Results 21 to 30 of about 59,489 (194)

Haemoparasitic Infections in Cattle from a Trypanosoma brucei Rhodesiense Sleeping Sickness Endemic District of Eastern Uganda [PDF]

open access: yesTropical Medicine and Infectious Disease, 2020
We carried out a baseline survey of cattle in Kaberamaido district, in the context of controlling the domestic animal reservoir of Trypanosoma brucei rhodesiense human African trypanosomiasis (rHAT) towards elimination.
Enock Matovu   +5 more
doaj   +2 more sources

Target product profile: diagnostic test for <i>Trypanosoma brucei rhodesiense</i>. [PDF]

open access: yesBull World Health Organ, 2023
Rhodesiense human African trypanosomiasis is a lethal parasitic infection caused by Trypanosoma brucei rhodesiense and transmitted by tsetse flies in eastern and southern Africa. It accounts for around 5% of all cases of human African trypanosomiasis.
Priotto G   +14 more
europepmc   +3 more sources

The system of genetic exchange in Trypanosoma brucei and other trypanosomatids [PDF]

open access: yes, 2007
In this chapter, we discuss our current understanding of the systems of genetic exchange in trypanosomatids and the im-pact the recent genome projects have had on this area of research.
Turner, C.M.R., Tait, A., MacLeod, A.
core   +8 more sources

Therapeutic Strategies against Leishmania and Trypanosoma

open access: yesPathogens, 2023
Human African trypanosomiasis (also known as sleeping sickness, with Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense as etiological agents), American trypanosomiasis (also known as Chagas disease, with Trypanosoma cruzi as the etiological
André L. S. Santos   +5 more
doaj   +1 more source

Comparative genomics of drug resistance in Trypanosoma brucei rhodesiense. [PDF]

open access: yesCell Mol Life Sci, 2016
Trypanosoma brucei rhodesiense is one of the causative agents of human sleeping sickness, a fatal disease that is transmitted by tsetse flies and restricted to Sub-Saharan Africa. Here we investigate two independent lines of T. b. rhodesiense that have been selected with the drugs melarsoprol and pentamidine over the course of 2 years, until they ...
Graf FE   +13 more
europepmc   +8 more sources

Epidemiology of Trypanosomiasis in Wildlife—Implications for Humans at the Wildlife Interface in Africa

open access: yesFrontiers in Veterinary Science, 2021
While both human and animal trypanosomiasis continue to present as major human and animal public health constraints globally, detailed analyses of trypanosome wildlife reservoir hosts remain sparse.
Keneth Iceland Kasozi   +23 more
doaj   +1 more source

Tracking autophagy during proliferation and differentiation of Trypanosoma brucei [PDF]

open access: yes, 2014
Autophagy is a lysosome-dependent degradation mechanism that sequesters target cargo into autophagosomal vesicles. The Trypanosoma brucei genome contains apparent orthologues of several autophagy-related proteins including an ATG8 family. These ubiquitin-
Mottram, Jeremy   +3 more
core   +5 more sources

Recommendations for control of East African sleeping sickness in Uganda

open access: yesJournal of Global Infectious Diseases, 2010
East African sleeping sickness, caused by Trypanosoma brucei rhodesiense, is prominent in Uganda and poses a serious public health challenge in the region.
Simon Kotlyar
doaj   +3 more sources

Whole-Genome Sequencing of Trypanosoma brucei Reveals Introgression between Subspecies That Is Associated with Virulence

open access: yesmBio, 2013
Human African trypanosomiasis is caused by two subspecies of Trypanosoma brucei. Trypanosoma brucei rhodesiense is found in East Africa and frequently causes acute disease, while Trypanosoma brucei gambiense is found in West Africa and is associated with
Ian Goodhead   +10 more
doaj   +1 more source

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