Results 81 to 90 of about 1,008,370 (159)

Role of TRPV receptors in respiratory diseases [PDF]

, 2007
Transient receptor potential vanilloid type channels (TRPVs) are expressed in several cell types in human and animal lungs. Increasing evidence has demonstrated important roles of these cation channels, particularly TRPV1 and TRPV4, in the regulation of ...
Lee, Lu-Yuan, Lu-Yuan Lee, Yanlin Jia, Jia, Yanlin   +3 more
core   +1 more source

The Thoracic Lymphatic Vasculature: Interorgan Strategies to Achieve an Optimal Tissue Function

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
In the thorax, organ‐specific features such as stomata and submesothelial lacunae, pulmonary perivascular and peribronchial vessels, and subepicardial lymphatic network allow the thoracic lymphatics to perform as a dynamically regulated system able to exploit local mechanical forces and tissue‐specific architecture to maintain fluid and solute ...
Daniela Negrini, Eleonora Solari, Cristiana Marcozzi, Andrea Moriondo   +3 more
wiley   +1 more source

Structural Analyses of the Ankyrin Repeat Domain of TRPV6 and Related TRPV Ion Channels

, 2013
Transient receptor potential (TRP) proteins are cation channels composed of a transmembrane domain flanked by large N- and C-terminal cytoplasmic domains.
Huang, Robert J., Wang, Ruiqi Rachel, Phelps, Christopher B., Gaudet, Rachelle, Lishko, Polina V.   +4 more
core   +1 more source

Intravesical Cannabidiol for Inflammation and Pain in Interstitial Cystitis/Bladder Pain Syndrome via TLR4/NF-κB and TRPV1 Modulation

The World Journal of Men's Health
Purpose: This study explored the anti-inflammatory and analgesic mechanisms of intravesical cannabidiol (CBD) in cyclophosphamide (CYP)-induced interstitial cystitis/bladder pain syndrome (IC/BPS) rats. Materials and Methods: Female Sprague-Dawley rats
Jun Jie Piao, Soomin Kim, Hwa Jong Lee, Guan Qun Zhu, Kyung-Hwa Jeon, Sang-Hyuck Park, Rui-Li Guan, Wen Jie Tian, Zhong Cheng Xin, Sae Woong Kim, Woong Jin Bae   +10 more
doaj   +1 more source

Bidirectional Roles of TRPV1 in a Latent Sensitization Model of Myofascial Low Back Pain

European Journal of Pain, Volume 30, Issue 4, April 2026.
ABSTRACT Introduction Chronic primary low back pain (cpLBP) is a global health concern with poorly understood pathomechanisms, potentially involving spinal sensitization. The capsaicin receptor TRPV1 plays a crucial role in sensitization across pain models.
Vivian Blechschmidt, Bastian Schlickenrieder, Jonathan R. Husk, Ulrich Hoheisel, Handan Mörz, Rolf‐Detlef Treede, Wolfgang Greffrath   +6 more
wiley   +1 more source

Transient receptor potential cation channel subfamily V and breast cancer

, 2020
Transient receptor potential cation channel subfamily V (TRPV) channels play important roles in a variety of cellular processes. One example includes the sensory role of TRPV1 that is sensitive to elevated temperatures and acidic environments and is ...
Monteith, Gregory R., So, Choon Leng, Milevskiy, Michael J. G.   +2 more
core   +1 more source

Inhibition of native TRPC6 channel activity by phosphatidylinositol 4,5-bisphosphate in mesenteric artery myocytes [PDF]

, 2008
The present work investigates the effect of phosphatidylinositol-4,5-bisphosphate (PIP2) on native TRPC6 channel activity in freshly dispersed rabbit mesenteric artery myocytes using patch clamp recording and co-immunoprecipitation methods.
Saleh, Sohag N., Albert, Anthony P., Large, William A., Large, WA, Saleh, SN, Albert, AP   +5 more
core   +1 more source

Editorial: Vulvodynia and beyond: innate immune sensing, microbes, inflammation, and chronic pain

Frontiers in Cellular and Infection Microbiology, 2023
Megan L. Falsetta, Megan L. Falsetta
doaj   +1 more source

Structural Analyses of the Ankyrin Repeat Domain of TRPV6 and Related TRPV Ion Channels^†,‡

, 2016
Transient receptor potential (TRP) proteins are cation channels composed of a transmembrane domain flanked by large N- and C-terminal cytoplasmic domains.
Rachelle Gaudet (1287813), Polina V. Lishko (1277544), Robert J. Huang (2452591), Christopher B. Phelps (2452597), Ruiqi R. Wang (2452594)   +4 more
core   +1 more source

Identification of transient receptor potential channel genes from the swimming crab, Portunus Trituberculatus, and their expression profiles under acute temperature stress

BMC Genomics
Background Temperature is an important environment factor that is critical to the survival and growth of crustaceans. However, the mechanisms by which crustaceans detect changes in temperature are still unclear.
Yichen Qian, Qiaoling Yu, Jun Zhang, Yaoyao Han, Xi Xie, Dongfa Zhu   +5 more
doaj   +1 more source