Tissue Distribution Profiles of the Human TRPM Cation Channel Family
Journal of Receptor and Signal Transduction Research, 2006Eight members of the TRP-melastatin (TRPM) subfamily have been identified, whose physiological functions and distribution are poorly characterized. Although tissue expression and distribution patterns have been reported for individual TRPM channels, comparisons between individual studies are not possible because of variations in analysis techniques and
Paul R Murdock
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On the Connections between TRPM Channels and SOCE [PDF]
Cells, 2022 Plasma membrane protein channels provide a passageway for ions to access the intracellular milieu. Rapid entry of calcium ions into cells is controlled mostly by ion channels, while Ca2+-ATPases and Ca2+ exchangers ensure that cytosolic Ca2+ levels ...
Guilherme Henrique Souza Bomfim +2 more
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TRPM Family Channels in Cancer
Pharmaceuticals, 2018 Members of the TRPM (“Melastatin”) family fall into the subclass of the TRP channels having varying permeability to Ca2+ and Mg2+, with three members of the TRPM family being chanzymes, which contain C-terminal enzyme domains.
V'Yacheslav Lehen'Kyi +2 more
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Interaction of Calmodulin with TRPM: An Initiator of Channel Modulation
International Journal of Molecular Sciences, 2023 Transient receptor potential melastatin (TRPM) channels, a subfamily of the TRP superfamily, constitute a diverse group of ion channels involved in mediating crucial cellular processes like calcium homeostasis.
Katerina Jirásková +2 more
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The oncogenic roles of TRPM ion channels in cancer [PDF]
Journal of Cellular Physiology, 2019 Transient receptor potential (TRP) proteins are a diverse family of ion channels present in multiple types of tissues. They function as gatekeepers for responses to sensory stimuli including temperature, vision, taste, and pain through their activities ...
Kah Keng Wong +2 more
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Oxidative stress-modulated TRPM ion channels in cell dysfunction and pathological conditions in humans [PDF]
Cellular Signalling, 2013 Artículo de publicación ISIThe transient receptor potential melastatin (TRPM) protein family is an extensive group of ion channels expressed in several types of mammalian cells.
Claudio Cabello-Verrugio +2 more
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Roles of TRPM channels in glioma
Cancer Biology and TherapyGliomas are the most common type of primary brain tumor. Despite advances in treatment, it remains one of the most aggressive and deadly tumor of the central nervous system (CNS). Gliomas are characterized by high malignancy, heterogeneity, invasiveness,
Erbao Bian, Dasheng Tian
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The TRPM Cation Channels in the Immune Context
Current Pharmaceutical Design, 2005The molecular identification of novel ion channels expressed in the immune context provides very attractive potential targets for new therapeutic drugs designed to modulate immune system function. Several members of the recently discovered TRPM family of cation channels are expressed in immune cells.
C, Schmitz, A-L, Perraud
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Fare in vitro alzheimer modelinde hipokampus trpa1, TRPM2 ve TRPV1 katyon kanalları üzerinde homosistein ile memantin'in etkilerinin araştırılması = Effects of homocysteine and memantine on TRPA1, TRPM and TRPV1 cation channels in mouse hippocampus of in vitro alzheimer's disease model / [PDF]
Tez (Doktora) - Süleyman Demirel Üniversitesi, Sağlık Bilimleri Enstitüsü, Sinir Bilimleri Anabilim Dalı, 2017.
Övey, İshak Suat, 1984- 62324 author +2 more
openaire
On the modulation of TRPM channels: Current perspectives and anticancer therapeutic implications
Frontiers in Oncology, 2023Isabel María Gómez Monterrey +2 more
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