Differential Effects of TRPA and TRPV Channels on Behaviors of
Journal of Experimental Neuroscience, 2016 TRPA and TRPV ion channels are members of the transient receptor potential (TRP) cation channel superfamily, which mediates various sensory transductions.
Jennifer Thies +3 more
doaj +1 more source
Cell Reports, 2020 Summary: One approach to magnetogenetics uses radiofrequency (RF) waves to activate transient receptor potential channels (TRPV1 and TRPV4) that are coupled to cellular ferritins.
Miriam Hernández-Morales +4 more
doaj +1 more source
A molecular determinant of phosphoinositide affinity in mammalian TRPV channels. [PDF]
Sci Rep, 2016 Phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2 ] is an important cofactor for ion channels. Affinity for this lipid is a major determinant of channel inhibition by depletion of PI(4,5)P2 upon phospholipase C (PLC) activation. Little is known about what
Velisetty P +6 more
europepmc +2 more sources
Enhancement of immune cytokines and splenic CD4+ T cells by electroacupuncture at ST36 acupoint of SD rats. [PDF]
PLoS ONE, 2017 Electroacupuncture at the ST36 acupoint can enhance the body's immune function. However, the mechanism for this enhancement has not been fully described.
Longyun Chen +7 more
doaj +1 more source
The expression of TRPV channels, prostaglandin E2 and pro-inflammatory cytokines during behavioural fever in fish [PDF]
, 2018 A fever, or increased body temperature, is a symptom of inflammation, which is a complex defence reaction of the organism to pathogenic infections. After pathogens enter the body, immune cells secrete a number of agents, the functions of which stimulate ...
Diego Crespo +23 more
core +1 more source
Expression of Transient Receptor Potential Vanilloid (TRPV) channels in different passages of articular chondrocytes. [PDF]
, 2017 Ion channels play important roles in chondrocyte mechanotransduction. The transient receptor potential vanilloid (TRPV) subfamily of ion channels consists of six members.
Hdud, IM +4 more
core +3 more sources
TRPV channels activation induces cell death in Human Pancreatic Ductal Adenocarcinoma cell lines
, 2022 Introduction Pancreatic Ductal Adenocarcinoma is one of the most aggressive and lethal malignancy. The main therapeutic strategy is surgical resection followed by adjuvant chemotherapy, but only 10-20-% of patients have a resectable form, while if it is
G. Santoni +7 more
core +1 more source
Frontiers in Immunology, 2022 BackgroundThe transient receptor potential vanilloid (TRPV) channels family, TRPV1-6, has been identified to profoundly affect a wide spectrum of pathological processes in various cancers. However, the biological function and prognostic value of TRPVs in
Yuxiong Jiang +8 more
doaj +1 more source
The membrane-associated transient receptor potential vanilloid channel is the central heat shock receptor controlling the cellular heat shock response in epithelial cells. [PDF]
PLoS ONE, 2013 The heat shock response (HSR) is a highly conserved molecular response to various types of stresses, including heat shock, during which heat-shock proteins (Hsps) are produced to prevent and repair damages in labile proteins and membranes.
Zohar Bromberg +3 more
doaj +1 more source
A functional nuclear localization sequence in the C. elegans TRPV channel OCR-2. [PDF]
PLoS ONE, 2011 The ability to modulate gene expression in response to sensory experience is critical to the normal development and function of the nervous system. Calcium is a key activator of the signal transduction cascades that mediate the process of translating a ...
Meredith J Ezak, Denise M Ferkey
doaj +1 more source