Results 51 to 60 of about 611 (151)

Spatiotemporal changes in prevalence of Sodalis glossinidius, Spiroplasma spp. and trypanosome species in wild Glossina tachinoides from Sora‐Mboum animal African trypanosomiasis focus in northern Cameroon

Insect Science, Volume 32, Issue 5, Page 1713-1725, October 2025.
Abstract Sterile Insect Technique (SIT) has proven effective to reduce tsetse population density in large infected areas where animal African trypanosomosis (AAT) and human African trypanosomiasis (HAT) elimination was difficult to achieve. However, the decrease in mass production of insectary‐reared tsetse and the limited but incomplete knowledge on ...
Steve Feudjio Soffack, Tito T. Melachio Tanekou, Hugues C. Nana Djeunga, Oumarou Farikou, Ginette I. Kame Ngasse, Mureille C. Tchami Mbagnia, Murielle Wondji, Charles S. Wondji, Hager Khalil, Adly M. M. Abd‐Alla, Anne Geiger, Gustave Simo, Flobert Njiokou   +12 more
wiley   +1 more source

Immune Response in Cattle Trypanosomosis and Trypanotolerance: Main Findings and Gaps

Parasite Immunology, Volume 46, Issue 11, November 2024.
ABSTRACT Trypanosome parasites of the genus Trypanosoma cause African animal trypanosomosis, a devastating livestock disease plaguing sub‐Saharan Africa. Unlike many protozoan parasites, these extracellular blood‐borne pathogens directly engage the host's immune system. While the mouse model has provided valuable insights, a comprehensive understanding
Gnohion Fabrice Somé, Modou Séré, Bienvenu Martin Somda, Guiguigbaza‐Kossigan Dayo, Georges Anicet Ouédraogo, Alain Boulangé, Ghizlane Maarifi, Isabelle Chantal, David Berthier‐Teyssedre, Sophie Thévenon   +9 more
wiley   +1 more source

Cytotoxicity and trypanocidal activity of nifurtimox encapsulated in ethylcyanoacrylate nanoparticles

Biological Research, 2002
The aim of the present study was to study the trypanocidal activity of nanoparticles loaded with nifurtimox in comparison with the free drug against Trypanosoma cruzi, responsible for Chagas' disease.
GITTITH SÁNCHEZ, DANIELA CUELLAR, INES ZULANTAY, MARTA GAJARDO, GUILLERMO GONZÁLEZ-MARTIN   +4 more
doaj  

Note sur la toxicité de l'Isométamidium par injection intraveineuse chez quelques mammifères domestiques et spécialement chez le dromadaire

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1977
Le chlorhydrate de chlorure d'Isométamidium est très mal supporté par le dromadaire à des doses supérieures à 1 mg/kg administrées par la voie ...
J. Balis
doaj   +1 more source

Tractable Quinolone Hydrazides Exhibiting Sub‐Micromolar and Broad Spectrum Antitrypanosomal Activities

ChemMedChem, Volume 19, Issue 9, May 2, 2024.
Several (sub)species of Trypanosoma are responsible for human African trypanosomiasis (HAT), Chagas disease, and Nagana. These (sub)species have different drug susceptibility profiles. This work reports several easily accessed quinolone hydrazides exhibiting sub‐micromolar activities against multiple (sub)species of Trypanosoma.
Kgothatso A. Chirwa, Karol R. Francisco, Phelelisiwe S. Dube, Hayoung Park, Lesetja J. Legoabe, Thaiz Rodrigues Teixeira, Conor R. Caffrey, Richard M. Beteck   +7 more
wiley   +1 more source

Cinétique des anticorps après traitement trypanocide chez des bovins infectés expérimentalement ou naturellement. Intérêt épidémiologique

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1990
La cinétique des anticorps anti-trypanosomes a été étudiée en immunofluorescen ce indirecte (IFI) et en ELISA chez des bovins infectés expérimentalement par Trypanosoma congolense ou naturellement dans une zone à forte pression glossinaire.
R. Bocquentin, P. Very, Gérard Duvallet
doaj   +1 more source

Trypanocide counterfeits

The script supports Chapter 5 subsection 2 titled: “Trypanocide advancements and challenges in Uganda” from my PhD thesis titled: Exploring trypanocide resistance: Lessons from Uganda (2024). This describes data (referenced as “trypCounterfeit”) were the quality of trypanocides i.e., diminazene aceturate (DA), isometamidium chloride (ISM) and homidium ...
Kasozi, Keneth Iceland, MacLeod, Ewan Thomas, Welburn, Susan Christina   +2 more
openaire   +2 more sources

Evaluating 5-Nitrothiazoles as Trypanocidal Agents [PDF]

Antimicrobial Agents and Chemotherapy, 2016
ABSTRACTThe growth-inhibitory properties of a 5-nitrothiazole series were evaluated againstTrypanosoma brucei. A subset of related compounds displayed the greatest potency toward the parasite while exhibiting little cytotoxic effect on mammalian cells, with this antiparasitic activity dependent on expression of a type I nitroreductase by the ...
O'Shea, IP, Shahed, M, Aguilera-Venegas, B, WILKINSON, SR   +3 more
openaire   +3 more sources

DFMO inhibition of neuroblastoma tumorigenesis

Cancer Medicine, Volume 13, Issue 9, May 2024.
Abstract Background Most high‐risk neuroblastoma patients who relapse succumb to disease despite the existing therapy. We recently reported increased event‐free and overall survival in neuroblastoma patients receiving difluoromethylornithine (DFMO) during maintenance therapy.
Divya Gandra, David H. Mulama, David M. Foureau, Kimberly Q. McKinney, Elizabeth Kim, Kaitlyn Smith, Jason Haw, Abhinav Nagulapally, Giselle L. Saulnier Sholler   +8 more
wiley   +1 more source

Infection expérimentale de zébus guyanais avec Trypanosoma vivax

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1990
La souche guyanaise de Trypanosoma vivax est pathogène pour le zébu guyanais de type Brahman : l'infection expérimentale de 19 bovins, agés d'un an, s'est traduite par de la fièvre (peu élevée et transitoire), une chute de l'hématocrite et une perte de ...
Emmanuel Camus, Arnaud Martrenchar
doaj   +1 more source