Results 141 to 150 of about 6,649 (159)
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TRPC Channels in Cardiac Hypertrophy
2013Impaired cardiomyocyte Ca2+ handling is considered as crucial factor programming cardiac hypertrophy and heart failure. It has, however, not been entirely resolved what type of Ca2+ signals is involved in mechanisms inducing hypertrophic remodelling.
Nadine Kirschmer +2 more
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TRPC Channels: Integrators of Multiple Cellular Signals
2007TRPC channels are ubiquitously expressed among cell types and mediate signals in response to phospholipase C (PLC)-coupled receptors. TRPC channels function as integrators of multiple signals resulting from receptor-induced PLC activation, which catalyzes the breakdown of phosphatidylinositol 4,5-bisphosphate (PIP2) to produce inositol 1,4,5 ...
J, Soboloff +9 more
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Mammalian TRPC channel subunit assembly.
Novartis Foundation symposium, 2004TRPC genes encode a family of ion channel proteins that appear to be responsible for Ca2+ influx following stimulation of membrane receptors linked to phospholipase C. TRPC channels are thought to be tetrameric, and there is growing evidence to suggest heteromultimeric channel assembly.
William P, Schilling, Monu, Goel
openaire +1 more source
Pharmacology of TRPC Channels and Its Potential in Cardiovascular and Metabolic Medicine
Annual Review of Pharmacology and Toxicology, 2022David J Wright +2 more
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Calcium transport and sensing in TRPC channels – New insights into a complex feedback regulation
Cell Calcium, 2023Oleksandra Tiapko, Klaus Groschner
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Homer Binds TRPC Family Channels and Is Required for Gating of TRPC1 by IP3 Receptors
Cell, 2003Kirill Kiselyov +2 more
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TRPC Channels: Dysregulation and Ca2+ Mishandling in Ischemic Heart Disease
Cells, 2020Débora Falcón +2 more
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