Results 141 to 150 of about 102,275 (301)

Insect Stage-Specific Receptor Adenylate Cyclases Are Localized to Distinct Subdomains of the Trypanosoma brucei Flagellar Membrane

Eukaryotic Cell, 2014
Increasing evidence indicates that the Trypanosoma brucei flagellum (synonymous with cilium) plays important roles in host-parasite interactions. Several studies have identified virulence factors and signaling proteins in the flagellar membrane of ...
Edwin A. Saada, Z. Kabututu, Miguel A. Lopez, Michelle M. Shimogawa, Gerasimos Langousis, M. Oberholzer, A. Riestra, Z. Jónsson, J. Wohlschlegel, K. Hill   +9 more
semanticscholar   +1 more source

Résistance médicamenteuse d'isolats récents de Trypanosoma brucei et Trypanosoma congolense

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1988
Des études ont été menées sur des souris pour déterminer la sensibilité aux médicaments d’isolats récents de Trypanosoma brucei et Trypanosoma congolense. Chacune des onze souches de T. congolense et des cinq souches de T. brucei, toutes isolées sur des
R.A. Joshua
doaj   +1 more source

Modes of flagellar assembly in Chlamydomonas reinhardtii and Trypanosoma brucei

eLife, 2014
Defects in flagella growth are related to a number of human diseases. Central to flagellar growth is the organization of microtubules that polymerize from basal bodies to form the axoneme, which consists of hundreds of proteins.
J. Höög, J. Höög, Sylvain Lacomble, E. O'Toole, A. Hoenger, J. McIntosh, K. Gull   +6 more
semanticscholar   +1 more source

Human infectivity trait in Trypanosoma brucei: stability, heritability and relationship to sra expression [PDF]

, 2004
Some Trypanosoma brucei lines infect humans whereas others do not because the parasites are lysed by human serum. We have developed a robust, quantitative in vitro assay based on differential uptake of fluorescent dyes by live and dead trypanosomes to ...
Bisoni, L., Lindergard, L.A.G., MacLeod, A., McLellan, S., Tait, A., Turner, C.M.R.   +5 more
core   +1 more source

The ever unfolding story of cAMP signaling in trypanosomatids: vive la difference! [PDF]

, 2015
Kinetoplastids are unicellular, eukaryotic, flagellated protozoans containing the eponymous kinetoplast. Within this order, the family of trypanosomatids are responsible for some of the most serious human diseases, including Chagas disease (Trypanosoma ...
De Koning, Harry P., Kalejaiye, Titilola D., Tagoe, Daniel N. A.   +2 more
core   +1 more source

Responses of Domestic Animals to Infections of Trypanosoma vivax, T. congolense and T. brucei [PDF]

, 1956
E. E. Edwards, J. M. Judd, F. A. Squire
openalex   +1 more source

The Design and Synthesis of Potent and Selective Inhibitors of Trypanosoma brucei Glycogen Synthase Kinase 3 for the Treatment of Human African Trypanosomiasis

Journal of Medicinal Chemistry, 2014
Glycogen synthase kinase 3 (GSK3) is a genetically validated drug target for human African trypanosomiasis (HAT), also called African sleeping sickness. We report the synthesis and biological evaluation of aminopyrazole derivatives as Trypanosoma brucei ...
R. Urich, Raffaella Grimaldi, Torsten Luksch, J. Frearson, R. Brenk, P. Wyatt   +5 more
semanticscholar   +1 more source

Ein für Trypanosoma Brucei specifisches Serum und seine Einwirkung auf Trypanosoma gambiense [PDF]

, 1906
F. K. Kleine, B. Möllers
openalex   +1 more source

Genome and Phylogenetic Analyses of Trypanosoma evansi Reveal Extensive Similarity to T. brucei and Multiple Independent Origins for Dyskinetoplasty

PLoS Neglected Tropical Diseases, 2015
Two key biological features distinguish Trypanosoma evansi from the T. brucei group: independence from the tsetse fly as obligatory vector, and independence from the need for functional mitochondrial DNA (kinetoplast or kDNA).
J. Carnes, Atashi Anupama, O. Balmer, A. Jackson, M. Lewis, Robert Brown, Igor Cestari, M. Desquesnes, Claire Gendrin, C. Hertz-Fowler, H. Imamura, A. Ivens, Ludek Koreny, D. Lai, A. MacLeod, Suzanne M. McDermott, C. Merritt, S. Monnerat, W. Moon, P. Myler, I. Phan, Gowthaman Ramasamy, D. Sivam, Z. Lun, J. Lukeš, K. Stuart, A. Schnaufer   +26 more
semanticscholar   +1 more source

Trypanosome diseases of domestic animals in Uganda II.—Trypanosoma brucei ( Plimmer and Bradford ) [PDF]

, 1910
David Bruce, A. E. Hamerton, H. R. Bateman, F. P. Mackie   +3 more
openalex   +1 more source