Results 81 to 90 of about 5,720 (153)

Genomic and non-genomic effects of androgens in the cardiovascular system: clinical implications [PDF]

, 2017
The principle steroidal androgens are testosterone and its metabolite 5α-dihydrotestosterone (DHT), which is converted from testosterone by the enzyme 5α-reductase.
Ahmed, S. Faisal, Alves-Lopes, Rheure, Lucas-Herald, Angela K., Montezano, Augusto C., Touyz, Rhian M.   +4 more
core   +1 more source

Ruling out pyridine dinucleotides as true TRPM2 channel activators reveals novel direct agonist ADP-ribose-2'-phosphate [PDF]

, 2015
Transient receptor potential melastatin 2 (TRPM2), a Ca(2+)-permeable cation channel implicated in postischemic neuronal cell death, leukocyte activation, and insulin secretion, is activated by intracellular ADP ribose (ADPR).
Aarhus, Balázs Tóth, Beck, Brailoiu, Calcraft, Churamani, Csanády, Fliegert, Fonfria, Hara, Hermosura, Iordan Iordanov, Kaneko, Koch-Nolte, Kolisek, Lange, Lin, László Csanády, Malavasi, McHugh, Moreau, Nagamine, Olah, Perraud, Perraud, Perraud, Perraud, Sano, Schmid, Togashi, Tóth, Tóth, Tóth, Uchida, Wang, Wehage, Yamamoto   +36 more
core   +2 more sources

ASIC3 Channels Integrate Agmatine and Multiple Inflammatory Signals through the Nonproton Ligand Sensing Domain [PDF]

, 2010
Background: Acid-sensing ion channels (ASICs) have long been known to sense extracellular protons and contribute to sensory perception. Peripheral ASIC3 channels represent natural sensors of acidic and inflammatory pain. We recently reported the use of a
Wei-Guang Li, Ye Yu, Zhu-Dan Zhang, Hui Cao, Tian-Le Xu   +4 more
core   +2 more sources

Fare in vitro alzheimer modelinde hipokampus trpa1, TRPM2 ve TRPV1 katyon kanalları üzerinde homosistein ile memantin'in etkilerinin araştırılması = Effects of homocysteine and memantine on TRPA1, TRPM and TRPV1 cation channels in mouse hippocampus of in vitro alzheimer's disease model / [PDF]

Tez (Doktora) - Süleyman Demirel Üniversitesi, Sağlık Bilimleri Enstitüsü, Sinir Bilimleri Anabilim Dalı, 2017.
Övey, İshak Suat, 1984- 62324 author, Nazıroğlu, Mustafa, 1968- thesis advisor 10271, Süleyman Demirel Üniversitesi. Sağlık Bilimleri Enstitüsü. Sinir Bilimleri Anabilim Dalı. 167235 issuing body   +2 more
openaire  

Acute neuroinflammation induces AIS structural plasticity in a NOX2-dependent manner [PDF]

, 2017
Background Chronic microglia-mediated inflammation and oxidative stress are well-characterized underlying factors in neurodegenerative disease, whereby reactive inflammatory microglia enhance ROS production and impact neuronal integrity. Recently, it has
Benusa, S. D., DeVries, G. H., Dupree, J. L., George, N. M., Sword, B. A.   +4 more
core   +1 more source

Another TRP to endothelial dysfunction [PDF]

, 2008
Dietrich, Alexander, Gudermann, Thomas
core   +1 more source

Requirement for the N-Terminal Coiled-Coil Domain for Expression and Function, but not Subunit Interaction of, the ADPR-Activated TRPM2 Channel [PDF]

, 2009
Zhu-Zhong Mei, Lin-Hua Jiang, DE Clapham, I Erler, A Fleig, E Fonfria, Y Hara, CM Hecquet, K Hill, L-H Jiang, R Kraft, P Launay, PK Lepage, A Lupas, ZZ Mei, ZZ Mei, M Naziroğlu, M Naziroğlu, B Nilius, AL Perraud, IS Ramsey, Y Sano, R Schindl, K Togashi, PR Tsuruda, K Venkatachalam, E Wehage, R Xia, S Yamamoto, W Zhang, W Zhang   +30 more
core   +1 more source

Integrative genomic, phylogenetic, and transcriptomic analyses reveal temperature-responsive transient receptor potential (TRP) genes in Pacific abalone Haliotis discus hannai. [PDF]

BMC Ecol Evol
Kim MA, Sohn YC.
europepmc   +1 more source

TRP channels in epileptogenesis: calcium dysregulation mechanisms and pharmacological targeting strategies. [PDF]

Front Mol Neurosci
Deng G, Liu D, Zhong Y, Wang M, Su B, Jiang H, Zhai Y, Peng H, Zhang C, Feng J.   +9 more
europepmc   +1 more source

TRP Channels from Sensory Coding to Physiology. [PDF]

Metabolites
Atif M, Lee Y.
europepmc   +1 more source