Results 81 to 90 of about 804,478 (143)

Table_1_Pan-Cancer Analysis Reveals Genomic and Clinical Characteristics of TRPV Channel-Related Genes.xlsx

open access: yes, 2022
BackgroundTransient Receptor Potential channels (TRPs), a class of ion channels, were first described two decades ago. Many TRP family members are major participants in nociception and integration of heat and pain signals.
Guanghao Li (2888015)   +9 more
core   +1 more source

The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation

open access: yesInternational Endodontic Journal, Volume 59, Issue 10, Page 2028-2045, October 2026.
ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli   +3 more
wiley   +1 more source

Cancer‐related pain: A bidirectional modulator of cancer progression

open access: yesClinical and Translational Medicine, Volume 16, Issue 9, September 2026.
CRP and tumour progression engage in a dynamic, bidirectional circuit mediated by multiple mechanisms involving neuroimmunology and cancer ‐neuroscience. Analgesic interventions may affect tumour progression, while anticancer therapies can influence pain. Targeting pain in cancer may have promising therapeutic value in cancer progression.
Junzhe He   +5 more
wiley   +1 more source

Structural Analyses of the Ankyrin Repeat Domain of TRPV6 and Related TRPV Ion Channels†,‡

open access: yes, 2016
Transient receptor potential (TRP) proteins are cation channels composed of a transmembrane domain flanked by large N- and C-terminal cytoplasmic domains.
Rachelle Gaudet (1287813)   +4 more
core   +1 more source

channels: Unveiling a functionally diverse group of ion channels [PDF]

open access: yes, 2020
Transient receptor potential vanilloid (TRPV) channels are part of the superfamily of TRP ion channels and play important roles in widespread physiological processes including both neuronal and non-neuronal pathways.
Leanne de Jager   +7 more
core   +1 more source

Hell's Itch: A Self‐Case Report

open access: yesJEADV Clinical Practice, Volume 5, Issue 3, Page 982-985, September 2026.
ABSTRACT Hell's itch is a severely distressing dermatological condition characterized by the onset of incessant itching and intolerable pain 2–3 days post‐sunburn. It is underdiagnosed and underreported, and no definitive management framework has yet been developed.
Kai Peter Moors, Willem I. Visser
wiley   +1 more source

Image_4_Pan-Cancer Analysis Reveals Genomic and Clinical Characteristics of TRPV Channel-Related Genes.tif

open access: yes, 2022
BackgroundTransient Receptor Potential channels (TRPs), a class of ion channels, were first described two decades ago. Many TRP family members are major participants in nociception and integration of heat and pain signals.
Guanghao Li (2888015)   +9 more
core   +1 more source

Image_5_Pan-Cancer Analysis Reveals Genomic and Clinical Characteristics of TRPV Channel-Related Genes.tif

open access: yes, 2022
BackgroundTransient Receptor Potential channels (TRPs), a class of ion channels, were first described two decades ago. Many TRP family members are major participants in nociception and integration of heat and pain signals.
Guanghao Li (2888015)   +9 more
core   +1 more source

Thermosensory TRPV Heterotetramers Drive Seasonal Polyphenism: Molecular Basis of CcIav/CcNan‐PKCα‐AKH/AKHR Signaling in Pear Psyllid Morph Transition

open access: yesAdvanced Science
Temperature critically governs seasonal polyphenism, shaping species distribution and invasion dynamics. Although vanilloid‐type transient receptor potential (TRPV) channels are conserved thermal sensors, their mechanistic role in orchestrating seasonal ...
Jianying Li   +6 more
doaj   +1 more source

Cytosolic domains of TRPV channels.

open access: yes, 2014
A. Conservation plot for the TRPV1 N-terminus (surface representation) and C-terminus (ribbon representation) interaction region. The residues involved in the MPD and TRP box interaction have been selected using a 5Å threshold.
Alex Perálvarez-Marín (145663)   +1 more
core   +1 more source

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