Results 61 to 70 of about 1,868 (198)

Spatiotemporal changes in prevalence of Sodalis glossinidius, Spiroplasma spp. and trypanosome species in wild Glossina tachinoides from Sora‐Mboum animal African trypanosomiasis focus in northern Cameroon

Insect Science, Volume 32, Issue 5, Page 1713-1725, October 2025.
Abstract Sterile Insect Technique (SIT) has proven effective to reduce tsetse population density in large infected areas where animal African trypanosomosis (AAT) and human African trypanosomiasis (HAT) elimination was difficult to achieve. However, the decrease in mass production of insectary‐reared tsetse and the limited but incomplete knowledge on ...
Steve Feudjio Soffack, Tito T. Melachio Tanekou, Hugues C. Nana Djeunga, Oumarou Farikou, Ginette I. Kame Ngasse, Mureille C. Tchami Mbagnia, Murielle Wondji, Charles S. Wondji, Hager Khalil, Adly M. M. Abd‐Alla, Anne Geiger, Gustave Simo, Flobert Njiokou   +12 more
wiley   +1 more source

Design, synthesis and identification of novel molecular hybrids based on naphthoquinone aromatic hydrazides as potential trypanocide and leishmanicidal agents

Anais da Academia Brasileira de Ciências
In pursuit of potential agents to treat Chagas disease and leishmaniasis, we report the design, synthesis, and identification novel naphthoquinone hydrazide-based molecular hybrids.
ROSANE D. CEZAR, ADRIANO O. DA SILVA, ROSÂNGELA S. LOPES, CELSO V. NAKAMURA, JEAN HENRIQUE S. RODRIGUES, ESTELA MARIANA G. LOURENÇO, SUMBAL SABA, ADILSON BEATRIZ, JAMAL RAFIQUE, DÊNIS P. DE LIMA   +9 more
doaj   +1 more source

Action trypanocide du chlorhydrate de chlorure d'Isométamidium (+) sur Trypanosoma evansi et essai de traitement de la trypanosomiase du dromadaire [PDF]

, 1977
Le chlorhydrate de chlorure d'Isométamidium est doué de peu d'activité à l'égard de Trypanosoma evansi. En l'absence de produits plus actifs, son utilisation chez le dromadaire par injection intraveineuse ou intramusculaire à des doses comprises entre 0 ...
Balis, J., Richard, Didier
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Immune Response in Cattle Trypanosomosis and Trypanotolerance: Main Findings and Gaps

Parasite Immunology, Volume 46, Issue 11, November 2024.
ABSTRACT Trypanosome parasites of the genus Trypanosoma cause African animal trypanosomosis, a devastating livestock disease plaguing sub‐Saharan Africa. Unlike many protozoan parasites, these extracellular blood‐borne pathogens directly engage the host's immune system. While the mouse model has provided valuable insights, a comprehensive understanding
Gnohion Fabrice Somé, Modou Séré, Bienvenu Martin Somda, Guiguigbaza‐Kossigan Dayo, Georges Anicet Ouédraogo, Alain Boulangé, Ghizlane Maarifi, Isabelle Chantal, David Berthier‐Teyssedre, Sophie Thévenon   +9 more
wiley   +1 more source

Trypanosoma evansi and Surra: A review and perspectives on transmission, epidemiology and control, impact, and zoonotic aspects [PDF]

, 2013
This paper reviews the transmission modes of Trypanosoma evansi. Its worldwide distribution is attributed to mechanical transmission. While the role of tabanids is clear, we raise questions on the relative role of Haematobia sp.
Dargantes, Alan, Desquesnes, Marc, Holzmuller, Philippe, Jittapalapong, Sathaporn, Lai, De-Hua, Lun, Zhao-Rong   +5 more
core   +3 more sources

Tractable Quinolone Hydrazides Exhibiting Sub‐Micromolar and Broad Spectrum Antitrypanosomal Activities

ChemMedChem, Volume 19, Issue 9, May 2, 2024.
Several (sub)species of Trypanosoma are responsible for human African trypanosomiasis (HAT), Chagas disease, and Nagana. These (sub)species have different drug susceptibility profiles. This work reports several easily accessed quinolone hydrazides exhibiting sub‐micromolar activities against multiple (sub)species of Trypanosoma.
Kgothatso A. Chirwa, Karol R. Francisco, Phelelisiwe S. Dube, Hayoung Park, Lesetja J. Legoabe, Thaiz Rodrigues Teixeira, Conor R. Caffrey, Richard M. Beteck   +7 more
wiley   +1 more source

Cytotoxicity and trypanocidal activity of nifurtimox encapsulated in ethylcyanoacrylate nanoparticles

Biological Research, 2002
The aim of the present study was to study the trypanocidal activity of nanoparticles loaded with nifurtimox in comparison with the free drug against Trypanosoma cruzi, responsible for Chagas' disease.
GITTITH SÁNCHEZ, DANIELA CUELLAR, INES ZULANTAY, MARTA GAJARDO, GUILLERMO GONZÁLEZ-MARTIN   +4 more
doaj  

Note sur la toxicité de l'Isométamidium par injection intraveineuse chez quelques mammifères domestiques et spécialement chez le dromadaire

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1977
Le chlorhydrate de chlorure d'Isométamidium est très mal supporté par le dromadaire à des doses supérieures à 1 mg/kg administrées par la voie ...
J. Balis
doaj   +1 more source

DFMO inhibition of neuroblastoma tumorigenesis

Cancer Medicine, Volume 13, Issue 9, May 2024.
Abstract Background Most high‐risk neuroblastoma patients who relapse succumb to disease despite the existing therapy. We recently reported increased event‐free and overall survival in neuroblastoma patients receiving difluoromethylornithine (DFMO) during maintenance therapy.
Divya Gandra, David H. Mulama, David M. Foureau, Kimberly Q. McKinney, Elizabeth Kim, Kaitlyn Smith, Jason Haw, Abhinav Nagulapally, Giselle L. Saulnier Sholler   +8 more
wiley   +1 more source

Infection expérimentale de zébus guyanais avec Trypanosoma vivax [PDF]

, 1990
La souche guyanaise de Trypanosoma vivax est pathogène pour le zébu guyanais de type Brahman : l'infection expérimentale de 19 bovins, agés d'un an, s'est traduite par de la fièvre (peu élevée et transitoire), une chute de l'hématocrite et une perte de ...
Camus, Emmanuel, Martrenchar, Arnaud
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