Results 31 to 40 of about 640 (163)

The Trypanocidal Activity of Naphthoquinones: A Review [PDF]

Molecules, 2009
Naphthoquinones are compounds present in several families of higher plants. Their molecular structures confer redox properties, and they are involved in multiple biological oxidative processes. In folk medicine, especially among Indian populations, plants containing naphthoquinones have been employed for the treatment of various diseases.
Pinto, Antônio Ventura, Castro, Solange Lisboa de   +1 more
openaire   +3 more sources

Note sur un essai de traitement trypanocide pour lutter contre la primo-infection chez les veaux Baoulé

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1980
Dans une région bien délimitée du Nord de la Côte-d'Ivoire où la trypanosomose provoque une importante mortalité chez les très jeunes veaux taurins essentiellement de race Baoulé, pourtant réputée pour la qualité de sa trypanotolérance - une unique ...
Emmanuel Camus
doaj   +1 more source

Trypanocidal Effects of Curcumin in Vitro.

Biological and Pharmaceutical Bulletin, 1998
During the course of study searching for the antiparasitic agents from natural compounds, we found that curcumin showed cytotoxicity against African trypanosomes in vitro. The LD50 values of curcumin were 4.77 +/- 0.91 microM for bloodstream forms and 46.52 +/- 4.94 microM for procyclic forms of Trypanosoma brucei brucei (GUTat 3.1 clone).
NOSE, Mitsuhiko, KOIDE, Tatsuo, OGIHARA, Yukio, YABU, Yoshisada, OHTA, Nobuo   +4 more
openaire   +2 more sources

Combining tubercidin and cordycepin scaffolds results in highly active candidates to treat late-stage sleeping sickness

Nature Communications, 2019
Trypanosoma brucei relies on uptake and conversion of purines from the host, which constitutes a potential drug target. Here, Hulpia et al. combine structural elements from known trypanocidal nucleoside analogues and develop a potent trypanocide with ...
Fabian Hulpia, Dorien Mabille, Gustavo D. Campagnaro, Gabriela Schumann, Louis Maes, Isabel Roditi, Anders Hofer, Harry P. de Koning, Guy Caljon, Serge Van Calenbergh   +9 more
doaj   +1 more source

L'autrycide et l'avenir de l'élevage africain

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1950
Aucun résumé disponible.
Georges Curasson
doaj   +1 more source

The efficacy of furazolidone against experimental infections with Trypanosoma evansi in camels and mice in Sudan : comparisons with quinapyramine and suramin

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1986
L'efficacité du furazolidone contre les infections expérimentales à Trypanosoma evansi a été étudiée chez les dromadaires et les souris. Les critères de mise en évidence de l'effet trypanocide du furazolidone comprenaient la recherche de T.
B.H. Ali, T. Hassan, K.H. Malik
doaj   +1 more source

Antitrypanosomal Activity and Molecular Docking Studies of Lobetyolin From Lobelia rhynchopetalum Hemsl. Root Extract Against Trypanosoma congolense Field Isolates

BioMed Research International, Volume 2026, Issue 1, 2026.
Currently available drugs for trypanosomiasis are few, and their use is limited by toxicity and growing resistance. This highlights the need for safer and more effective alternatives. In this study, the in vitro and in vivo antitrypanosomal activities of an 80% methanol root extract of Lobelia rhynchopetalum and its major constituent were evaluated ...
Selamawit Yimer, Eyael Tewelde, Daniel Bisrat, Solomon Tadesse, Mariamawit Y. Yeshak, Rahul Shivahare   +5 more
wiley   +1 more source

Prevalence of Unregistered, Substandard, and Falsified Veterinary Antimicrobials in Ethiopia: A National Postmarket Quality Surveillance Study

Veterinary Medicine International, Volume 2026, Issue 1, 2026.
Background The proliferation of unregistered, substandard, and falsified (SF) veterinary pharmaceuticals represents a critical global threat to animal health, food security, and environmental conservation. In sub‐Saharan Africa, these products exacerbate the emergence of antimicrobial resistance (AMR), potentially accelerating the transition toward a ...
Belachew Tefera, Belachew Bacha, Nardos Tefera, Gudeta Uma, Tadese Setegn, Bizuayehu Belete, Diriba Daba, Dinsefa Jemal, Yilak Tefera, Hussen Bedu, Tamiru Tilki, Dagnachew Hailemichael, Solomon Kebede, Hamid Jemal, Tesfa Marew, Dawit Teshome, Teferi Gedif, Esayas Gelaye, Tenaw Andualem, Ayenew Ashenef, Lipi Buch   +20 more
wiley   +1 more source

L'influence de quelques corps chimiques sur la survie in vitro de Trypanosoma evansi. I. Acides aminés et quelques-uns de leurs dérivés

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1965
L'auteur a étudié le comportement, in vitro, de T. evansi en présence de 23 acides aminés et de 13 de leurs dérivés. Le glutathion, la cysteine et les composés possédant un groupement S H dans leur molécule interviennent très activement dans les ...
J. Balis
doaj   +1 more source

Synthesis of (-) - 6,6'-dinitrohinokinin from hinokinin natural product and in silico and in vitro trypanocidal activity assessment

Bioscience Journal
Chagas disease is a public health problem affecting approximately seven million people worldwide. Thus, there is a need to discover drugs for the adequate treatment of this disease because currently available drugs have serious side effects.
Suziene Caroline Silva Cardoso, Wilson R. Cunha, Pedro S. dos S. R. Cavallari, Samarah Gomes de Almeida, Ana Helena Januário, Patrícia Mendonça Pauletti, Fernanda Amorim Santos, Rosângela da Silva Laurentiz, Giulia Stavrakas Miranda, João Victor Andrade, Renato Pereira Orenha, Renato Luis Tame Parreira, Márcio Luís Andrade e Silva, Mario F. C. Santos, Viviane Esperandim   +14 more
doaj   +1 more source