Results 141 to 150 of about 3,697 (189)

Physiological functions and pharmacological targeting of transient receptor potential channels. [PDF]

Pharmacol Rev
Chubanov V, Grimm C, Hill K, Schaefer M, Köttgen M, Storch U, Mederos Y Schnitzler M, Kudrina V, Erbacher A, Gudermann T.   +9 more
europepmc   +1 more source

TRPML2 in distinct states reveals the activation and modulation principles of the TRPML family. [PDF]

Nat Commun
Schmiege P, Jaślan D, Fine M, Sadanandan NP, Hatton A, Elghobashi-Meinhardt N, Grimm C, Li X.   +7 more
europepmc   +1 more source

TRPML3‑mediated lysosomal Ca²⁺ release enhances drug sequestration and biogenesis, promoting osimertinib resistance in non‑small cell lung cancer. [PDF]

Oncol Rep
Kim MS, Kim MS.
europepmc   +1 more source

eLife Assessment: TRPML1 gating modulation by allosteric mutations and lipids (Design of allosteric mutations that recapitulate the gating of TRPML1)

openaire   +1 more source

Lysosomal ion channels and pain. [PDF]

Pain Rep
Liu W, Li Y, Bao Y, Tan ZY.
europepmc   +1 more source

Lysosome heterogeneity and diversity mapped through its distinct cellular functions. [PDF]

Cell Mol Life Sci
Chavan I, Bhattacharjee A.
europepmc   +1 more source

DMXL1 promotes recruitment of V1-ATPase to lysosomes upon TRPML1 activation. [PDF]

Nat Struct Mol Biol
Lee C, Eldridge MJG, Gonzalez-Lozano MA, Bresnahan T, Niday Z, Del Camino D, Fu T, Paulo JA, Moran MM, Helaine S, Harper JW.   +10 more
europepmc   +1 more source

From plasma membrane to lysosomes: expanding roles of TMEM63/OSCA channels in mechanosensation and intracellular signaling. [PDF]

Front Pharmacol
Erdogmus S, Mollaoglu G, Storch U.
europepmc   +1 more source

Microenvironmental Drivers of Bone Disease in Multiple Myeloma: Oxidative Stress, Sterile Inflammation, Autophagy-Lysosomal Remodeling, and the Iron-Lipid Peroxidation Axis. [PDF]

Biomolecules
Nasso ME, Bottaro A, Fazio M, Stagno F, Gangemi S, Allegra A.   +5 more
europepmc   +1 more source

Reviewer #2 (Public Review): TRPML1 gating modulation by allosteric mutations and lipids (Design of allosteric mutations that recapitulate the gating of TRPML1)

openaire   +1 more source