Results 21 to 30 of about 15,128 (217)

Capsazepine affects thermal preferences of the American cockroach (Blattodea: Blattidae)

open access: yesEuropean Journal of Entomology, 2016
Capsazepine is a competitive antagonist of capsaicin, a TRPV1 agonist responsible for the spicy taste of pepper. TRPV1 agonists and antagonists are known to affect mammalian body temperature, but their action on thermoregulation in insects is poorly ...
Justyna MALISZEWSKA, Eugenia TĘGOWSKA
doaj   +1 more source

The evolution and comparative neurobiology of endocannabinoid signalling [PDF]

open access: yes, 2012
CB(1)- and CB(2)-type cannabinoid receptors mediate effects of the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide in mammals. In canonical endocannabinoid-mediated synaptic plasticity, 2-AG is generated postsynaptically by diacylglycerol ...
Devane W. A.   +4 more
core   +1 more source

TRPV4-A Missing Link Between Mechanosensation and Immunity [PDF]

open access: yes, 2020
Transient receptor potential vanilloid-type 4 (TRPV4) cation channel is widely expressed in all tissues as well as in immune cells and its function as mechanosensitive Ca2+ channel seems to be conserved throughout all mammalian species. Of late, emerging
Kuebler, Wolfgang M., Michalick, Laura
core   +1 more source

A novel ion channel formed by interaction of TRPML3 with TRPV5. [PDF]

open access: yes, 2013
TRPML3 and TRPV5 are members of the mucolipin (TRPML) and TRPV subfamilies of transient receptor potential (TRP) cation channels. Based on sequence similarities of the pore forming regions and on structure-function evidence, we hypothesized that the pore
Becker, Lars   +4 more
core   +3 more sources

Transient Receptor Potential Vanilloid in the Brain Gliovascular Unit: Prospective Targets in Therapy

open access: yesPharmaceutics, 2021
The gliovascular unit (GVU) is composed of the brain microvascular endothelial cells forming blood–brain barrier and the neighboring surrounding “mural” cells (e.g., pericytes) and astrocytes.
Huilong Luo   +2 more
doaj   +1 more source

Stimulation of TRPV1 by green laser light [PDF]

open access: yes, 2012
Low-level laser irradiation of visible light had been introduced as a medical treatment already more than 40 years ago, but its medical application still remains controversial.
Gu, Quanbao   +3 more
core   +2 more sources

Differential Effects of TRPA and TRPV Channels on Behaviors of

open access: yesJournal of Experimental Neuroscience, 2016
TRPA and TRPV ion channels are members of the transient receptor potential (TRP) cation channel superfamily, which mediates various sensory transductions.
Jennifer Thies   +3 more
doaj   +1 more source

Multiparameter behavioral profiling reveals distinct thermal response regimes in Caenorhabditis elegans. [PDF]

open access: yes, 2012
BackgroundResponding to noxious stimuli by invoking an appropriate escape response is critical for survival of an organism. The sensations of small and large changes in temperature in most organisms have been studied separately in the context of ...
Ghosh, Rajarshi   +3 more
core   +3 more sources

TRPV1 in brain is involved in acetaminophen-induced antinociception.

open access: yesPLoS ONE, 2010
Acetaminophen, the major active metabolite of acetanilide in man, has become one of the most popular over-the-counter analgesic and antipyretic agents, consumed by millions of people daily. However, its mechanism of action is still a matter of debate. We
Christophe Mallet   +6 more
doaj   +1 more source

Top-Quark Phenomenology in Models with Bilinearly and Spontaneously Broken R-parity [PDF]

open access: yes, 1999
We study unconventional decays of the top-quark in the framework of SUSY models with spontaneously broken R-parity. In particular we discuss an effective theory which consists of the MSSM plus bilinearly broken R-parity.
Akeroyd   +10 more
core   +3 more sources

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