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TRP Channels as Therapeutic Targets in Kidney Disease and Hypertension
, 2013 The Drosophila trp homologue Transient Receptor Potential (TRP) cation channels are ubiquitous in most species and cell types. The functional TRP subclasses TRPC, TRPV and TRPP gate Ca2+ and other cations in mammalian tissues, including the kidney. It is
Giorgio Punzo +2 more
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Sex-related and temperature-dependent responses of transient receptor potential cation channel subfamily vanilloid (TRPVs) genes in chub mackerel.identifier:oai:t2r2.star.titech.ac.jp ...
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Characterization of temperature-sensitive Transient Receptor Potential Cation Channel Subfamily Vanilloid (TRPV) 1 and its modulation of fshb expression in chub mackerel (Scomber japonicus)identifier:oai:t2r2.star.titech.ac.jp ...
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, 2011 For all organisms, the ability to sense and react to noxious environments is fundamental to their survival. For multi-celled organisms this process generally involves a nervous system and an extensive network of signal transduction pathways.
Lindy, Amanda Sue
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Capsaicin protects neuromuscular junctions from the inhibitory effects of botulinum neurotoxin A
, 2008 Within 24 hrs after injecting botulinum neurotoxin A (BoNT/A) into the hindlimb, mice lost the toe spread reflex and developed progressive muscle weakness. At the same time, the compound muscle action potential amplitude decreased. Injection of capsaicin
Carmen Garcia +5 more
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Hearing Research, 2005
The transient receptor potential cation channel subfamily V (TRPV) is a non-specific cation ion channel receptor family that is gated by heat, protons, low extracellular osmolarity and arachidonic acid derivatives. Since some of these endogenous agonists of TRPV receptors are reactive oxygen intermediates produced by lipoxygenases, it has been ...
Tadashi Kitahara +2 more
exaly +3 more sources
The transient receptor potential cation channel subfamily V (TRPV) is a non-specific cation ion channel receptor family that is gated by heat, protons, low extracellular osmolarity and arachidonic acid derivatives. Since some of these endogenous agonists of TRPV receptors are reactive oxygen intermediates produced by lipoxygenases, it has been ...
Tadashi Kitahara +2 more
exaly +3 more sources
TRPC and TRPV Channels’ Role in Vascular Remodeling and Disease [PDF]
International Journal of Molecular Sciences, 2020 Transient receptor potentials (TRPs) are non-selective cation channels that are widely expressed in vascular beds. They contribute to the Ca2+ influx evoked by a wide spectrum of chemical and physical stimuli, both in endothelial and vascular smooth ...
Marta Martín-Bórnez +2 more
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Transient receptor potential cation channel subfamily V (TRPV) and its importance in asthma.
European Journal of Pharmacology, 2022Transient receptor potential (TRP) ion channels play critical roles in physiological and pathological conditions. Increasing evidence has unveiled the contribution of TRP vanilloid (TRPV) family in the development of asthma. The TRPV family is a group (TRPV1-TRPV6) of polymodal channels capable of sensing thermal, acidic, mechanical stress, and osmotic
Jorge, Reyes-García +2 more
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