Results 31 to 40 of about 37,042 (291)

Influence of TRPV1 on Thermal Nociception in Rats with Temporomandibular Joint Persistent Inflammation Evaluated by the Operant Orofacial Pain Assessment Device (OPAD)

Journal of Pain Research, 2023
Christie RA Leite-Panissi,1 Bruna B De Paula,2 John K Neubert,3 Robert M Caudle2 1Department of Psychology, School of Philosophy, Science and Literature of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil; 2Department of Oral and ...
Leite-Panissi CR, De Paula BB, Neubert JK, Caudle RM   +3 more
doaj  

Analgesic effect of dl-THP on inflammatory pain mediated by suppressing spinal TRPV1 and P2X3 receptors in rats

Frontiers in Bioscience-Landmark, 2021
Tetrahydropalmatine (dl-THP) demonstrates an analgesic effect in animal models of neuropathic and inflammatory pain, however, the underlying mechanisms of its pharmacological action within the spinal cord remains unclear. Both P2X3 receptor and TRPV1 are
Yan Wang, Rui-Rui Wang, Wei Sun, Chao Lou, Fan Yang, Ting He, Xiao-Liang Wang, Fa-Le Cao, Jun Chen   +8 more
doaj   +1 more source

Urothelial TRPV1: TRPV1-Reporter Mice, a Way to Clarify the Debate? [PDF]

Frontiers in Physiology, 2012
The urothelium is a complex and dynamic epithelial layer with a sensory role contributing to mechano- and chemosensation in the bladder. This primary source of sensory inputs modulates micturition via an urothelial–sensory fibers crosstalk. The communication is mediated by ATP and NO release from epithelial cells.
Mathieu eBoudes, Mathieu eBoudes, Dirk eDe Ridder   +2 more
openaire   +3 more sources

Identification and Quantification of Transient Receptor Potential Vanilloid 1 (TRPV1) in Equine Articular Tissue

Animals, 2020
Joint pain and osteoarthritis (OA) are some of the most common causes of lameness in horses, and most of the available treatments focus on symptomatic relief without a disease-modifying effect.
Anne Frank Gallagher vom Braucke, Nanna Lysemose Frederiksen, Lise Charlotte Berg, Stacie Aarsvold, Felix Christoph Müller, Mikael Ploug Boesen, Casper Lindegaard   +6 more
doaj   +1 more source

Effects of different phenylcapsaicin doses on resistance training performance, muscle damage, protein breakdown, metabolic response, ratings of perceived exertion, and recovery: a randomized, triple-blinded, placebo-controlled, crossover trial

Journal of the International Society of Sports Nutrition, 2023
Background The aim of this study was to explore the effects of a low dose (LD) of 0.625 mg and a high dose (HD) of 2.5 mg of phenylcapsaicin (PC) on full squat (SQ) performance, active muscle (RPE-AM) and overall body (RPE-OB) ratings of perceived ...
Pablo Jiménez-Martínez, Pedro Jesús Cornejo-Daza, Juan Sánchez-Valdepeñas, Iván Asín-Izquierdo, Clara Cano-Castillo, Carlos Alix-Fages, Fernando Pareja-Blanco, Juan C. Colado   +7 more
doaj   +1 more source

Targeting TRPV1 for Body Weight Control using TRPV1−/− Mice and Electroacupuncture [PDF]

Scientific Reports, 2015
AbstractObesity is a global social medical problem resulting in morbidity as high as 20–30%. Here we investigated whether the manipulation of TRPV1 can control mice body weight through electroacupuncture (EA). The results demonstrated that body weight increased with time in the control group (108.19 ± 1.31%, n = 7). The increase of mice body weight was
Monchanok Choowanthanapakorn, Kung-Wen Lu, Jun Yang, Ching-Liang Hsieh, Yi-Wen Lin   +4 more
openaire   +2 more sources

EFFECT OF EXERCISE ON TRPV1 EXPRESSION IN THE MUSCLE OF GALUR WISTAR RATS

Jurnal Kedokteran Diponegoro
Background: Exercise is an activity that induces acid generation as one of the TRPV1 stimulants. Activation of TRPV1, a pain receptor, by acid, can lead to the formation of neuropeptides such as substance P and calcitonin gene-related peptides as a cause
Hanna Goenawan, Raisa Zahra, Putri Teesa Radhiyanti, Julia Ramadhanti, Vita Murniati Tarawan, Fifi Veronica   +5 more
doaj   +1 more source

The mechanism of heat stress-induced injury in the immature oocytes of zebrafish (Danio rerio)

The Journal of Reproduction and Development
Immature zebrafish oocytes are highly susceptible to high temperatures, making it difficult to warm cryopreserved oocytes rapidly. In the present study, we aimed to investigate whether thermosensitive channels, lipid mediators, and ferroptosis ...
Yanuar ACHADRI, Nao KUWAHARA, Momoko KIMURA, Nami KANAMARU, Kazutsugu MATSUKAWA, Keisuke EDASHIGE   +5 more
doaj   +1 more source

The role of TRPV1 channels in atherosclerosis [PDF]

Channels, 2020
Transient receptor potential vanilloid subfamily member 1 (TRPV1) is a nonselective cation channel, that is mainly distributed in sensory nerve endings and can release a variety of neurotransmitters after activation. Early studies showed that it mainly conducts pain sensation, but research has demonstrated that it also plays an important role in ...
Chenyang Zhang, Lifang Ye, Qinggang Zhang, Fei Wu, Lihong Wang   +4 more
openaire   +2 more sources

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source