Results 61 to 70 of about 1,895 (212)

Spatiotemporal changes in prevalence of Sodalis glossinidius, Spiroplasma spp. and trypanosome species in wild Glossina tachinoides from Sora‐Mboum animal African trypanosomiasis focus in northern Cameroon

Insect Science, Volume 32, Issue 5, Page 1713-1725, October 2025.
Abstract Sterile Insect Technique (SIT) has proven effective to reduce tsetse population density in large infected areas where animal African trypanosomosis (AAT) and human African trypanosomiasis (HAT) elimination was difficult to achieve. However, the decrease in mass production of insectary‐reared tsetse and the limited but incomplete knowledge on ...
Steve Feudjio Soffack, Tito T. Melachio Tanekou, Hugues C. Nana Djeunga, Oumarou Farikou, Ginette I. Kame Ngasse, Mureille C. Tchami Mbagnia, Murielle Wondji, Charles S. Wondji, Hager Khalil, Adly M. M. Abd‐Alla, Anne Geiger, Gustave Simo, Flobert Njiokou   +12 more
wiley   +1 more source

Immune Response in Cattle Trypanosomosis and Trypanotolerance: Main Findings and Gaps

Parasite Immunology, Volume 46, Issue 11, November 2024.
ABSTRACT Trypanosome parasites of the genus Trypanosoma cause African animal trypanosomosis, a devastating livestock disease plaguing sub‐Saharan Africa. Unlike many protozoan parasites, these extracellular blood‐borne pathogens directly engage the host's immune system. While the mouse model has provided valuable insights, a comprehensive understanding
Gnohion Fabrice Somé, Modou Séré, Bienvenu Martin Somda, Guiguigbaza‐Kossigan Dayo, Georges Anicet Ouédraogo, Alain Boulangé, Ghizlane Maarifi, Isabelle Chantal, David Berthier‐Teyssedre, Sophie Thévenon   +9 more
wiley   +1 more source

Cytotoxicity and trypanocidal activity of nifurtimox encapsulated in ethylcyanoacrylate nanoparticles

Biological Research, 2002
The aim of the present study was to study the trypanocidal activity of nanoparticles loaded with nifurtimox in comparison with the free drug against Trypanosoma cruzi, responsible for Chagas' disease.
GITTITH SÁNCHEZ, DANIELA CUELLAR, INES ZULANTAY, MARTA GAJARDO, GUILLERMO GONZÁLEZ-MARTIN   +4 more
doaj  

Note sur la toxicité de l'Isométamidium par injection intraveineuse chez quelques mammifères domestiques et spécialement chez le dromadaire

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1977
Le chlorhydrate de chlorure d'Isométamidium est très mal supporté par le dromadaire à des doses supérieures à 1 mg/kg administrées par la voie ...
J. Balis
doaj   +1 more source

Best-bet integrated strategies for containing drug-resistant trypanosomes in cattle [PDF]

, 2012
Background African animal trypanosomosis is a major constraint to the rearing of productive livestock in the sub-humid Sudan-Sahel zone of West Africa where cotton is grown.
Bauer, Burkhard, Baumann, Maximilian P. O., Diall, Oumar, Hinney, Barbara, Hoppenheit, Antje, Maiga, Brehima, Mungube, Erick O., Randolph, Thomas F., Sanogo, Yousouf, Zessin, Karl-Hans   +9 more
core   +1 more source

Tractable Quinolone Hydrazides Exhibiting Sub‐Micromolar and Broad Spectrum Antitrypanosomal Activities

ChemMedChem, Volume 19, Issue 9, May 2, 2024.
Several (sub)species of Trypanosoma are responsible for human African trypanosomiasis (HAT), Chagas disease, and Nagana. These (sub)species have different drug susceptibility profiles. This work reports several easily accessed quinolone hydrazides exhibiting sub‐micromolar activities against multiple (sub)species of Trypanosoma.
Kgothatso A. Chirwa, Karol R. Francisco, Phelelisiwe S. Dube, Hayoung Park, Lesetja J. Legoabe, Thaiz Rodrigues Teixeira, Conor R. Caffrey, Richard M. Beteck   +7 more
wiley   +1 more source

