Results 131 to 140 of about 3,697 (189)

Autophagy-lysosomal pathway in neurodegeneration. [PDF]

Mol Neurodegener Adv
McDonough SR, Rao AK, McAleer JM, Babrowicz BM, Sharma M.   +4 more
europepmc   +1 more source

TRPM2 Promotes Lipophagy Through TFEB and LAL in HFD-Fed Mice. [PDF]

Cells
Ying F, Zhuo D, Zhou S, Jiang L, Yao X.
europepmc   +1 more source

Beyond Neurodegeneration: White Matter Vacuolation as a Primary Myelin Defect. [PDF]

Int J Mol Sci
Misra S, Gunn TM.
europepmc   +1 more source

Visualization of lysosomal membrane proteins by cryo electron tomography. [PDF]

Nat Commun
McVeigh BM, De Jesús-Pérez JJ, Siepe DH, Gogoi P, Mageswaran SK, Kalocsay M, Mihelc EM, Moiseenkova-Bell VY.   +7 more
europepmc   +1 more source

A novel Bi-Allelic pathogenic MCOLN1 variant underlying mucolipidosis type IV in an Iranian family: clinical, genetic, and molecular dynamics-based structural analysis. [PDF]

BMC Med Genomics
Mohsenipour M, Nejati P, Khosravi T, Alimoradi E, Salehi M, Oladnabi M, Alibakhshi R.   +6 more
europepmc   +1 more source

The lysosomal carrier SLC29A3 supports antibacterial signaling, and promotes autophagy by activating TRPML1 in murine dendritic cells. [PDF]

Proc Natl Acad Sci U S A
Netting DJ, López-Haber C, Hutchins Z, Martina JA, Puertollano R, Mantegazza AR.   +5 more
europepmc   +1 more source

Obinutuzumab induces lysosomal destabilization via sphingomyelin-dependent inhibition of TRPML2. [PDF]

Sci Rep
Oh J, Jin N, Kwon S, Lee C, Baek H, Lee D, Kim JY.   +6 more
europepmc   +1 more source

Astrocytes mobilize a broader repertoire of lysosomal repair mechanisms than neurons. [PDF]

iScience
Smith EM, Chanaday NL, Maday S.
europepmc   +1 more source

Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC. [PDF]

Front Immunol
Ouologuem L, Kübler A, Ouologuem S, Hadzic A, Stöckl JB, Siciliano AC, Forciniti S, Nigro S, Iuele H, Onesto V, Nguyen A, Matzek D, Abrahamian C, Grimm C, Popper B, Gigli G, Del Mercato LL, Merkel OM, Fröhlich T, Theurich S, Bartel K.   +20 more
europepmc   +1 more source

Acid ceramidase as a novel target for adiponectin receptor agonist to abrogate podocyte NLRP3 inflammasome activation and glomerular inflammation during obesity. [PDF]

J Pharmacol Exp Ther
Li G, Huang D, Kidd JM, Zou Y, Wu X, Zhang Y, Gehr TWB, Li N, Li PL.   +8 more
europepmc   +1 more source