Results 91 to 100 of about 13,621 (198)
Phosphoinositide 3-Kinase Binds to TRPV1 and Mediates NGF-stimulated TRPV1 Trafficking to the Plasma Membrane [PDF]
, 2006 Sensitization of the pain-transducing ion channel TRPV1 underlies thermal hyperalgesia by proalgesic agents such as nerve growth factor (NGF). The currently accepted model is that the NGF-mediated increase in TRPV1 function during hyperalgesia utilizes ...
Gordon, Sharona E +9 more
core +1 more source
Integrative Zoology, EarlyView.This study integrates genomics and landscape genetics to analyze African goat environmental adaptation. Analyzing 1591 samples, it finds population structure differentiates geographically into four groups, with gene flow between wild Yura goats and North Africans.
Weifeng Peng +19 more
wiley +1 more source
Molecular Pain, 2018 Background We have previously reported that histamine-induced pruritus was attenuated in toll-like receptor 4 (TLR4) knockout mice due to decreased transient receptor potential V1 (TRPV1) sensitivity.
Hyunjung Min +10 more
doaj +1 more source
Mechanosensitivity of gastric vagal afferents in TRPV1+/+ and-/- mice.
, 2015 Stimulus response functions of tension-sensitive (A) and mucosal (B) gastric vagal afferents from (i) TRPV1+/+ and (ii) TRPV1-/- mice fed a SLD (● or ○, N = 10) or HFD (■ or □, N = 10 ...
Tracey A. O’Donnell (784636) +7 more
core +1 more source
Geographical Variation in Thermal Adaptation of the Asiatic Toad (Bufo gargarizans)
Integrative Zoology, EarlyView.Northern and southern populations of Bufo gargarizans exhibit coordinated divergence in thermal preference, resting metabolic rate, and TRPM4 temperature sensitivity along a climatic gradient. ABSTRACT Thermal adaptation in animals can manifest in multiple dimensions, yet few studies have integrated behavioral, physiological, and molecular perspectives
Longcheng Fan, Yonghua Wu
wiley +1 more source
The role of TASK-1 and TRPV1 channels in the male reproductive system
Journal of Animal Reproduction and BiotechnologyThe mammalian testis is a highly organized organ essential for male reproduction. Its structure comprises seminiferous tubules lined with Sertoli cells, which support spermatogenesis, surrounded by peritubular myoid cells.
Dawon Kang, Eun-A Ko
doaj +1 more source
TRPV1 gates tissue access and sustains pathogenicity in autoimmune encephalitis.
, 2013 Multiple sclerosis (MS) is a chronic progressive, demyelinating condition whose therapeutic needs are unmet, and whose pathoetiology is elusive. We report that transient receptor potential vanilloid-1 (TRPV1) expressed in a major sensory neuron subset ...
Geoffrey Paltser +16 more
core +1 more source
Surgical Management of Non‐Allergic Rhinitis—An EAACI Task Force Position Paper
Allergy, EarlyView.ABSTRACT Non‐allergic rhinitis is a frequent yet underdiagnosed cause of chronic nasal symptoms, including nasal congestion, rhinorrhoea, and upper airway hyperreactivity. Its pathophysiology involves neurogenic dysregulation, leading to excessive mucus production and vasodilation.
Marie Lundberg +18 more
wiley +1 more source
TRPV1 and Piezo: the 2021 Nobel Prize in Physiology or Medicine
IUCrJ, 2022 Yifan Cheng
doaj +1 more source
TRPV1 enhances the afferent response to P2X receptor activation in the mouse urinary bladder
Scientific Reports, 2018 Both TRPV1 and P2X receptors present on bladder sensory nerve fibres have been implicated in mechanosensation during bladder filling. The aim of this study was to determine possible interactions between these receptors in modulating afferent nerve ...
Luke Grundy +4 more
doaj +1 more source