Results 111 to 120 of about 3,697 (189)

Lysosomal Ion Channel TRPML1 Contributes to Neuropathic Pain Associated With Diabetic Peripheral Neuropathy in Mice. [PDF]

Diabetes
Yang Y, Teng S, Zhang Y, Ji YH, Wang H, Tan ZY.   +5 more
europepmc   +1 more source

IP3R2-mediated inter-organelle calcium signaling suppresses melanosome degradation. [PDF]

PLoS Biol
Saurav S, Jadon A, Motiani RK.
europepmc   +1 more source

Mucolipin 1 (TRPML1; MCOLN1) [PDF]

Science-Business eXchange, 2008
openaire   +1 more source

Podocyte-specific acid sphingomyelinase overexpression promotes gasdermin D dependent pyroptosis by impairing autophagic flux during obesity. [PDF]

Front Physiol
Huang D, Zou Y, Chan E, Kidd JM, Wu X, Zhang Y, Gehr TWB, Li N, Li PL, Li G.   +9 more
europepmc   +1 more source

Role of TRP channels in lymphatic function. [PDF]

Front Physiol
Cao X, Chen YL.
europepmc   +1 more source

Therapeutic targeting of lysosome-triggered inflammatory channels in nasal and upper-airway allergic conditions. [PDF]

Front Immunol
Yu H, Zheng Y, Wu D, Zhou L, Jiang K, Tian K, Shen N.   +6 more
europepmc   +1 more source

A conserved VPS34-PIKfyve-TRPML1-myosin II axis regulates the speed of amoeboid cell migration. [PDF]

EMBO Rep
Dehio P, Michard C, Yam-Puc JC, Martí I Líndez AA, Jandke A, Unterstab G, Fabre L, Sauteur L, Artinger M, Legler DF, Sixt M, Schaefer T, Wymann MP, Okkenhaug K, Soldati T, Mehling M, Hess C.   +16 more
europepmc   +1 more source

AhR-Siglec-15 axis regulates lysosomal Ca2+ release for sonic hedgehog medulloblastoma growth via TRPML1. [PDF]

Protein Cell
Wang Z, Li S, Sun X, Wang D, Zhou Y, Zhou L, Chen J, Zhou N, Zhu Q, Liu J, Zhang G, Tong WM, Lv J, Huang B.   +13 more
europepmc   +1 more source

TPC1-dependent control of endosomal pH and transferrin uptake determines cellular iron status. [PDF]

Proc Natl Acad Sci U S A
Deutsch R, Jörs S, Klingl Y, Kudrina V, Menegaz D, Jaślan D, Serianz Z, Vogel A, Abrahamian C, Bhunia S, Tavhelidse-Suck T, Richter C, Wirth A, Urban N, Northoff B, Wilfert W, Klugbauer N, Bracher F, Keller M, Geisler F, Schaefer M, Teupser D, Holdt L, Belkaya S, Freichel M, Grimm C.   +25 more
europepmc   +1 more source

Tmem110 regulates the conformation of TRPML1 to maintain endolysosomal homeostasis and prevent mitochondrial DNA leakage and pathological self-DNA processing. [PDF]

Nat Commun
Feng Z, Pan Y, Zhou J, Chu L, Li Q, Zhang X, Wu P, Xu Z, Huang Y, Zou J, Li X, Chen X, Wang Z.   +12 more
europepmc   +1 more source