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The nuclear proteome of Trypanosoma brucei [PDF]
Trypanosoma brucei is a protozoan flagellate that is transmitted by tsetse flies into the mammalian bloodstream. The parasite has a huge impact on human health both directly by causing African sleeping sickness and indirectly, by infecting domestic ...
Carina Goos+4 more
semanticscholar +6 more sources
Whole-Genome Sequencing of
Human African trypanosomiasis is caused by two subspecies of Trypanosoma brucei. Trypanosoma brucei rhodesiense is found in East Africa and frequently causes acute disease, while Trypanosoma brucei gambiense is found in West Africa and is associated with
Ian Goodhead+10 more
doaj +5 more sources
Differences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by Trypanolytic factor 1 [PDF]
<p><b>Background:</b> The three sub-species of <i>Trypanosoma brucei</i> are important pathogens of sub-Saharan Africa. <i>T. b.
A Cooper+77 more
core +21 more sources
Therapeutic Strategies against Leishmania and Trypanosoma
Human African trypanosomiasis (also known as sleeping sickness, with Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense as etiological agents), American trypanosomiasis (also known as Chagas disease, with Trypanosoma cruzi as the etiological
André L. S. Santos+5 more
doaj +1 more source
The exosome of Trypanosoma brucei [PDF]
The yeast exosome is a complex of at least 10 essential 3'-5' riboexonucleases which is involved in 3'-processing of many RNA species. An exosome-like complex has been found or predicted to exist in other eukaryotes but not in Escherichia coli. The unicellular parasite Trypanosoma brucei diverged very early in eukaryotic evolution.
Antonio M. Estévez+2 more
openaire +3 more sources
The exopolyphosphatase TbrPPX1 of Trypanosoma brucei [PDF]
Abstract Background Exopolyphosphatases and pyrophosphatases play important but still incompletely understood roles in energy metabolism, and also in other aspects of cell biology such as osmoregulation or signal transduction.
Luginbuehl, Edith+4 more
openaire +5 more sources
Signatures of hybridization in Trypanosoma brucei [PDF]
Genetic exchange among disease-causing micro-organisms can generate progeny that combine different pathogenic traits. Though sexual reproduction has been described in trypanosomes, its impact on the epidemiology of Human African Trypanosomiasis (HAT) remains controversial.
Christopher Kay+3 more
openaire +5 more sources
On The Cultivation Of Trypanosoma Brucei [PDF]
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Novy, F. G., McNeal, W. J.
openaire +2 more sources
Vacuolar ATPase depletion contributes to dysregulation of endocytosis in bloodstream forms of Trypanosoma brucei [PDF]
BACKGROUND Vacuolar H-ATPase (V-ATPase) is a highly conserved protein complex which hydrolyzes ATP and pumps protons to acidify vacuolar vesicles.
Hide, G+4 more
core +2 more sources