Past and Ongoing Tsetse and Animal Trypanosomiasis Control Operations in Five African Countries: A Systematic Review [PDF]

, 2016
Background Control operations targeting Animal African Trypanosomiasis and its primary vector, the tsetse, were covering approximately 128,000 km2 of Africa in 2001, which is a mere 1.3% of the tsetse infested area.
Guitian, J, Holt, H R, Meyer, A, Selby, R   +3 more
core   +11 more sources

African Trypanosomes undermine humoral responses and vaccine development : link with inflammatory responses? [PDF]

, 2017
African trypanosomosis is a debilitating disease of great medical and socioeconomical importance. It is caused by strictly extracellular protozoan parasites capable of infecting all vertebrate classes including human, livestock, and game animals.
Achcar, Alampour-Rajabi, Alirol, Allman, Authie, Authié, Auty, Baker, Balber, Banks, Barry, Barry, Berthier, Beschin, Beschin, Blom-Potar, Bockstal, Bockstal, Boller, Bonnet, Borst, Bosschaerts, Boulange, Bouyer, Brun, Brun, Bucheton, Calandra, Capewell, Chamond, Claes, Cnops, Cnops, Cnops, Cnops, Coller, Dagenais, Darji, De Muylder, De Trez, Delafosse, Delespaux, Desquesnes, Devine, Disease, Drennan, Dubois, Duszenko, Engstler, Fenn, Ferrante, Field, Figarella, Franco, Frenkel, Gilbert, Giordani, Gomez-Rodriguez, Graham, Graham, Haanstra, Hall, Hasker, Hemphill, Holland, Holland, Holt, Jamonneau, Jarvinen, Jones, Keitany, Kennedy, Kennedy, Klasen, Kondo, Kroubi, Kuriakose, La Greca, La Greca, Lalmanach, Lanca, Lebien, Lejon, Lejon, Leng, MacGregor, MacGregor, MacLean, MacLean, Magez, Magez, Magez, Mansfield, McGettrick, Mekori, Millar, Mogk, Mony, Morrison, Morrison, Morrison, Mulindwa, Mårtensson, Naessens, Naula, Ng, Nutt, Obishakin, Odongo, Onyilagha, Ooi, Ooi, Osório, O’Gorman, Paulnock, Pays, Peacock, Priotto, Radwanska, Radwanska, Reth, Rico, Rodgers, Rotureau, Ruiz-Postigo, Salmon, Schwede, Schwede, Seed, Sharpe, Sileghem, Sileghem, Simarro, Simarro, Simarro, Stijlemans, Stijlemans, Stijlemans, Stijlemans, Stijlemans, Stijlemans, Stijlemans, Swallow, Takeya, Taylor, Taylor, Taylor, Telleria, Tiberti, Trindade, Unciti-Broceta, Uzonna, Uzonna, Van Den Abbeele, Vassella, Welburn, Welburn, Wellde, Wenzler, Willert, Yaro   +160 more
core   +1 more source

Trypanocide counterfeits

The script supports Chapter 5 subsection 2 titled: “Trypanocide advancements and challenges in Uganda” from my PhD thesis titled: Exploring trypanocide resistance: Lessons from Uganda (2024). This describes data (referenced as “trypCounterfeit”) were the quality of trypanocides i.e., diminazene aceturate (DA), isometamidium chloride (ISM) and homidium ...
Kasozi, Keneth Iceland, MacLeod, Ewan Thomas, Welburn, Susan Christina   +2 more
openaire   +2 more sources

Evaluating 5-Nitrothiazoles as Trypanocidal Agents [PDF]

Antimicrobial Agents and Chemotherapy, 2016
ABSTRACTThe growth-inhibitory properties of a 5-nitrothiazole series were evaluated againstTrypanosoma brucei. A subset of related compounds displayed the greatest potency toward the parasite while exhibiting little cytotoxic effect on mammalian cells, with this antiparasitic activity dependent on expression of a type I nitroreductase by the ...
O'Shea, IP, Shahed, M, Aguilera-Venegas, B, WILKINSON, SR   +3 more
openaire   +3 more sources