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Trypanocidal Essential Oils: A Review
Trypanosomiases are diseases caused by parasitic protozoan trypanosomes of the genus Trypanosoma. In humans, this includes Chagas disease and African trypanosomiasis. There are few therapeutic options, and there is low efficacy to clinical treatment. Therefore, the search for new drugs for the trypanosomiasis is urgent. This review describes studies of
Mayara Castro de Morais +4 more
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Background Parasite persistence, exacerbated and sustained immune response, and continuous oxidative stress have been described to contribute to the development of the cardiac manifestations in Chronic Chagas Disease. Nevertheless, there are no efficient
Wendy Lorena Quintero +5 more
doaj +1 more source
Action trypanocide de deux sels d'isométamidium
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Pierre Finelle, R. Lacotte
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The Trypanocidal Activity of Naphthoquinones: A Review [PDF]
Naphthoquinones are compounds present in several families of higher plants. Their molecular structures confer redox properties, and they are involved in multiple biological oxidative processes. In folk medicine, especially among Indian populations, plants containing naphthoquinones have been employed for the treatment of various diseases.
Pinto, Antônio Ventura +1 more
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Background Human African trypanosomiasis (HAT) is a neglected tropical disease caused by Trypanosoma brucei gambiense transmitted by tsetse flies in sub-Saharan West Africa. In southern Chad the most active and persistent focus is the Mandoul focus, with
Mahamat Hissene Mahamat +8 more
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Dans une région bien délimitée du Nord de la Côte-d'Ivoire où la trypanosomose provoque une importante mortalité chez les très jeunes veaux taurins essentiellement de race Baoulé, pourtant réputée pour la qualité de sa trypanotolérance - une unique ...
Emmanuel Camus
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Clinical trials for Chagas disease: etiological and pathophysiological treatment
Chagas disease (CD) is caused by the flagellate protozoan Trypanosoma cruzi. It is endemic in Latin America. Nowadays around 6 million people are affected worldwide, and 75 million are still at risk. CD has two evolutive phases, acute and chronic.
Beatriz Matheus de Souza Gonzaga +5 more
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Trypanosoma brucei relies on uptake and conversion of purines from the host, which constitutes a potential drug target. Here, Hulpia et al. combine structural elements from known trypanocidal nucleoside analogues and develop a potent trypanocide with ...
Fabian Hulpia +9 more
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L'autrycide et l'avenir de l'élevage africain
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Georges Curasson
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African animal trypanosomosis (AAT) in cattle is primarily managed through trypanocide administration and insecticide application. Trypanocides can be used for both treatment and prophylaxis, but failure is often reported; this may occur due to ...
Shauna Richards +13 more
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