Results 11 to 20 of about 69,743 (296)

Differences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by Trypanolytic factor 1 [PDF]

, 2011
<p><b>Background:</b> The three sub-species of <i>Trypanosoma brucei</i> are important pathogens of sub-Saharan Africa. <i>T. b.
A Cooper, A Tait, AM Shiflett, AM Shiflett, Annette MacLeod, AP Jackson, AP Jackson, B Vanhollebeke, B Vanhollebeke, B Vanhollebeke, C De Greef, C De Greef, C De Greef, C. Michael R. Turner, CM Turner, D Mehlitz, D Salmon, D Steverding, D Steverding, DG Godfrey, DJ Grab, E Pays, E Pays, F Bringaud, F Mathieu-daude, G Hide, G Hide, H Hirumi, HV Xong, J Barry, J Drain, J Lukes, J Raper, J Seed, J Widener, Jayne Raper, JC Enyaru, JC Ortiz, JM Harrington, JR Stevens, K Hager, KJ Livak, L Lecordier, L Vanhamme, LJ Morrison, M Becker, M Becker, M Berberof, M Berriman, M Kaern, M Ligtenberg, M Radwanska, Matthew Berriman, MP Molina-Portela, MR Rifkin, Nicola J. Veitch, NM Page, O Balmer, P Molina-Portela Mdel, P Paindavoine, P Poelvoorde, P Truc, Paul Capewell, Philippe Büscher, R Kieft, R Thomson, R Young, S Rozen, SC Welburn, SD Faulkner, SL Hajduk, Stephen L. Hajduk, U Zillmann, V Jamonneau, W Gibson, WC Gibson, WC Gibson, WC Gibson   +77 more
core   +15 more sources

Molecular identification of Trypanosoma brucei brucei and in vitro anti-trypanosomal activity of different parts of methanolic extract of Senna occidentalis

Clinical Phytoscience, 2020
Objective The present study investigated the anti-Trypanosoma brucei brucei activity of methanolic extract of Senna occidentalis roots, leaves, stem bark, and seed in vitro and bioactive components of the most active plant part.
Zainab Aliyu Alhafiz, Mohammed Sani Abdulsalami, Mohammed Auwal Ibrahim, Timothy Bulus, Ahmed Babangida Suleiman   +4 more
doaj   +1 more source

Therapeutic Strategies against Leishmania and Trypanosoma

Pathogens, 2023
Human African trypanosomiasis (also known as sleeping sickness, with Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense as etiological agents), American trypanosomiasis (also known as Chagas disease, with Trypanosoma cruzi as the etiological
André L. S. Santos, Igor A. Rodrigues, Claudia M. d’Avila-Levy, Cátia L. Sodré, Koert Ritmeijer, Marta H. Branquinha   +5 more
doaj   +1 more source

Genome-wide subcellular protein map for the flagellate parasite Trypanosoma brucei

Nature Microbiology, 2023
Trypanosoma   brucei is a model trypanosomatid, an important group of human, animal and plant unicellular parasites. Understanding their complex cell architecture and life cycle is challenging because, as with most eukaryotic microbes, ~50% of genome ...
K. Billington, C. Halliday, Ross Madden, P. Dyer, A. Barker, F. Moreira-Leite, M. Carrington, S. Vaughan, C. Hertz-Fowler, Samuel Dean, J. Sunter, R. Wheeler, K. Gull   +12 more
semanticscholar   +1 more source

The exosome of Trypanosoma brucei [PDF]

The EMBO Journal, 2001
The yeast exosome is a complex of at least 10 essential 3'-5' riboexonucleases which is involved in 3'-processing of many RNA species. An exosome-like complex has been found or predicted to exist in other eukaryotes but not in Escherichia coli. The unicellular parasite Trypanosoma brucei diverged very early in eukaryotic evolution.
Antonio M. Estévez, Tore Kempf, Christine Clayton   +2 more
openaire   +3 more sources

Antitrypanosomal activity of Argemone mexicana extract and fractions in the animal model of Trypanosoma brucei brucei infection

Open Veterinary Science, 2022
This study investigated the antitrypanosomal activity of Argemone mexicana extract and fractions in the animal model of Trypanosoma brucei brucei infection.
Chukwu Ifeoma L., Ugwu Malachy C., Iroha Ifeanyi R., Mbagwu Ikechukwu S., Okafor Ugochukwu U., Ajaghaku Amara A.   +5 more
doaj   +1 more source

Transport of  -Aminoisobutyrate into Trypanosoma brucei brucei [PDF]

Microbiology, 1984
The uptake of alpha-aminoisobutyrate (AIB) by washed cell suspensions of bloodstream forms of Trypanosoma brucei brucei has been shown to be an energy-dependent process. No metabolism of AIB was detected under conditions leading to a 100-fold accumulation of AIB within the organism. Kinetic studies revealed that AIB uptake involved two components; that
K. P. Coolbear, M. Midgley
openaire   +3 more sources

Epidemiology of Trypanosomiasis in Wildlife—Implications for Humans at the Wildlife Interface in Africa

Frontiers in Veterinary Science, 2021
While both human and animal trypanosomiasis continue to present as major human and animal public health constraints globally, detailed analyses of trypanosome wildlife reservoir hosts remain sparse.
Keneth Iceland Kasozi, Keneth Iceland Kasozi, Gerald Zirintunda, Fred Ssempijja, Bridget Buyinza, Khalid J. Alzahrani, Kevin Matama, Helen N. Nakimbugwe, Helen N. Nakimbugwe, Luay Alkazmi, David Onanyang, Paul Bogere, Juma John Ochieng, Saher Islam, Wycliff Matovu, David Paul Nalumenya, Gaber El-Saber Batiha, Lawrence Obado Osuwat, Mahmoud Abdelhamid, Tianren Shen, Tianren Shen, Leonard Omadang, Susan Christina Welburn, Susan Christina Welburn   +23 more
doaj   +1 more source

The exopolyphosphatase TbrPPX1 of Trypanosoma brucei [PDF]

BMC Microbiology, 2011
Abstract Background Exopolyphosphatases and pyrophosphatases play important but still incompletely understood roles in energy metabolism, and also in other aspects of cell biology such as osmoregulation or signal transduction.
Luginbuehl, Edith, Kunz, Stefan, Wentzinger, Laurent, Freimoser, Florian, Seebeck, Thomas   +4 more
openaire   +5 more sources

Molecular variation of Trypanosoma brucei subspecies as revealed by AFLP fingerprinting [PDF]

, 2002
Genetic analysis of Trypanosoma spp. depends on the detection of variation between strains. We have used the amplified fragment length polymorphism (AFLP) technique to develop a convenient and reliable method for genetic characterization of Trypanosome ...
Agbo, E.E.C., Claassen, H.J.H.M., Majiwa, P.A.O., Pas, M.F.W., te   +3 more
core   +10 more sources