Results 71 to 80 of about 640 (163)

Antiproliferative and Trypanocidal Activity of Ivermectin Bioconjugates [PDF]

ACS Omega
Ivermectin (IVR), whose discovery has been Nobel-Prize-honored, is a 16-membered macrocyclic lactone used in medicine as an extremely effective and safe antiparasitic drug. In recent years, interest in this compound has grown due to its potential effectiveness in killing various types of cancer cells. However, research on the anticancer activity of IVR
Michał Sulik, Dagmara Otto-Ślusarczyk, Dietmar Steverding, Marta Struga, Adam Huczyński   +4 more
openaire   +3 more sources

Culture in-vitro de Trypanosoma theileri sur des cellules thyroïdiennes bovines

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1982
Une souche de Trypanosoma theileri a été cultivée avec succès in vitro pendant cinq mois, respectivement à 37°C et à 23°C, sur des cellules thyroïdiennes de fotus bovin avec du milieu RPMI. 1640 additionné de 10 p. 100 (v/v) de sérum fotal bovin.
Vy Nguyen Ba Vy
doaj   +1 more source

Relations entre la fixation tissulaire et la durée d'action des trypanocides

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1962
cf. fichier PDF de l'article.
F. Bénazet
doaj   +1 more source

Recherches sur le moranylate de métamidium (9798 RP). 1. Note de présentation. 2. Toxicité. 3. Valeur trypanopréventive

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1961
cf. fichier PDF de l'article.
R. Sauvel, J. Balis, Pierre Finelle
doaj   +1 more source

Evaluación de la eficacia del tratamiento con aceturato de diminazeno en búfalos de agua infectados por Trypanosoma spp. en Colombia: ausencia de resistencia al fármaco

Infectio
Introduction: Hemotropic microorganisms, such as Trypanosoma spp., affect many animals, including water buffaloes. Some developing countries have reported trypanocide resistance to Diminazene Aceturate.
Ingrid Lorena Jaramillo-Delgado
doaj   +1 more source

Novel trypanocide from an extract of Pleurotus sajor-caju against Trypanosoma congolense

Pharmaceutical Biology, 2017
Context: Control of African trypanosomiasis relies on chemotherapy, but the development of resistance and the problem of drug residues require research for alternatives.
Isaiah O. Ademola, Paul O. Odeniran
doaj   +1 more source

Potential Trypanocidal Activity of Glycerol Analogues

ChemistryOpen
AbstractGlycerol, a versatile and ubiquitous compound, plays a vital role in a plethora of metabolic pathways in both prokaryotes and eukarotyes. Relatively few glycerol analogues have previously been explored for their use as glycerol kinase inhibitors, in addition to their therapeutic potential, however their use as (pro)‐drugs in the context of ...
R. A. Humann, T. K. Smith
openaire   +5 more sources

Trypanocidal efficacy of diminazene in diabetic rats [PDF]

Iraqi Journal of Veterinary Sciences, 2012
The experiment was conducted to investigate the impact of hyperglycaemia on the trypanocidal efficacy of diminazene aceturate. Groups of alloxan-induced diabetic rats infected with T. brucei and T.
U. S. Chigozie, A. B. Maduka, J. G. Ifeanyi   +2 more
doaj  

Trypanocidal effects of promethazine.

Medicina, 1998
Promethazine is currently used for its antipsychotic and ansiolytic effects. It is a phenothiazine with anticalmodulin action, not toxic for human beings at therapeutic doses. The present results show that promethazine has trypanocidal effect on both epimastigote and trypomastigote stages of T. cruzi; two hundred microM inhibited epimastigote growth in
A R, Fernández, R, Fretes, S, Rubiales, J L, Lacuara, P, Paglini-Oliva   +4 more
openaire   +1 more source

Does a One Health approach to human African trypanosomiasis control hasten elimination? A stochastic compartmental modeling approach. [PDF]

Acta Trop, 2023
Meisner J, Kato A, Lemerani MM, Miaka EM, Ismail AT, Wakefield J, Rowhani-Rahbar A, Pigott D, Mayer JD, Lorton C, Rabinowitz PM.   +10 more
europepmc   +1 more source