Results 31 to 40 of about 1,868 (198)

Assessment of animal African trypanosomiasis (AAT) vulnerability in cattle-owning communities of sub-Saharan Africa [PDF]

, 2016
Background: Animal African trypanosomiasis (AAT) is one of the biggest constraints to livestock production and a threat to food security in sub-Saharan Africa.
A Hagos, A Mamoudou, A Mamoudou, A Mamoudou, A Miruk, A Soudré, A Sow, A Teko-Agbo, APM Shaw, C Waiswa, C. Mumba, D Grace, D Muhanguzi, EH Waaij van der, G Cecchi, G Hendrickx, G Rowlands, G. B. Napier, GA Vale, GK Fuller, H Buyst, H Simukoko, H. R. Holt, J Bouyer, J McDermott, J Woodford, J. Guitian, L Sinyangwe, M Abdoulmoumini, M Chanie, M Pinder, M Simon-Grifé, MJB Vreysen, N Machila, N Machila, NE Anderson, OD Cardona, P Bossche Van den, P Solano, PP Simarro, R Fikru, R Selby, R. Selby, S Costard, S Tasew, V Delespaux   +45 more
core   +5 more sources

Essai de l’efficacité du Cymelarsan™ sur Trypanosoma evansi chez le dromadaire

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1989
L’expérimentation au Niger d’une nouvelle molécule arsenicale, susceptible d’être utilisée dans le traitement de la trypanosomose cameline à Trypanosoma evansi a démontré, au cours d’un essai d’efficacité effectué sur 8 jeunes dromadaires infestés ...
Pierre Tager-Kagan, Jacques Itard, M. Clair   +2 more
doaj   +1 more source

Trypanocidal Activity of Flavanone Derivatives [PDF]

Molecules, 2020
Chagas disease, also known as American trypanosomiasis, is classified as a neglected disease by the World Health Organization. For clinical treatment, only two drugs have been on the market, Benznidazole and Nifurtimox, both of which are recommended for use in the acute phase but present low cure rates in the chronic phase.
Gabriela Maciel Diogo, Josimara Souza Andrade, Policarpo Ademar Sales Junior, Silvane Maria Fonseca Murta, Viviane Martins Rebello Dos Santos, Jason Guy Taylor   +5 more
openaire   +3 more sources

Sensibilité aux trypanocides et au plasma humain de souches de Trypanozoon isolées d’animaux provenant de foyers endémiques de maladie du sommeil au Nigeria

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1995
La sensibilité de douze souches de Trypanozoon isolées de bovins semi-nomades provenant de foyers endémiques connus de maladie du sommeil situés dans le Centre et au Nord du Nigeria a été étudiée vis-à-vis de deux trypanocides, l'acéturate de diminazène (
A.I. Kalu
doaj   +1 more source

Immunomodulatory, trypanocide, and antioxidant properties of essential oil fractions of Lippia alba (Verbenaceae)

BMC Complementary Medicine and Therapies, 2021
Background Parasite persistence, exacerbated and sustained immune response, and continuous oxidative stress have been described to contribute to the development of the cardiac manifestations in Chronic Chagas Disease. Nevertheless, there are no efficient
Wendy Lorena Quintero, Erika Marcela Moreno, Sandra Milena Leal Pinto, Sandra Milena Sanabria, Elena Stashenko, Liliana Torcoroma García   +5 more
doaj   +1 more source

Anti-Trypanosoma cruzi action of a new benzofuran derivative based on amiodarone structure [PDF]

, 2018
Chagas disease is a neglected tropical affection caused by the protozoan parasite Trypanosoma cruzi. There is no current effective treatment since the only two available drugs have a limited efficacy and produce side effects.
Benaim, Gustavo, Hejchman, Elżbieta, Hernández Rodríguez, Vanessa, Pinto Martinez, Andrea, Rodríguez Durán, Jessica Jenireth   +4 more
core   +1 more source

Chloroplast nucleoids are highly dynamic in ploidy, number, and structure during angiosperm leaf development

The Plant Journal, Volume 102, Issue 4, Page 730-746, May 2020., 2020
Summary Chloroplast nucleoids are large, compact nucleoprotein structures containing multiple copies of the plastid genome. Studies on structural and quantitative changes of plastid DNA (ptDNA) during leaf development are scarce and have produced controversial data.
Stephan Greiner, Hieronim Golczyk, Irina Malinova, Tommaso Pellizzer, Ralph Bock, Thomas Börner, Reinhold G. Herrmann   +6 more
wiley   +1 more source

Antitrypanosomal Activity and Molecular Docking Studies of Lobetyolin From Lobelia rhynchopetalum Hemsl. Root Extract Against Trypanosoma congolense Field Isolates [PDF]

Biomed Res Int
Currently available drugs for trypanosomiasis are few, and their use is limited by toxicity and growing resistance. This highlights the need for safer and more effective alternatives. In this study, the in vitro and in vivo antitrypanosomal activities of an 80% methanol root extract of Lobelia rhynchopetalum and its major constituent were evaluated ...
Yimer S, Tewelde E, Bisrat D, Tadesse S, Yeshak M.   +4 more
europepmc   +2 more sources

Combining tubercidin and cordycepin scaffolds results in highly active candidates to treat late-stage sleeping sickness

Nature Communications, 2019
Trypanosoma brucei relies on uptake and conversion of purines from the host, which constitutes a potential drug target. Here, Hulpia et al. combine structural elements from known trypanocidal nucleoside analogues and develop a potent trypanocide with ...
Fabian Hulpia, Dorien Mabille, Gustavo D. Campagnaro, Gabriela Schumann, Louis Maes, Isabel Roditi, Anders Hofer, Harry P. de Koning, Guy Caljon, Serge Van Calenbergh   +9 more
doaj   +1 more source

Green fluorescent diamidines as diagnostic probes for trypanosomes [PDF]

, 2014
LED fluorescence microscopy offers potential benefits to the diagnosis of human African trypanosomiasis, as well as to other aspects of diseases management, such as detection of drug resistant strains.
Arvind Kumar, Bailey, Baker, Barrett, Bieler, Bridges, Carter, Chappuis, David W. Boykin, de Koning, Federica Giordani, Hanscheid, Jones, Keiser, Lanteri, Manoj Munde, Mathis, Mathis, Matovu, Michael P. Barrett, Minion, Mohamed A. Ismail, Paine, Steingart, Stewart, Vincent, W. David Wilson, Wilson   +27 more
core   +1 more source