Results 111 to 120 of about 37,042 (291)
Phytotherapy Research, EarlyView.Functional dyspepsia involves duodenal barrier dysfunction, low‐grade immune activation and altered neuroimmune signalling. Various plant‐derived bioactives may modulate PPAR signalling, reduce inflammatory and oxidative stress, and support epithelial, immune, metabolic, and sensory homeostasis.
Irene Palenca +5 more
wiley +1 more source
Food & Nutrition ResearchExtensive research has been conducted to investigate the impact of capsaicin (CAP) on lipid metabolism, focusing specifically on its interaction with the vanilloid subtype 1 (TRPV1) ion channel.
Ting Gong +6 more
doaj +1 more source
Exploring functional roles of TRPV1 intracellular domains with unstructured peptide-insertion screening [PDF]
, 2016 TRPV1 is a polymodal nociceptor for diverse physical and chemical stimuli that interact with different parts of the channel protein. Recent cryo-EM studies revealed detailed channel structures, opening the door for mapping structural elements mediating ...
Ma, Linlin +3 more
core +1 more source
Phosphoinositide regulation of TRPV1 revisited [PDF]
Pflügers Archiv - European Journal of Physiology, 2015 The heat- and capsaicin-sensitive transient receptor potential vanilloid 1 ion channel (TRPV1) is regulated by plasma membrane phosphoinositides. The effects of these lipids on this channel have been controversial. Recent articles re-ignited the debate and also offered resolution to place some of the data in a coherent picture.
openaire +2 more sources
Research Progress on Upper Airway Cough Syndrome
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley +1 more source
Molecular Pain, 2018 Background We have previously reported that histamine-induced pruritus was attenuated in toll-like receptor 4 (TLR4) knockout mice due to decreased transient receptor potential V1 (TRPV1) sensitivity.
Hyunjung Min +10 more
doaj +1 more source
Expression and functionality of TRPV1 in breast cancer cells
, 2016 Lea V Weber,1 Klaudia Al-Refae,1 Gerhard Wölk,2 Gabriele Bonatz,3 Janine Altmüller,4 Christian Becker,4 Günter Gisselmann,1 Hanns Hatt1 1Department of Cell Physiology, Ruhr‑University Bochum, Bochum, 2Herz-Jesu-Krankenhaus, Dernbach ...
Altmüller J +7 more
core
Integrative Zoology, EarlyView.This study integrates genomics and landscape genetics to analyze African goat environmental adaptation. Analyzing 1591 samples, it finds population structure differentiates geographically into four groups, with gene flow between wild Yura goats and North Africans.
Weifeng Peng +19 more
wiley +1 more source
The role of TASK-1 and TRPV1 channels in the male reproductive system
Journal of Animal Reproduction and BiotechnologyThe mammalian testis is a highly organized organ essential for male reproduction. Its structure comprises seminiferous tubules lined with Sertoli cells, which support spermatogenesis, surrounded by peritubular myoid cells.
Dawon Kang, Eun-A Ko
doaj +1 more source
TRPV1 enhances the afferent response to P2X receptor activation in the mouse urinary bladder
Scientific Reports, 2018 Both TRPV1 and P2X receptors present on bladder sensory nerve fibres have been implicated in mechanosensation during bladder filling. The aim of this study was to determine possible interactions between these receptors in modulating afferent nerve ...
Luke Grundy +4 more
doaj +1 more source