Results 71 to 80 of about 238 (118)

Local Anesthetics in Cancer: Mechanisms and Translational Perspectives

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang, Tu Huang, Yi‐hang Hao, Min Zheng, Xin‐hua Liang   +4 more
wiley   +1 more source

Regulation Mechanisms of TRPV Channels by Protein Kinase C [PDF]

, 2007
総合研究大学院大学博士（理学）TRP (transient receptor potential) channels were first described in Drosophila, where photoreceptors carrying trp gene mutations exhibited an abnormal transient responsiveness to continuous light.
東, 智広, HIGASHI, Tomohiro, ヒガシ, トモヒロ   +2 more
core  

Transient receptor potential cation channels in disease

, 2007
The transient receptor potential (TRP) superfamily consists of a large number of cation channels that are mostly permeable to both monovalent and divalent cations.
Owsianik, Grzegorz, Voets, Thomas, Nilius, Bernd, Peters, John A.   +3 more
core   +1 more source

TRPV channels mediate temperature-sensing in human corneal endothelial cells

, 2010
The physiology and transparency of the cornea are dependent on corneal endothelial function. the role of temperature sensitive ion channels in maintaining such activity is unknown.
Mergler, Stefan, Valtink, Monika, Lindemann, Dirk, Reinach, Peter S., Pleyer, Uwe, Engelmann, Katrin, Coulson-Thomas, Vivien Jane [UNIFESP]   +6 more
core   +1 more source

Editorial: Vulvodynia and beyond: innate immune sensing, microbes, inflammation, and chronic pain

Frontiers in Cellular and Infection Microbiology, 2023
Megan L. Falsetta, Megan L. Falsetta
doaj   +1 more source

Identification of transient receptor potential channel genes from the swimming crab, Portunus Trituberculatus, and their expression profiles under acute temperature stress

BMC Genomics
Background Temperature is an important environment factor that is critical to the survival and growth of crustaceans. However, the mechanisms by which crustaceans detect changes in temperature are still unclear.
Yichen Qian, Qiaoling Yu, Jun Zhang, Yaoyao Han, Xi Xie, Dongfa Zhu   +5 more
doaj   +1 more source

Transient receptor potential channels in Flaviviridae infection: A comprehensive review

Channels
Diseases caused by Flaviviridae viruses exert profound global health and economic burdens due to their high incidence and associated mortality. Infection by the Flaviviridae family often leads to severe acute or chronic illnesses, including hemorrhagic ...
Fuchun Jiang, Xiaoqiang Yao, Chang-Bo Zheng   +2 more
doaj   +1 more source

Direct proton conductance through the TRPV1 pore and multimerization of TRPV channel subunits

, 2005
0\. Titelblatt und Inhaltsverzeichnis 1\. Einleitung 2\. Zielsetzung 3\. Material und Methoden 4\. Ergebnisse 5\. Diskussion 6\. Zusammenfassung 7\. Referenzen 8\.
Hellwig, Nicole Barbara
core   +1 more source

Anàlisi genètica i funcional de la migranya hemiplègica i la migranya comuna [PDF]

, 2011
[cat] Aquesta tesi es centra en la genètica de la migranya. La migranya comuna és un trastorn neurològic caracteritzat per episodis recurrents de mal de cap.
Carreño, Oriel
core  

TRP channels: an overview.

, 2005
Udgivelsesdato: null-nullThe TRP ("transient receptor potential") family of ion channels now comprises more than 30 cation channels, most of which are permeable for Ca2+, and some also for Mg2+.
Owsianik, Grzegorz, Nilius, Bernd, Pedersen, Stine Falsig   +2 more
core   +1 more source