Results 11 to 20 of about 13,621 (198)

Lipoxygenase-derived eicosanoids in myocardial ischaemia-reperfusion injury: the role of sensory C-fibres and TRPV1 [PDF]

, 2010
PhDIt is well established that the 12-lipoxygenase (12-LOX) pathway of arachidonic acid (AA) metabolism is stimulated within the myocardium by episodes of ischaemia, and there is considerable evidence showing that eicosanoids derived via this pathway ...
Goddard, Alison
core   +4 more sources

Sertraline Alleviates Chronic Prostatitis by Regulating the TRPV1 Channel [PDF]

Journal of Inflammation Research
Yongfeng Lao,1,2 Yanan Bai,1,2 Xin Guan,1,2 Jian Wang,1,2 Yanan Wang,1,2 Rongxin Li,1,2 Yongqiang Ding,1,2 Zhilong Dong1,2 1Second Clinical Medical College, Lanzhou University, Lanzhou, Gansu, People’s Republic of China; 2Department of Urology, The ...
Lao Y, Bai Y, Guan X, Wang J, Wang Y, Li R, Ding Y, Dong Z   +7 more
doaj   +1 more source

The gut microbiota metabolite capsiate promotes Gpx4 expression by activating TRPV1 to inhibit intestinal ischemia reperfusion-induced ferroptosis

Gut Microbes, 2021
Ferroptosis, a new type of cell death has been found to aggravate intestinal ischemia/reperfusion (I/R) injury. However, little is known about the changes of gut microbiota and metabolites in intestinal I/R and the role of gut microbiota metabolites on ...
Fan Deng, Bing-Cheng Zhao, Xiao Yang, Ze-Bin Lin, Qi-Shun Sun, Yi-Fan Wang, Zheng-Zheng Yan, Wei-Feng Liu, Cai Li, Jing-Juan Hu, Ke-Xuan Liu   +10 more
doaj   +1 more source

Stimulation of TRPV1 by green laser light [PDF]

, 2012
Low-level laser irradiation of visible light had been introduced as a medical treatment already more than 40 years ago, but its medical application still remains controversial.
Wang, Lina, Schwarz, Wolfgang, Huang, Fang, Gu, Quanbao   +3 more
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Acupoint Catgut Embedding Diminishes Fibromyalgia Pain through TRPV1 in the Mouse Brain

Journal of Integrative Neuroscience, 2023
Background: Chronic pain refers to pain that persists for over three months. Chronic pain may restrict activities of daily living, including work, learning, social life, and can lead to anxiety, depression, and sleep disturbance.
Po-Chih Lai, Chia-Ming Yen, I-Han Hsiao, Yung-Hsiang Chen, Yi-Wen Lin   +4 more
doaj   +1 more source

The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis [PDF]

, 2011
Objective To assess if a coding variant in the gene encoding transient receptor potential cation channel, subfamily V, member 1 ( TRPV1 ) is associated with genetic risk of painful knee osteoarthritis (OA). Methods The Ile585Val TRPV1 variant encoded
K. R. Muir, Lories, RJ, C. Cooper, Hart, DJ, D. J. Hart, W. Zhang, Dennison, Elaine M., Arden, Nigel, S. A. Doherty, Chapman, Victoria, Cicuttini, FM, Valdes, Ana M., Doherty, Sally A., Muir, Kenneth R., Vaughn, Frances L., T. D. Spector, Zhang, Weiya, Laslett, LL, Doherty, SA, Arden, N., Lories, Rik J., Chapman, V, Jones, Graeme, A. Soni, Muir, KR, P. Leaverton, V. Chapman, Leaverton, Paul, Spector, T. D., Arden, Nigel K., Jones, G, Cicuttini, Flavia M., Wilde, Gert De, Muir, Kenneth, Doherty, M, G. Jones, Hart, Deborah J., Wheeler, M, R. A. Maciewicz, Leaverton, P, Cooper, Cyrus, N. K. Arden, Valdes, AM, G. De Wilde, Laslett, Laura L., Vaughn, FL, F. L. Vaughn, De Wilde, G, Zhang, W, A. M. Valdes, Maciewicz, Rose A., Maciewicz, RA, Spector, Tim D., Wheeler, Margaret, Dennison, EM, Spector, TD, M. Doherty, Cooper, C, R. J. Lories, M. Wheeler, Soni, Anushka, E. M. Dennison, F. M. Cicuttini, L. L. Laslett, De Wilde, Gert, Hart, Deborah J.; id_orcid, Doherty, Michael   +66 more
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Influence of TRPV1 on Thermal Nociception in Rats with Temporomandibular Joint Persistent Inflammation Evaluated by the Operant Orofacial Pain Assessment Device (OPAD)

Journal of Pain Research, 2023
Christie RA Leite-Panissi,1 Bruna B De Paula,2 John K Neubert,3 Robert M Caudle2 1Department of Psychology, School of Philosophy, Science and Literature of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil; 2Department of Oral and ...
Leite-Panissi CR, De Paula BB, Neubert JK, Caudle RM   +3 more
doaj  

Analgesic effect of dl-THP on inflammatory pain mediated by suppressing spinal TRPV1 and P2X3 receptors in rats

Frontiers in Bioscience-Landmark, 2021
Tetrahydropalmatine (dl-THP) demonstrates an analgesic effect in animal models of neuropathic and inflammatory pain, however, the underlying mechanisms of its pharmacological action within the spinal cord remains unclear. Both P2X3 receptor and TRPV1 are
Yan Wang, Rui-Rui Wang, Wei Sun, Chao Lou, Fan Yang, Ting He, Xiao-Liang Wang, Fa-Le Cao, Jun Chen   +8 more
doaj   +1 more source

Identification and Quantification of Transient Receptor Potential Vanilloid 1 (TRPV1) in Equine Articular Tissue

Animals, 2020
Joint pain and osteoarthritis (OA) are some of the most common causes of lameness in horses, and most of the available treatments focus on symptomatic relief without a disease-modifying effect.
Anne Frank Gallagher vom Braucke, Nanna Lysemose Frederiksen, Lise Charlotte Berg, Stacie Aarsvold, Felix Christoph Müller, Mikael Ploug Boesen, Casper Lindegaard   +6 more
doaj   +1 more source

Effects of different phenylcapsaicin doses on resistance training performance, muscle damage, protein breakdown, metabolic response, ratings of perceived exertion, and recovery: a randomized, triple-blinded, placebo-controlled, crossover trial

Journal of the International Society of Sports Nutrition, 2023
Background The aim of this study was to explore the effects of a low dose (LD) of 0.625 mg and a high dose (HD) of 2.5 mg of phenylcapsaicin (PC) on full squat (SQ) performance, active muscle (RPE-AM) and overall body (RPE-OB) ratings of perceived ...
Pablo Jiménez-Martínez, Pedro Jesús Cornejo-Daza, Juan Sánchez-Valdepeñas, Iván Asín-Izquierdo, Clara Cano-Castillo, Carlos Alix-Fages, Fernando Pareja-Blanco, Juan C. Colado   +7 more
doaj   +1 more source