Results 31 to 40 of about 1,895 (212)

Résistance médicamenteuse d'isolats récents de Trypanosoma brucei et Trypanosoma congolense

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1988
Des études ont été menées sur des souris pour déterminer la sensibilité aux médicaments d’isolats récents de Trypanosoma brucei et Trypanosoma congolense. Chacune des onze souches de T. congolense et des cinq souches de T. brucei, toutes isolées sur des
R.A. Joshua
doaj   +1 more source

Essai de l’efficacité du Cymelarsan™ sur Trypanosoma evansi chez le dromadaire

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1989
L’expérimentation au Niger d’une nouvelle molécule arsenicale, susceptible d’être utilisée dans le traitement de la trypanosomose cameline à Trypanosoma evansi a démontré, au cours d’un essai d’efficacité effectué sur 8 jeunes dromadaires infestés ...
Pierre Tager-Kagan   +2 more
doaj   +1 more source

Trypanocidal Activity of Flavanone Derivatives [PDF]

open access: yesMolecules, 2020
Chagas disease, also known as American trypanosomiasis, is classified as a neglected disease by the World Health Organization. For clinical treatment, only two drugs have been on the market, Benznidazole and Nifurtimox, both of which are recommended for use in the acute phase but present low cure rates in the chronic phase.
Gabriela Maciel Diogo   +5 more
openaire   +3 more sources

Sensibilité aux trypanocides et au plasma humain de souches de Trypanozoon isolées d’animaux provenant de foyers endémiques de maladie du sommeil au Nigeria

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1995
La sensibilité de douze souches de Trypanozoon isolées de bovins semi-nomades provenant de foyers endémiques connus de maladie du sommeil situés dans le Centre et au Nord du Nigeria a été étudiée vis-à-vis de deux trypanocides, l'acéturate de diminazène (
A.I. Kalu
doaj   +1 more source

Integrated cost-benefit analysis of tsetse control and herd productivity to inform control programs for animal African trypanosomiasis [PDF]

open access: yes, 2018
Animal African trypanosomiasis (AAT) and its tsetse vector are responsible for annual losses estimated in billions of US dollars ($). Recent years have seen the implementation of a series of multinational interventions.
Chilongo, K   +7 more
core   +1 more source

Anti-Trypanosoma cruzi action of a new benzofuran derivative based on amiodarone structure [PDF]

open access: yes, 2018
Chagas disease is a neglected tropical affection caused by the protozoan parasite Trypanosoma cruzi. There is no current effective treatment since the only two available drugs have a limited efficacy and produce side effects.
Benaim, Gustavo   +4 more
core   +1 more source

Integrated control of chagas disease for its elimination as public health problem: A review [PDF]

open access: yes, 2015
Chagas disease or American trypanosomiasis is, together with geohelminths, the neglected disease that causes more loss of years of healthy life due to disability in Latin America.
Segura, Elsa Leonor   +1 more
core   +4 more sources

Immunomodulatory, trypanocide, and antioxidant properties of essential oil fractions of Lippia alba (Verbenaceae)

open access: yesBMC Complementary Medicine and Therapies, 2021
Background Parasite persistence, exacerbated and sustained immune response, and continuous oxidative stress have been described to contribute to the development of the cardiac manifestations in Chronic Chagas Disease. Nevertheless, there are no efficient
Wendy Lorena Quintero   +5 more
doaj   +1 more source

Independence from kinetoplast DNA maintenance and expression is associated with multi-drug resistance in Trypanosoma brucei in vitro [PDF]

open access: yes, 2014
It is well known that several antitrypanosomatid drugs accumulate in the parasite's mitochondrion, where they often bind to the organellar DNA, the kinetoplast.
A. Schnaufer   +32 more
core   +1 more source

Combining tubercidin and cordycepin scaffolds results in highly active candidates to treat late-stage sleeping sickness

open access: yesNature Communications, 2019
Trypanosoma brucei relies on uptake and conversion of purines from the host, which constitutes a potential drug target. Here, Hulpia et al. combine structural elements from known trypanocidal nucleoside analogues and develop a potent trypanocide with ...
Fabian Hulpia   +9 more
doaj   +1 more source

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