Navigating TRPML1 scholarly hotspots through a bibliometric lens / Lutfia Ilsahaida Abdul Malik, Aisyah Hasyila Jahidin and Mizaton Hazizul Hasan [PDF]
Transient Receptor Potential Mucolipin 1 (TRPML1) is a calcium-permeable cation channel predominantly localised on late endosomes and lysosomes.
Hazizul Hasan, Mizaton +2 more
core
The mucolipidosis IV Ca2+ channel TRPML1 (MCOLN1) is regulated by the TOR kinase
Autophagy is a complex pathway regulated by numerous signalling events that recycles macromolecules and may be perturbed in lysosomal storage disorders (LSDs).
Major, MB +6 more
core +1 more source
List of TRPML1-associated proteins identified by CoIP.
List of TRPML1-associated proteins identified by CoIP.
Guo-Yu Yang (1728175) +4 more
core +1 more source
Regulation of Lysosomal Adaptation to Nutrient Starvation by Lysosomal TRPML1 and PIKfyve [PDF]
, 2017 Lysosomes play an active role in sensing, signaling, and responding to nutrient availability, in addition to their well-established role in degradation.
Gao, Qiong
core
P80 | MITOCHONDRIA-LYSOSOME INTERACTIONS: EMERGING PLAYERS IN GLIOMA
European Journal of HistochemistryDespite research efforts, the results obtained in the therapy against glioma have improved but only slightly. For this reason, identifying new targets remains an important and necessary goal.
doaj +1 more source
Lysosomal activity depends on TRPML1-mediated Ca2+ release coupled to incoming vesicle fusions
The lysosomal cation channel TRPML1/MCOLN1 facilitates autophagic degradation during amino acid starvation based on studies involving long-term TRMPL1 modulation.
Bhattacharjee, Arindam +2 more
core +1 more source
The lysosomal cation channel TRPML1 regulates the oligodendrocyte cytoskeleton
Abstract Differentiating oligodendrocytes undergo dramatic morphologic alterations to transition from progenitors to mature oligodendrocytes that synthesize myelin, the lipid-rich membrane coating axons which strengthens saltatory conduction and provides metabolic support.
Lindsay K. Festa +6 more
openaire +1 more source
TRPML1 agonist ML-SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux. [PDF]
FEBS Open BioYao J +10 more
europepmc +1 more source
MODULATION OF TRPML1/TFEB PATHWAY FOR THE TREATMENT OF WILSON DISEASE
Wilson disease (WD) is an autosomal recessive disorder characterized by toxic copper accumulation in several tissues, resulting in hepatic and neurological impairment. WD is caused by mutations in the P-type ATPase copper transporting B (ATP7B) gene,
BATTIPAGLIA, MARIA
core
How to Perform a Tracer Displacement BRET Assay for the TRPML1 Ion Channel. [PDF]
Bio ProtocCunha MR +3 more
europepmc +1 more source