ranging from ubiquitous activities like gene expression to tissue specific responses such as lymphocyte activation and cardiac diseases. TRPC channels control Ca(2+) influxes that induce diverse cellular processes upon stimulation of plasma membrane receptors coupled to phospholipase C (PLC). Invention
Kiyonaka, Shigeki, Kato, Kenta, Nishida, Motohiro, Mori, Yasuo   +3 more
openaire   +3 more sources

Immunohistochemistry Reveals TRPC Channels in the Human Hearing Organ-A Novel CT-Guided Approach to the Cochlea. [PDF]

Int J Mol Sci, 2023
Englisch CN, Steinhäuser J, Wemmert S, Jung M, Gawlitza J, Wenzel G, Schick B, Tschernig T.   +7 more
europepmc   +1 more source

TRPC channels as emerging targets for seizure disorders. [PDF]

Trends Pharmacol Sci, 2022
Yu Y, Li W, Jiang J.
europepmc   +1 more source

TRPC Channels in the Physiology and Pathophysiology of the Renal Tubular System: What Do We Know? [PDF]

Int J Mol Sci, 2022
Englisch CN, Paulsen F, Tschernig T.
europepmc   +1 more source

Dysregulation of Podocyte BK Channels and Nephrosis: Effects of Circulating Factors and Auxiliary β4 Subunits

Cells
Podocytes express large-conductance Ca2+-activated K+ channels (BK channels) and at least two different pore-forming KCa1.1 subunit C-terminal splice variants, known as VEDEC and EMVYR, along with auxiliary β and γ subunits.
Eun Young Kim, Patrycja Rachubik, Stuart E. Dryer   +2 more
doaj   +1 more source

TRPC channels blockade abolishes endotoxemic cardiac dysfunction by hampering intracellular inflammation and Ca²⁺ leakage. [PDF]

Nat Commun, 2022
Tang N, Tian W, Ma GY, Xiao X, Zhou L, Li ZZ, Liu XX, Li CY, Wu KH, Liu W, Wang XY, Gao YY, Yang X, Qi J, Li D, Liu Y, Chen WS, Gao J, Li XQ, Cao W.   +19 more
europepmc   +1 more source

Characterization of DAG Binding to TRPC Channels by Target-Dependent <i>cis-trans</i> Isomerization of OptoDArG. [PDF]

Biomolecules, 2022
Erkan-Candag H, Krivic D, Gsell MAF, Aleksanyan M, Stockner T, Dimova R, Tiapko O, Groschner K.   +7 more
europepmc   +1 more source

Mechanisms and significance of Ca²⁺ entry through TRPC channels. [PDF]

Curr Opin Physiol, 2020
Bacsa B, Tiapko O, Stockner T, Groschner K.   +3 more
europepmc   +1 more source