Results 91 to 100 of about 2,388 (162)

Targeting TRPM3 as a potential therapeutic approach for autosomal dominant polycystic kidney disease

Scientific Reports
Cystic diseases, especially autosomal dominant polycystic kidney disease (ADPKD; incidence approx. 1/1000), are a leading cause of renal failure, caused by appearance and growth of renal cysts that can lead to renal failure in middle age.
Hüseyin Gül, Jamie A. Davies
doaj   +1 more source

Lipid raft disruption inhibits the activation of Transient Receptor Potential Vanilloid 1, but not TRP Melastatin 3 and the voltage-gated L-type calcium channels in sensory neurons

Frontiers in Cell and Developmental Biology
Transient Receptor Potential (TRP) ion channels like Vanilloid 1 (TRPV1) and Melastatin 3 (TRPM3) are nonselective cation channels expressed in primary sensory neurons and peripheral nerve endings, which are located in cholesterol- and sphingolipid-rich ...
Maja Payrits, Maja Payrits, Maja Payrits, Balázs Zoltán Zsidó, Balázs Zoltán Zsidó, Andrea Kinga Nehr-Majoros, Andrea Kinga Nehr-Majoros, Andrea Kinga Nehr-Majoros, Rita Börzsei, Rita Börzsei, Zsuzsanna Helyes, Zsuzsanna Helyes, Zsuzsanna Helyes, Csaba Hetényi, Csaba Hetényi, Éva Szőke, Éva Szőke, Éva Szőke   +17 more
doaj   +1 more source

TRPM3 Gene [PDF]

, 2020
openaire   +1 more source

TRPM3 wt Allele [PDF]

, 2020
openaire   +1 more source

Non-canonical pore architecture underlies constitutive gating of human retinal TRPM1. [PDF]

Nat Commun
Sharma M, Nageswar KV, Kumar V, Chattopadhyay A, Varshney N, Chettri R, Nanda S, Martemyanov KA, Singh AK.   +8 more
europepmc   +1 more source

Phosphoinositide regulation of TRPM channels – TRPM3 joins the club! [PDF]

Channels, 2016
Tóth, Balázs István, Oberwinkler, Johannes, Voets, Thomas   +2 more
openaire   +4 more sources

Special Issue "Molecular Links Between Sensory Nerves, Inflammation, and Pain 3.0". [PDF]

Int J Mol Sci
Szőke É, Helyes Z.
europepmc   +1 more source

Phenotype Spectrum of TRPM3-Associated Disorders

Objective: Monoallelic variants in the transient receptor potential melastatin-related type 3 gene (TRPM3) have been associated with neurodevelopmental manifestations, but knowledge on the clinical manifestations and treatment options is limited. We characterized the clinical spectrum, highlighting particularly the epilepsy phenotype, and the effect of
Jolitz,Laura, Helbig,Ingo, Fitzgerald,Mark P., McKeown Ruggiero,Sarah, Cohen,Stacey, Angelini,Chloe, Vallespin,Elena, Michaud,Vincent, Gerasimenko,Anna, Cogne,Benjamin, Isidor,Bertrand, Keren,Boris, Dyment,David, Heron,Delphine, Karstensen,Helena Gásdal, Cuppen, Inge, Christodoulou,John, Wilson,Meredith, Lake,Nicole J., Biskup,Saskia, Syrbe,Steffen, Mori,Takayasu, Becker,Lena Luise, Kaindl,Angela M., Neurologen   +24 more
openaire   +1 more source

Editorial: Unraveling the biological mechanisms of chronic fatigue: a multifaceted approach. [PDF]

Front Med (Lausanne)
Almulla AF, Natelson BH, Calabrese LH, Jahanbani F.   +3 more
europepmc   +1 more source

TRPM3 mediates spontaneous pain and mechanical allodynia in a mouse model of chronic orofacial neuropathy. [PDF]

Cell Rep Med
Deseure K, Dallali I, Pinto S, Luyten K, Segal A, Van Ranst N, Roelens R, Corbett S, Murray S, Persoons E, Hans G, Vriens J, Voets T.   +12 more
europepmc   +1 more source