Results 101 to 110 of about 802,879 (181)

TRPC Channels in human mast cells [PDF]

, 2011
Mast cells have an important role in the immune system, but they are centrally involved in the pathophysiology of asthma, along with a number of other allergic diseases including rhinitis, eczema and irritable bowel disease (Metcalfe et al., 1997; Beaven,
Tree-Booker, Claire
core  

Mechanism and functional significance of TRPC channel multimerization [PDF]

Seminars in Cell & Developmental Biology, 2006
Ca(2+) signaling regulates many important physiological events within a diverse set of living organisms. In particular, sustained Ca(2+) signals play an important role in controlling cell proliferation, cell differentiation and the activation of immune cells.
openaire   +2 more sources

A key role of TRPC channels in the regulation of electromechanical activity of the developing heart

, 2011
Aims It is well established that dysfunction of voltage-dependent ion channels results in arrhythmias and conduction disturbances in the foetal and adult heart.
Elodie Robin, Jessica Sabourin, Eric Raddatz, Raddatz, E., Robin, E., Sabourin, J.   +5 more
core   +1 more source

A key role of TRPC channels in the regulation of electromechanical activity of the developing heart [PDF]

, 2017
Aims It is well established that dysfunction of voltage-dependent ion channels results in arrhythmias and conduction disturbances in the foetal and adult heart.
Raddatz, Eric, Robin, Elodie, Sabourin, Jessica   +2 more
core  

TRPC Channels in the Physiology and Pathophysiology of the Renal Tubular System: What Do We Know? [PDF]

Int J Mol Sci, 2022
Englisch CN, Paulsen F, Tschernig T.
europepmc   +1 more source

Dysregulation of Podocyte BK Channels and Nephrosis: Effects of Circulating Factors and Auxiliary β4 Subunits

Cells
Podocytes express large-conductance Ca2+-activated K+ channels (BK channels) and at least two different pore-forming KCa1.1 subunit C-terminal splice variants, known as VEDEC and EMVYR, along with auxiliary β and γ subunits.
Eun Young Kim, Patrycja Rachubik, Stuart E. Dryer   +2 more
doaj   +1 more source

TRPC channels blockade abolishes endotoxemic cardiac dysfunction by hampering intracellular inflammation and Ca²⁺ leakage. [PDF]

Nat Commun, 2022
Tang N, Tian W, Ma GY, Xiao X, Zhou L, Li ZZ, Liu XX, Li CY, Wu KH, Liu W, Wang XY, Gao YY, Yang X, Qi J, Li D, Liu Y, Chen WS, Gao J, Li XQ, Cao W.   +19 more
europepmc   +1 more source

Investigation of TRPC channels in health and disease in cerebellum

, 2008
In the brain, classical (canonical) transient receptor potential (TRPC) channels are thought to be involved in different aspects of neuronal development.
Huang, Wan Chen
core  

Murine cardiac growth, TRPC channels, and cGMP kinase I

, 2015
Domes K, Patrucco E, Loga F, et al. Murine cardiac growth, TRPC channels, and cGMP kinase I. Pflügers Archiv - European Journal of Physiology. 2015;467(10):2229-2234.Signaling via cGMP-dependent protein kinase I (cGKI) and canonical transient receptor ...
Domes, Katrin, Loga, Florian, Hofmann, Franz, Birnbaumer, Lutz, Wegener, Jörg ; https://orcid.org/, Patrucco, Enrico, Dietrich, Alexander   +6 more
core   +1 more source

Characterization of DAG Binding to TRPC Channels by Target-Dependent <i>cis-trans</i> Isomerization of OptoDArG. [PDF]

Biomolecules, 2022
Erkan-Candag H, Krivic D, Gsell MAF, Aleksanyan M, Stockner T, Dimova R, Tiapko O, Groschner K.   +7 more
europepmc   +1 more source