Results 81 to 90 of about 13,621 (198)

Toll‐Like Receptor 4 Signaling in Natural N‐Acylethanolamines and Derivative NAE‐Like Compounds: Mechanisms and Implications for Neuroimmune and Inflammatory Processes in a Systematic Search Approach

Phytotherapy Research, EarlyView.
ABSTRACT N‐acylethanolamines (NAEs) are endogenous fatty acid amides structurally related to the endocannabinoid anandamide and function as bioactive lipid mediators with broad regulatory roles in inflammation and neuroinflammation. Among pattern‐recognition receptors, Toll‐like receptor 4 (TLR4) occupies a central position in innate immune ...
Damiana Scuteri, Francesca Guida, Giacinto Bagetta, Sabatino Maione, Maria Tiziana Corasaniti, Morena Zusso   +5 more
wiley   +1 more source

TRPV1 in Dry Eye Disease

Frontiers in Bioscience-Landmark
Dry eye disease (DED) is a prevalent ophthalmic ailment with intricate pathogenesis and that occurs primarily due to various factors which affect the ocular surface.
Qingqing Gou, Zhi Song, Yu Gong, Jiawen Li   +3 more
doaj   +1 more source

Expression and functionality of TRPV1 in breast cancer cells

, 2016
Lea V Weber,1 Klaudia Al-Refae,1 Gerhard Wölk,2 Gabriele Bonatz,3 Janine Altmüller,4 Christian Becker,4 Günter Gisselmann,1 Hanns Hatt1 1Department of Cell Physiology, Ruhr‑University Bochum, Bochum, 2Herz-Jesu-Krankenhaus, Dernbach ...
Altmüller J, Weber LV, Gisselmann G, Wölk G, Hatt H, Al-Refae K, Becker C, Bonatz G   +7 more
core  

Research Progress on Upper Airway Cough Syndrome

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source

TRPV1-lineage neurons express MHCII in naïve male and female DRG, but PTX treatment only increases MHCII in TRPV1-lineage neurons in female DRG.

(A, B, E, F) Immunohistochemistry of MHCII (grayscale) and neuronal marker PGP9.5 (red) in L4 DRG tissue from TRPV1-lineage MHCII+/+ (WT), MHCII+/- (cHET) and MHCII-/- (cKO) naïve and day 14 PTX-treated female and male mice. Number = neuron diameter size,
Riley C. Cott (17935738), Emily E. Whitaker (17935732), Neal E. Mecum (17935735), Diana J. Goode (17935741)   +3 more
core   +1 more source

Where Eastern Medicine Meets Western Medicine: A World Review of the Management of Chronic Cough

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Purpose To summarize current Western and Eastern approaches to the evaluation and management of chronic cough, with particular emphasis on etiology‐directed therapy, cough hypersensitivity, behavioral interventions, neuromodulators, procedural treatments, and traditional remedies.
Thomas Zheng Jie Teng, Zhi Xuan Koh, Justin Yi Shen Lim, Kavimalar Ravi, Jin Wayne Kyler Ong, Christina Hui Lee Ng   +5 more
wiley   +1 more source

The Endocannabinoid Peptide RVD-Hemopressin Is a TRPV1 Channel Blocker

Neurotransmission is critical for brain function, allowing neurons to communicate through neurotransmitters and neuropeptides. RVD-hemopressin (RVD-Hp), a novel peptide identified in noradrenergic neurons, modulates cannabinoid receptors CB1 and CB2 ...
Ingrid Araya-Duran, Sebastián Vergara, Fernando Hinostroza, Constanza Suárez-Suárez, Valeria Márquez-Miranda, Sebastián González-Pérez, Isabel Vidal-Beltrán, Ingrid Carvacho, Hinostroza, Fernando, Márquez-Miranda, Valeria, Vergara, Sebastián, Suárez-Suárez, Constanza, Carvacho, Ingrid, Vidal-Beltrán, Isabel, González-Pérez, Sebastián, Araya-Duran, Ingrid   +15 more
core   +2 more sources

Capsaicin modulates Akkermansia muciniphila abundance by enhancing MUCIN2 levels in mice fed with high-fat diets

Food & Nutrition Research
Extensive research has been conducted to investigate the impact of capsaicin (CAP) on lipid metabolism, focusing specifically on its interaction with the vanilloid subtype 1 (TRPV1) ion channel.
Ting Gong, Yujing Zhou, Qinhong Shi, Yanyan Li, Haizhu Wang, Min Zhang, Linzheng Liao   +6 more
doaj   +1 more source

Decreased expression of TRPV1 in renal cell carcinoma: association with tumor Fuhrman grades and histopathological subtypes

, 2018
Yong-Yang Wu,1 Xin-Yu Liu,2 De-Xiang Zhuo,1 Huai-Bin Huang,1 Fa-Biao Zhang,1 Shang-Fan Liao1 1Department of Urology, Affiliated Sanming First Hospital, Fujian Medical University, Sanming, Fujian 365100, China; 2State Key Laboratory of Biotherapy and ...
Zhuo DX, Liu XY, Zhang FB, Liao SF, Huang HB, Wu YY   +5 more
core  

Colocalization of mSlo1 and TRPV1 in HEK293 cells.

, 2013
A, Surface expression of mSlo1 and TRPV1. HEK293 cells were cotransfected with mSlo1-TagGFP (green) and TRPV1-myc (red). Confocal images of mSlo1-TagGFP (left panel) and TRPV1-myc (middle panel) have clearly green and red edges, respectively, and the ...
Ying Wu (19057), Beiying Liu (471709), Feng Qin (133395), Wenjuan Kong (471708), Yuexuan Zhang (471710), Yongfeng Liu (413340), Panpan Hou (471706), Jing Yao (169854), Zonghe Yan (471707), Jiuping Ding (45929), Xia Li (14984)   +10 more
core   +1 more source