Results 121 to 130 of about 37,042 (291)

A vaszkuláris vanilloid receptor farmakológiai vizsgálata

, 2010
A vanilloid receptor (TRPV1) egy kalcium ionokat is átengedő nem specifikus kation csatorna. A TRPV1 elsősorban a fájdalmat közvetítő nociceptorokon, a primer szenzoros neuronokon expresszálódik.
Csató, Viktória
core  

Geographical Variation in Thermal Adaptation of the Asiatic Toad (Bufo gargarizans)

Integrative Zoology, EarlyView.
Northern and southern populations of Bufo gargarizans exhibit coordinated divergence in thermal preference, resting metabolic rate, and TRPM4 temperature sensitivity along a climatic gradient. ABSTRACT Thermal adaptation in animals can manifest in multiple dimensions, yet few studies have integrated behavioral, physiological, and molecular perspectives
Longcheng Fan, Yonghua Wu
wiley   +1 more source

TRPV1 and Piezo: the 2021 Nobel Prize in Physiology or Medicine

IUCrJ, 2022
Yifan Cheng
doaj   +1 more source

Transient Receptor Potential Vanilloid 1 Regulates Mitochondrial Membrane Potential and Myocardial Reperfusion Injury

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
Background The transient receptor potential vanilloid 1 (TRPV1) mediates cellular responses to pain, heat, or noxious stimuli by calcium influx; however, the cellular localization and function of TRPV1 in the cardiomyocyte is largely unknown.
Carl M. Hurt, Yao Lu, Creed M. Stary, Honit Piplani, Bryce A. Small, Travis J. Urban, Nir Qvit, Garrett J. Gross, Daria Mochly‐Rosen, Eric R. Gross   +9 more
doaj   +1 more source

Surgical Management of Non‐Allergic Rhinitis—An EAACI Task Force Position Paper

Allergy, EarlyView.
ABSTRACT Non‐allergic rhinitis is a frequent yet underdiagnosed cause of chronic nasal symptoms, including nasal congestion, rhinorrhoea, and upper airway hyperreactivity. Its pathophysiology involves neurogenic dysregulation, leading to excessive mucus production and vasodilation.
Marie Lundberg, Julie van Waterschoot, Mathilde Moyaert, Adam Chaker, Philippe Gevaert, Jan Hagemann, Valérie Hox, Maarten Kleijwegt, Ludger Klimek, Devyani Lal, Juan Maza‐Solano, Oliver Pfaar, Fabio Simon Ryser, Michele Shiappoli, Diana Silva, Sanna Toppila‐Salmi, Johanna Wikstén, Sietze Reitsma, Laura Van Gerven   +18 more
wiley   +1 more source

TRPV1 Inhibits Ferroptosis and Mitophagy to Alleviate Heart Failure by Activating SFXN2

Frontiers in Bioscience-Landmark
Background: Heart failure (HF) continues to represent a significant global public health concern. Transient receptor potential cation channel subfamily V member 1 (TRPV1) is a calcium-permeable channel that has been linked to cardiac ...
Pan Liu, Shiguang Wang, Liya Li, Ruihua Li, Minming Fan, Jingjing Kong, Bing Gao, Jing Wang, Ran Xia   +8 more
doaj   +1 more source

Decreased expression of TRPV1 in renal cell carcinoma: association with tumor Fuhrman grades and histopathological subtypes

, 2018
Yong-Yang Wu,1 Xin-Yu Liu,2 De-Xiang Zhuo,1 Huai-Bin Huang,1 Fa-Biao Zhang,1 Shang-Fan Liao1 1Department of Urology, Affiliated Sanming First Hospital, Fujian Medical University, Sanming, Fujian 365100, China; 2State Key Laboratory of Biotherapy and ...
Zhuo DX, Liu XY, Zhang FB, Liao SF, Huang HB, Wu YY   +5 more
core  

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

TRPV1 and blockers

, 2016
Biophysical description of block by quaternary ...
openaire   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source