Results 91 to 100 of about 804,478 (143)

DEG/ENaC but Not TRP Channels Are the Major Mechanoelectrical Transduction Channels in a C. elegans Nociceptor [PDF]

, 2011
SummaryMany nociceptors detect mechanical cues, but the ion channels responsible for mechanotransduction in these sensory neurons remain obscure. Using in vivo recordings and genetic dissection, we identified the DEG/ENaC protein, DEG-1, as the major ...
Montoya, Misty, Tim Hau-Chen Lee, Shana L. Geffeney, Snetu Karania, Geffeney, Shana L., Doll, Joseph C., Arman M. Garakani, Miriam B. Goodman, Pruitt, Beth L., Juan G. Cueva, Joseph C. Doll, Karania, Snetu, Beth L. Pruitt, Cueva, Juan G., Garakani, Arman M., Lee, Tim Hau-Chen, Goodman, Miriam B., Glauser, Dominique A., Dominique A. Glauser, Misty Montoya   +19 more
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TRP Channels in Angiogenesis and Other Endothelial Functions

Frontiers in Physiology, 2018
Angiogenesis is the growth of blood vessels mediated by proliferation, migration, and spatial organization of endothelial cells. This mechanism is regulated by a balance between stimulatory and inhibitory factors.
Tarik Smani, Tarik Smani, Luis J. Gómez, Sergio Regodon, Geoffrey E. Woodard, Geraldine Siegfried, Abdel-Majid Khatib, Juan A. Rosado   +7 more
doaj   +1 more source

Intraflagellar Transport Is Required for the Vectorial Movement of TRPV Channels in the Ciliary Membrane [PDF]

, 2005
SummaryThe membranes of all eukaryotic motile (9 + 2) and immotile primary (9 + 0) cilia harbor channels and receptors involved in sensory transduction (reviewed by [1]).
Burnette, Dylan T., Bae, Young-Kyung, Forscher, Paul, Rosenbaum, Joel L., Qin, Hongmin, Barr, Maureen M.   +5 more
core   +1 more source

Regulation Mechanisms of TRPV Channels by Protein Kinase C [PDF]

, 2007
総合研究大学院大学博士（理学）TRP (transient receptor potential) channels were first described in Drosophila, where photoreceptors carrying trp gene mutations exhibited an abnormal transient responsiveness to continuous light.
東, 智広, HIGASHI, Tomohiro, ヒガシ, トモヒロ   +2 more
core  

Ca²⁺-permeable TRPV and TRPC channels account for sustained elevation of [Ca²⁺]_i in response to ATP.

, 2013
The average time course of relative changes in ΔF340/F380 in response to 2 min ATP applications (shown with gray bar on the top) for individual cells of ASDN in the absence and presence (shown with black bar) of a TRPC channels inhibitor, BTP2 (A) and a ...
Min Jin (333526), Roger G. O'Neil (346763), Oleg Zaika (53586), Mykola Mamenko (346760), Oleh Pochynyuk (346764)   +4 more
core   +1 more source

Polymodal Transient Receptor Potential Vanilloid (TRPV) Ion Channels in Chondrogenic Cells [PDF]

, 2015
Mature and developing chondrocytes exist in a microenvironment where mechanical load, changes of temperature, osmolarity and acidic pH may influence cellular metabolism.
Földvári, Zs., Csaba Matta, Dobrosi, N., Juhász, T., Éva Katona, Gergely, P., Pál Gergely, Tamás Juhász, Ádám Takács, Zsofia Foldvari, Katona, É., Csilla Somogyi, Tibor Hajdú, Nóra Dobrosi, Somogyi, Cs., Róza Zákány, Zákány, R., Matta, Cs., Takács, R. Á., Hajdu, T.   +19 more
core   +1 more source

Specific Polyunsaturated Fatty Acids Drive TRPV-Dependent Sensory Signaling In Vivo [PDF]

, 2004
A variety of lipid and lipid-derived molecules can modulate TRP cation channel activity, but the identity of the lipids that affect TRP channel function in vivo is unknown. Here, we use genetic and behavioral analysis in the nematode C.
Kahn-Kirby, Amanda H, Jami L.M. Dantzker, William R. Schafer, Apicella, Alfonso J, Schafer, William R., Browse, John, Alfonso J. Apicella, Cornelia I. Bargmann, Watts, Jennifer L, Jennifer L. Watts, Apicella, Alfonso J., Watts, Jennifer L., Bargmann, Cornelia I, Schafer, William R, Dantzker, Jami L.M, Amanda H. Kahn-Kirby, Dantzker, Jami L.M., John Browse, Kahn-Kirby, Amanda H., Bargmann, Cornelia I.   +19 more
core   +1 more source

The role of transient receptor potential channels in chronic kidney disease-mineral and bone disorder

Frontiers in Pharmacology
Chronic kidney disease (CKD) represents a major global health challenge, frequently resulting in the development of chronic kidney disease-mineral and bone disorder (CKD-MBD). Transient receptor potential (TRP) channels, particularly the TRPV (vanilloid),
Lerong Zhang, Lerong Zhang, Penghao Xu, Penghao Xu, Lele Hao, Lele Hao, Lingling Wang, Yunkai Xu, Yunkai Xu, Chen Jiang, Chen Jiang   +10 more
doaj   +1 more source

Functions of TRPs in retinal tissue in physiological and pathological conditions

Frontiers in Molecular Neuroscience
The Transient Receptor Potential (TRP) constitutes a family of channels subdivided into seven subfamilies: Ankyrin (TRPA), Canonical (TRPC), Melastatin (TRPM), Mucolipin (TRPML), no-mechano-potential C (TRPN), Polycystic (TRPP), and Vanilloid (TRPV ...
Thaianne Hanah Oliveira do Nascimento, Danniel Pereira-Figueiredo, Louise Veroneze, Amanda Alves Nascimento, Francesco De Logu, Romina Nassini, Paula Campello-Costa, Adriana da Cunha Faria-Melibeu, Daniel Souza Monteiro de Araújo, Karin Costa Calaza, Karin Costa Calaza   +10 more
doaj   +1 more source

Effects of Osmotic Pressures and TRPV-4 Inhibitors on Calcium Levels in Dorsal Root Ganglion Cells [PDF]

, 2019
Cancer is a prevalent disease that has been researched for many years to find a cure. A potential focus is the popular chemotherapeutic, paclitaxel (PTX), which has been known to treat a number of metastatic cancers with high efficacy.
Chen, Albert Deng
core   +1 more source