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L'autrycide et l'avenir de l'élevage africain
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Georges Curasson
doaj +1 more source
Trypanocidal Essential Oils: A Review
Trypanosomiases are diseases caused by parasitic protozoan trypanosomes of the genus Trypanosoma. In humans, this includes Chagas disease and African trypanosomiasis. There are few therapeutic options, and there is low efficacy to clinical treatment. Therefore, the search for new drugs for the trypanosomiasis is urgent. This review describes studies of
Mayara Castro de Morais +4 more
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Biogenic trypanocidal sesquiterpenes: lead compounds to design future trypanocidal drugs - a mini review [PDF]
Abstract Human trypanosomiasis is a parasitic disease among poor people in Africa and Latin America. Therapy against African and American trypanosomiasis is based on a few drugs that often cause severe side-effects. Therefore, it is essential to develop drug discovery especially from natural origins. Sesquiterpenes, a diverse group of natural
Saeidnia, Soodabeh +2 more
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Green fluorescent diamidines as diagnostic probes for trypanosomes [PDF]
LED fluorescence microscopy offers potential benefits to the diagnosis of human African trypanosomiasis, as well as to other aspects of diseases management, such as detection of drug resistant strains.
Arvind Kumar +27 more
core +1 more source
L'efficacité du furazolidone contre les infections expérimentales à Trypanosoma evansi a été étudiée chez les dromadaires et les souris. Les critères de mise en évidence de l'effet trypanocide du furazolidone comprenaient la recherche de T.
B.H. Ali, T. Hassan, K.H. Malik
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Background In Ethiopia, veterinary pharmaceuticals and agricultural pesticides are vital to maintaining agricultural productivity and food security, yet their quality and safety regulation face significant challenges. Objectives This study aimed to assess the regulatory framework, institutional capacity, and routine quality assurance practices related ...
Yesuneh Tefera Mekasha +8 more
wiley +1 more source
L'auteur a étudié le comportement, in vitro, de T. evansi en présence de 23 acides aminés et de 13 de leurs dérivés. Le glutathion, la cysteine et les composés possédant un groupement S H dans leur molécule interviennent très activement dans les ...
J. Balis
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Trypanocidal Activity of Aziridinyl Nitrobenzamide Prodrugs [PDF]
ABSTRACT The trypanocidal agents nifurtimox and benznidazole both function as prodrugs and must undergo enzyme-mediated activation, a reaction catalyzed by type I nitroreductase (NTR). In the search for new parasitic therapies, we have utilized this finding to investigate whether aziridinyl nitrobenzamide derivatives have ...
Bot, C +5 more
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Natural Products from Mexican Medicinal Plants as Promising Trypanocidal Drugs
Chagas disease (American Trypanosomiasis) is caused by the protozoan Trypanosoma cruzi. Worldwide it is one of the seventeen neglected tropical diseases. There is a need of new drugs. This review assesses the literature (2012‐2024) of secondary metabolites isolated from Mexican plants active against this parasite.
Karla Daniela Rodríguez‐Hernández +2 more
wiley +1 more source
Chagas disease is a public health problem affecting approximately seven million people worldwide. Thus, there is a need to discover drugs for the adequate treatment of this disease because currently available drugs have serious side effects.
Suziene Caroline Silva Cardoso +14 more
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