Results 51 to 60 of about 944 (184)

Traitement de la maladie du sommeil du bétail au dimidium bromide

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1948
Aucun résumé disponible.
M. Blommaert
doaj   +1 more source

Synthesis and Evaluation of Trypanocidal Activity of Chromane-Type Compounds and Acetophenones

Molecules, 2021
American trypanosomiasis (Chagas disease) caused by the Trypanosoma cruzi parasite, is a severe health problem in different regions of Latin America and is currently reported to be spreading to Europe, North America, Japan, and Australia, due to the ...
Luis A. González, Sara Robledo, Yulieth Upegui, Gustavo Escobar, Wiston Quiñones   +4 more
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Natural Products from Mexican Medicinal Plants as Promising Trypanocidal Drugs

ChemistrySelect, Volume 10, Issue 37, October 6, 2025.
Chagas disease (American Trypanosomiasis) is caused by the protozoan Trypanosoma cruzi. Worldwide it is one of the seventeen neglected tropical diseases. There is a need of new drugs. This review assesses the literature (2012‐2024) of secondary metabolites isolated from Mexican plants active against this parasite.
Karla Daniela Rodríguez‐Hernández, Elia Guadalupe Jaimes‐Castelán, Ricardo Reyes‐Chilpa   +2 more
wiley   +1 more source

Potent Antitrypanosomal Activities of 3-Aminosteroids against African Trypanosomes: Investigation of Cellular Effects and of Cross-Resistance with Existing Drugs

Molecules, 2019
Treatment of animal African trypanosomiasis (AAT) requires urgent need for safe, potent and affordable drugs and this has necessitated this study.
Charles O. Nnadi, Godwin U. Ebiloma, Jennifer A. Black, Ngozi J. Nwodo, Leandro Lemgruber, Thomas J. Schmidt, Harry P. de Koning   +6 more
doaj   +1 more source

Impact of long‐term mass‐rearing on the genetic structure of tsetse fly Glossina palpalis gambiensis colonies

Insect Science, Volume 32, Issue 5, Page 1575-1587, October 2025.
Abstract Tsetse flies are the sole cyclic vectors of African trypanosomes, which cause human and animal African trypanosomiases in Africa. Tsetse fly control remains a promising option for disease management. The sterile insect technique (SIT) stands as an environmentally friendly tool to control tsetse populations.
Kiswend‐sida M. Dera, Soumaïla Pagabeleguem, Tito Tresor Melachio Tanekou, Ange Irénée Toé, Gisèle Marie Sophie Ouedraogo‐Sanou, Adrien Marie Gaston Belem, Sophie Ravel, Robert L. Mach, Marc J. B. Vreysen, Adly M.M. Abd‐Alla   +9 more
wiley   +1 more source

Evaluation of two candidate molecules—TCTP and cecropin—on the establishment of Trypanosoma brucei gambiense into the gut of Glossina palpalis gambiensis

Insect Science, Volume 32, Issue 5, Page 1747-1760, October 2025.
This study investigates the potential of enhancing the resistance of Glossina palpalis gambiensis to Trypanosoma brucei gambiense to mitigate the transmission of Human African Trypanosomiasis. We successfully cloned genes encoding proteins of interest in Sodalis strains, resulting in recombinant Sodalis (recSodalis) that were micro‐injected into the L3
François Sougal Ngambia Freitas, Linda De Vooght, Flobert Njiokou, Jan Van Den Abeele, Géraldine Bossard, Bernadette Tchicaya, Rosa Milagros Corrales, Sophie Ravel, Anne Geiger, David Berthier‐Teyssedre   +9 more
wiley   +1 more source

Spatiotemporal changes in prevalence of Sodalis glossinidius, Spiroplasma spp. and trypanosome species in wild Glossina tachinoides from Sora‐Mboum animal African trypanosomiasis focus in northern Cameroon

Insect Science, Volume 32, Issue 5, Page 1713-1725, October 2025.
Abstract Sterile Insect Technique (SIT) has proven effective to reduce tsetse population density in large infected areas where animal African trypanosomosis (AAT) and human African trypanosomiasis (HAT) elimination was difficult to achieve. However, the decrease in mass production of insectary‐reared tsetse and the limited but incomplete knowledge on ...
Steve Feudjio Soffack, Tito T. Melachio Tanekou, Hugues C. Nana Djeunga, Oumarou Farikou, Ginette I. Kame Ngasse, Mureille C. Tchami Mbagnia, Murielle Wondji, Charles S. Wondji, Hager Khalil, Adly M. M. Abd‐Alla, Anne Geiger, Gustave Simo, Flobert Njiokou   +12 more
wiley   +1 more source

Immune Response in Cattle Trypanosomosis and Trypanotolerance: Main Findings and Gaps

Parasite Immunology, Volume 46, Issue 11, November 2024.
ABSTRACT Trypanosome parasites of the genus Trypanosoma cause African animal trypanosomosis, a devastating livestock disease plaguing sub‐Saharan Africa. Unlike many protozoan parasites, these extracellular blood‐borne pathogens directly engage the host's immune system. While the mouse model has provided valuable insights, a comprehensive understanding
Gnohion Fabrice Somé, Modou Séré, Bienvenu Martin Somda, Guiguigbaza‐Kossigan Dayo, Georges Anicet Ouédraogo, Alain Boulangé, Ghizlane Maarifi, Isabelle Chantal, David Berthier‐Teyssedre, Sophie Thévenon   +9 more
wiley   +1 more source

Note sur la toxicité de l'Isométamidium par injection intraveineuse chez quelques mammifères domestiques et spécialement chez le dromadaire

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1977
Le chlorhydrate de chlorure d'Isométamidium est très mal supporté par le dromadaire à des doses supérieures à 1 mg/kg administrées par la voie ...
J. Balis
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Tractable Quinolone Hydrazides Exhibiting Sub‐Micromolar and Broad Spectrum Antitrypanosomal Activities

ChemMedChem, Volume 19, Issue 9, May 2, 2024.
Several (sub)species of Trypanosoma are responsible for human African trypanosomiasis (HAT), Chagas disease, and Nagana. These (sub)species have different drug susceptibility profiles. This work reports several easily accessed quinolone hydrazides exhibiting sub‐micromolar activities against multiple (sub)species of Trypanosoma.
Kgothatso A. Chirwa, Karol R. Francisco, Phelelisiwe S. Dube, Hayoung Park, Lesetja J. Legoabe, Thaiz Rodrigues Teixeira, Conor R. Caffrey, Richard M. Beteck   +7 more
wiley   +1 more source