Results 71 to 80 of about 1,895 (212)
DFMO inhibition of neuroblastoma tumorigenesis
Cancer Medicine, Volume 13, Issue 9, May 2024.Abstract Background Most high‐risk neuroblastoma patients who relapse succumb to disease despite the existing therapy. We recently reported increased event‐free and overall survival in neuroblastoma patients receiving difluoromethylornithine (DFMO) during maintenance therapy.
Divya Gandra +8 more
wiley +1 more source
Fundamental &Clinical Pharmacology, Volume 38, Issue 1, Page 72-83, February 2024.Abstract Human African trypanosomosis (HAT) which is also known as sleeping sickness is caused by Trypanosoma brucei gambiense that is endemic in western and central Africa and T. b. rhodesiense that is endemic in eastern and southern Africa. Drugs used for treatment against HAT first stage have limited effectiveness, and the second stage drugs have ...
Anna Seetsi +5 more
wiley +1 more source
Infection expérimentale de zébus guyanais avec Trypanosoma vivax
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1990 La souche guyanaise de Trypanosoma vivax est pathogène pour le zébu guyanais de type Brahman : l'infection expérimentale de 19 bovins, agés d'un an, s'est traduite par de la fièvre (peu élevée et transitoire), une chute de l'hématocrite et une perte de ...
Emmanuel Camus, Arnaud Martrenchar
doaj +1 more source
Evaluating 5-Nitrofurans as Trypanocidal Agents [PDF]
Antimicrobial Agents and Chemotherapy, 2013 ABSTRACTThe nitroheterocycle nifurtimox, as part of a nifurtimox-eflornithine combination therapy, represents one of a limited number of treatments targetingTrypanosoma brucei, the causative agent of human African trypanosomiasis. The mode of action of this prodrug involves an initial activation reaction catalyzed by a type I nitroreductase (NTR), an ...
Bot, C +6 more
openaire +3 more sources
, 2011 Melarsomine hydrochloride can cure Trypanosoma evansi infection in camels at a dose of 0·25 mg/kg, but at that dose relapses occur in cattle. In our study, the efficacy of an intramuscular injection of melarsomine hydrochloride at 0·5 mg/kg was assessed ...
Desquesnes, Marc +5 more
core +1 more source
Trypanocidal Activity of Marine Natural Products [PDF]
Marine Drugs, 2013 Marine natural products are a diverse, unique collection of compounds with immense therapeutic potential. This has resulted in these molecules being evaluated for a number of different disease indications including the neglected protozoan diseases, human African trypanosomiasis and Chagas disease, for which very few drugs are currently available.
Amy Jones +3 more
openaire +4 more sources
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1991 Les auteurs ont étudié l'activité théapeutique et prophylactique de l'association DL-alpha-difluorométhylornithine (à la dose de 2 % dans l'eau de boisson) et BerenilR (à 7 mg par kg de poids vif par voie intrapéritonéale) sur des souris infectées par ...
P.A. Onyeyili +3 more
doaj +1 more source
Enquête parasitologique et sérologique (Elisa-indirect) sur les trypanosomoses des bovins dans la zone de Sidéradougou, Burkina Faso [PDF]
, 1999 Une enquête parasitologique et sérologique sur les trypanosomoses des bovins a été réalisée dans le secteur nord de la zone de Sidéradougou (Burkina Faso), en novembre et décembre 1997.
Bengaly, Zakaria +6 more
core
International Journal for Parasitology: Drugs and Drug Resistance, 2019 The four components present in the trypanocidal treatment Samorin, the commercially available formulation of isometamidium, were separated and purified by column chromatography.
Anthonius A. Eze +4 more
doaj +1 more source
Effective communication to improve udder health: can social science help? [PDF]
, 2011 Improved udder health requires consistent application of appropriate management practices by those involved in managing dairy herds and the milking process. Designing effective communication requires that we understand why dairy herd managers behave in
Garforth, Chris
core +1 more source