Results 61 to 70 of about 640 (163)

In vitro anti‐trypanosomal activity of synthetic nitrofurantoin‐triazole hybrids against Trypanosoma species causing human African trypanosomosis

Fundamental &Clinical Pharmacology, Volume 38, Issue 1, Page 72-83, February 2024.
Abstract Human African trypanosomosis (HAT) which is also known as sleeping sickness is caused by Trypanosoma brucei gambiense that is endemic in western and central Africa and T. b. rhodesiense that is endemic in eastern and southern Africa. Drugs used for treatment against HAT first stage have limited effectiveness, and the second stage drugs have ...
Anna Seetsi, David D. N'da, Nthatisi Molefe‐Nyembe, Keisuke Suganuma, Tsepo Ramatla, Oriel Thekisoe   +5 more
wiley   +1 more source

The individual components of commercial isometamidium do not possess stronger trypanocidal activity than the mixture, nor bypass isometamidium resistance

International Journal for Parasitology: Drugs and Drug Resistance, 2019
The four components present in the trypanocidal treatment Samorin, the commercially available formulation of isometamidium, were separated and purified by column chromatography.
Anthonius A. Eze, John Igoli, Alexander I. Gray, Graham G. Skellern, Harry P. De Koning   +4 more
doaj   +1 more source

Evaluating 5-Nitrothiazoles as Trypanocidal Agents [PDF]

Antimicrobial Agents and Chemotherapy, 2016
ABSTRACTThe growth-inhibitory properties of a 5-nitrothiazole series were evaluated againstTrypanosoma brucei. A subset of related compounds displayed the greatest potency toward the parasite while exhibiting little cytotoxic effect on mammalian cells, with this antiparasitic activity dependent on expression of a type I nitroreductase by the ...
O'Shea, IP, Shahed, M, Aguilera-Venegas, B, WILKINSON, SR   +3 more
openaire   +3 more sources

Action trypanopréventive du M et B 4596

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1963
cf. fichier PDF de l'article.
Pierre Finelle, R. Lacotte
doaj   +1 more source

Detection of multiple drug-resistant Trypanosoma congolense populations in village cattle of south-east Mali

Parasites & Vectors, 2012
Background Tsetse fly-transmitted African animal trypanosomosis causes annual losses that run into billions of dollars. The disease is assumed to cause hunger and poverty in most sub-Saharan countries since it represents a serious impediment to ...
Mungube Erick O, Vitouley Hervé S, Allegye-Cudjoe Emmanuel, Diall Oumar, Boucoum Zakaria, Diarra Boucader, Sanogo Yousouf, Randolph Thomas, Bauer Burkhard, Zessin Karl-Hans, Clausen Peter-Henning   +10 more
doaj   +1 more source

Recherches sur la toxicité et la valeur trypanopréventive du moranylate d'éthidium. I

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1961
cf. fichier PDF de l'article.
R. Sauvel, M. Thomé
doaj   +1 more source

Cost analysis of options for management of African Animal Trypanosomiasis using interventions targeted at cattle in Tororo District; south-eastern Uganda

Parasites & Vectors, 2015
Background Tsetse-transmitted African trypanosomes cause both nagana (African animal Trypanosomiasis-AAT) and sleeping sickness (human African Trypanosomiasis - HAT) across Sub-Saharan Africa.
Dennis Muhanguzi, Walter O. Okello, John D. Kabasa, Charles Waiswa, Susan C. Welburn, Alexandra P.M. Shaw   +5 more
doaj   +1 more source

Incidence de la trypanosomose bovine au ranch de Madina-Diassa (Mali). Traitement curatif des animaux malades

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1986
L'objectif principal de cette étude était de définir une stratégie de lutte contre la trypanosomose chez les N'Dama dans les conditions du ranch de Madina-Diassa.
O. Diall, Z. Bocoum, Y. Sanogo, Z. Yattara   +3 more
doaj   +1 more source

Action trypanocide du chlorhydrate de chlorure d'Isométamidium (+) sur Trypanosoma evansi et essai de traitement de la trypanosomiase du dromadaire

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1977
Le chlorhydrate de chlorure d'Isométamidium est doué de peu d'activité à l'égard de Trypanosoma evansi. En l'absence de produits plus actifs, son utilisation chez le dromadaire par injection intraveineuse ou intramusculaire à des doses comprises entre 0 ...
J. Balis, Didier Richard
doaj   +1 more source

Trypanosomose et traitements trypanocides chez le veau Ndama en milieu fortement infesté de glossines (ranch de Madina-Diassa au Mali)

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1992
L'épidémiologie de la trypanosomose chez les veaux de race trypanotolérante et l'influence d'un traitement font l'objet de deux études. La première consiste en un suivi parasitologique et clinique de 100 veaux, de la naissance à l'âge d'un an : les ...
O. Diall, O.B. Touré, B. Diarra, Y. Sanogo   +3 more
doaj   +1 more source