Results 91 to 100 of about 50,586 (204)
Journal of Microscopy, Volume 301, Issue 2, Page 222-240, February 2026.Abstract Kinetoplastid parasites include several species. Trypanosoma brucei causes African sleeping sickness in humans and a wasting disease nagana in livestock. Trypanosoma cruzi is the causative agent of Chagas disease and Leishmania species cause leishmaniasis, which can present with visceral, cutaneous, or mucocutaneous symptoms.
Heidi Anderson +2 more
wiley +1 more source
Trypanosoma Infection Favors Brucella Elimination via IL-12/IFNγ-Dependent Pathways
Frontiers in Immunology, 2017 This study develops an original co-infection model in mice using Brucella melitensis, the most frequent cause of human brucellosis, and Trypanosoma brucei, the agent of African trypanosomiasis. Although the immunosuppressive effects of T.
Arnaud Machelart +11 more
doaj +1 more source
Genetic exchange in Trypanosoma brucei: evidence for mating prior to metacyclic stage development [PDF]
, 2005 It is well established that genetic exchange occurs between Trypanosoma brucei parasites when two stocks are used to infect tsetse flies under laboratory conditions and a number of such crosses have been undertaken.
Alison Tweedie +22 more
core +2 more sources
Cortisol Regulates PD‐1 and IL‐12 in Canine Leishmaniasis
Parasite Immunology, Volume 48, Issue 2, February 2026.ABSTRACT Canine visceral leishmaniasis (CanL) is a tropical zoonosis caused by Brazil's protozoan Leishmania (L.) infantum. Disorders in the hypothalamic–pituitary–adrenal (HPA) axis have been reported in human and experimental visceral leishmaniasis, but not yet in canine leishmaniasis.
Lucas Takeshi Siqueira Ito +6 more
wiley +1 more source
Résistance médicamenteuse d'isolats récents de Trypanosoma brucei et Trypanosoma congolense
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1988 Des études ont été menées sur des souris pour déterminer la sensibilité aux médicaments d’isolats récents de Trypanosoma brucei et Trypanosoma congolense. Chacune des onze souches de T. congolense et des cinq souches de T. brucei, toutes isolées sur des
R.A. Joshua
doaj +1 more source
MIF contributes to Trypanosoma brucei associated immunopathogenicity development [PDF]
, 2014 African trypanosomiasis is a chronic debilitating disease affecting the health and economic well-being of many people in developing countries. The pathogenicity associated with this disease involves a persistent inflammatory response, whereby M1-type ...
Beschin, Alain +11 more
core +4 more sources
Molecular Insights into Fungal Glycosylphosphatidylinositol Transamidase Complex
Advanced Science, Volume 13, Issue 2, 9 January 2026.The glycosylphosphatidylinositol (GPI) biosynthesis pathway is critical for antifungal drug development. This study reports three cryo‐electron microscopy structures of fungal GPI transamidase (GPIT), captured in two substrate‐bound states and a novel dimeric assembly.
Zhengkang Hua +12 more
wiley +1 more source
Trypanosoma brucei infection protects mice against malaria.
PLoS Pathogens, 2019 Sleeping sickness and malaria are parasitic diseases with overlapping geographical distributions in sub-Saharan Africa. We hypothesized that the immune response elicited by an infection with Trypanosoma brucei, the etiological agent of sleeping sickness,
Margarida Sanches-Vaz +8 more
doaj +1 more source
Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.In vitro trypanocidal activity of a polyprenylated benzophenone‐enriched Brazilian red propolis extract (SEBz) and its major constituents, guttiferone E/xanthochymol (GUT/XAN) and oblongifolin B (OBL), exhibit in vitro trypanocidal activity against Trypanosoma cruzi, inducing ultrastructural damage with moderate cytotoxicity and no significant ...
Nicoli Dias Oliveira +9 more
wiley +1 more source