Results 51 to 60 of about 192 (126)
Insect Science, Volume 32, Issue 5, Page 1713-1725, October 2025.Abstract Sterile Insect Technique (SIT) has proven effective to reduce tsetse population density in large infected areas where animal African trypanosomosis (AAT) and human African trypanosomiasis (HAT) elimination was difficult to achieve. However, the decrease in mass production of insectary‐reared tsetse and the limited but incomplete knowledge on ...
Steve Feudjio Soffack +12 more
wiley +1 more source
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1990 La cinétique des anticorps anti-trypanosomes a été étudiée en immunofluorescen ce indirecte (IFI) et en ELISA chez des bovins infectés expérimentalement par Trypanosoma congolense ou naturellement dans une zone à forte pression glossinaire.
R. Bocquentin, P. Very, Gérard Duvallet
doaj +1 more source
Immune Response in Cattle Trypanosomosis and Trypanotolerance: Main Findings and Gaps
Parasite Immunology, Volume 46, Issue 11, November 2024.ABSTRACT Trypanosome parasites of the genus Trypanosoma cause African animal trypanosomosis, a devastating livestock disease plaguing sub‐Saharan Africa. Unlike many protozoan parasites, these extracellular blood‐borne pathogens directly engage the host's immune system. While the mouse model has provided valuable insights, a comprehensive understanding
Gnohion Fabrice Somé +9 more
wiley +1 more source
Infection expérimentale de zébus guyanais avec Trypanosoma vivax
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1990 La souche guyanaise de Trypanosoma vivax est pathogène pour le zébu guyanais de type Brahman : l'infection expérimentale de 19 bovins, agés d'un an, s'est traduite par de la fièvre (peu élevée et transitoire), une chute de l'hématocrite et une perte de ...
Emmanuel Camus, Arnaud Martrenchar
doaj +1 more source
ChemMedChem, Volume 19, Issue 9, May 2, 2024.Several (sub)species of Trypanosoma are responsible for human African trypanosomiasis (HAT), Chagas disease, and Nagana. These (sub)species have different drug susceptibility profiles. This work reports several easily accessed quinolone hydrazides exhibiting sub‐micromolar activities against multiple (sub)species of Trypanosoma.
Kgothatso A. Chirwa +7 more
wiley +1 more source
DFMO inhibition of neuroblastoma tumorigenesis
Cancer Medicine, Volume 13, Issue 9, May 2024.Abstract Background Most high‐risk neuroblastoma patients who relapse succumb to disease despite the existing therapy. We recently reported increased event‐free and overall survival in neuroblastoma patients receiving difluoromethylornithine (DFMO) during maintenance therapy.
Divya Gandra +8 more
wiley +1 more source
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1991 Les auteurs ont étudié l'activité théapeutique et prophylactique de l'association DL-alpha-difluorométhylornithine (à la dose de 2 % dans l'eau de boisson) et BerenilR (à 7 mg par kg de poids vif par voie intrapéritonéale) sur des souris infectées par ...
P.A. Onyeyili +3 more
doaj +1 more source
Fundamental &Clinical Pharmacology, Volume 38, Issue 1, Page 72-83, February 2024.Abstract Human African trypanosomosis (HAT) which is also known as sleeping sickness is caused by Trypanosoma brucei gambiense that is endemic in western and central Africa and T. b. rhodesiense that is endemic in eastern and southern Africa. Drugs used for treatment against HAT first stage have limited effectiveness, and the second stage drugs have ...
Anna Seetsi +5 more
wiley +1 more source
The script supports Chapter 5 subsection 2 titled: “Trypanocide advancements and challenges in Uganda” from my PhD thesis titled: Exploring trypanocide resistance: Lessons from Uganda (2024). This describes data (referenced as “trypCounterfeit”) were the quality of trypanocides i.e., diminazene aceturate (DA), isometamidium chloride (ISM) and homidium ...
Kasozi, Keneth Iceland +2 more
openaire +2 more sources
Biogenic trypanocidal sesquiterpenes: lead compounds to design future trypanocidal drugs - a mini review [PDF]
DARU Journal of Pharmaceutical Sciences, 2013 Abstract Human trypanosomiasis is a parasitic disease among poor people in Africa and Latin America. Therapy against African and American trypanosomiasis is based on a few drugs that often cause severe side-effects. Therefore, it is essential to develop drug discovery especially from natural origins. Sesquiterpenes, a diverse group of natural
Saeidnia, Soodabeh +2 more
openaire +2 more sources