Stimulation of TRPV1 by green laser light [PDF]
Low-level laser irradiation of visible light had been introduced as a medical treatment already more than 40 years ago, but its medical application still remains controversial.
Gu, Quanbao +3 more
core +2 more sources
Functional expression of TRPV4 channels in human collecting duct cells: implications for secondary hypertension in diabetic nephropathy [PDF]
Background. The Vanilloid subfamily of transient receptor potential (TRPV) ion channels has been widely implicated in detecting osmotic and mechanical stress.
Bland, Rosemary +2 more
core +3 more sources
The Basal Thermal Sensitivity of the TRPV1 Ion Channel Is Determined by PKCβII [PDF]
Copyright © 2014 the authors 0270-6474/14/348246-13$15.00/0.Peer reviewedPublisher ...
Hasan, Raquibul, Li, Lin, Zhang, Xuming
core +1 more source
BackgroundThe transient receptor potential vanilloid (TRPV) channels family, TRPV1-6, has been identified to profoundly affect a wide spectrum of pathological processes in various cancers. However, the biological function and prognostic value of TRPVs in
Yuxiong Jiang +8 more
doaj +1 more source
Structural insights on TRPV5 gating by endogenous modulators. [PDF]
TRPV5 is a transient receptor potential channel involved in calcium reabsorption. Here we investigate the interaction of two endogenous modulators with TRPV5.
Carnevale, Vincenzo +13 more
core +3 more sources
Heat Activation of TRPV Channels [PDF]
Activation of TRPV1-4 channels is exquisitely heat-sensitive due to large and balanced changes in entropy and enthalpy. Identification of channel structures that underlie these changes is thus the prerequisite for understanding the molecular mechanism of heat activation. We approach this goal through a combination of methods.
openaire +1 more source
The membrane-associated transient receptor potential vanilloid channel is the central heat shock receptor controlling the cellular heat shock response in epithelial cells. [PDF]
The heat shock response (HSR) is a highly conserved molecular response to various types of stresses, including heat shock, during which heat-shock proteins (Hsps) are produced to prevent and repair damages in labile proteins and membranes.
Zohar Bromberg +3 more
doaj +1 more source
A functional nuclear localization sequence in the C. elegans TRPV channel OCR-2. [PDF]
The ability to modulate gene expression in response to sensory experience is critical to the normal development and function of the nervous system. Calcium is a key activator of the signal transduction cascades that mediate the process of translating a ...
Meredith J Ezak, Denise M Ferkey
doaj +1 more source
Top-Quark Phenomenology in Models with Bilinearly and Spontaneously Broken R-parity [PDF]
We study unconventional decays of the top-quark in the framework of SUSY models with spontaneously broken R-parity. In particular we discuss an effective theory which consists of the MSSM plus bilinearly broken R-parity.
Akeroyd +10 more
core +3 more sources
Selective disruption of high sensitivity heat activation but not capsaicin activation of TRPV1 channels by pore turret mutations. [PDF]
The capsaicin receptor transient receptor potential vanilloid (TRPV)1 is a highly heat-sensitive ion channel. Although chemical activation and heat activation of TRPV1 elicit similar pungent, painful sensation, the molecular mechanism underlying ...
Cao, Xu +5 more
core +1 more source

