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Human African trypanosomiasis (sleeping sickness) occurs in sub-Saharan Africa. It is caused by the protozoan parasite Trypanosoma brucei, transmitted by tsetse flies. Almost all cases are due to Trypanosoma brucei gambiense, which is indigenous to west and central Africa.
Brun, R. +3 more
openaire +5 more sources
Epidemiology of human African trypanosomiasis
Jose R Franco,1 Pere P Simarro,1 Abdoulaye Diarra,2 Jean G Jannin1 1World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland; 2World Health Organization, Inter Country Support ...
Franco JR +3 more
doaj +1 more source
African trypanosomiasis in travelers returning to the United Kingdom. [PDF]
Two returning safari tourists with African trypanosomiasis were admitted to the Hospital for Tropical Diseases, London, in a 3-day period, compared with six cases in the previous 14 years.
Bailey, J Wendi +17 more
core +1 more source
Identification of sVSG117 as an immunodiagnostic antigen and evaluation of a dual-antigen lateral flow test for the diagnosis of human african trypanosomiasis [PDF]
The diagnosis of human African trypanosomiasis (HAT) caused by Trypanosoma brucei gambiense relies mainly on the Card Agglutination Test for Trypanosomiasis (CATT). There is no immunodiagnostic for HAT caused by T. b. rhodesiense.
Sastry Lalitha +20 more
core +1 more source
Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis [PDF]
Human African trypanosomiasis, or sleeping sickness, is caused by the protozoan parasites <i>Trypanosoma brucei rhodesiense</i> or <i>Trypanosoma brucei gambiense</i>, and is a major cause of systemic and neurological disability ...
Barrett, M.P. +4 more
core +1 more source
Background Tsetse flies are the cyclical vectors of both human and animal diseases. Kenya’s commitment to eradicate tsetse and trypanosomiasis dates to the 1980s through various control approaches which were spearheaded by the African Union.
Ferdinard Adungo +3 more
doaj +1 more source
Towards the Atlas of human African trypanosomiasis [PDF]
Background Updated, accurate and comprehensive information on the distribution of human African trypanosomiasis (HAT), also known as sleeping sickness, is critically important to plan and monitor control activities.
Cecchi Giuliano +28 more
core +1 more source
Plant Terpenoids as Hit Compounds against Trypanosomiasis
Human African trypanosomiasis (sleeping sickness) and American trypanosomiasis (Chagas disease) are vector-borne neglected tropical diseases, caused by the protozoan parasites Trypanosoma brucei and Trypanosoma cruzi, respectively.
Raquel Durão +4 more
doaj +1 more source
Focus–specific clinical profiles in human African trypanosomiasis caused by Trypanosoma brucei rhodesiense [PDF]
<p><b>Background:</b> Diverse clinical features have been reported in human African trypanosomiasis (HAT) foci caused by <i>Trypanosoma brucei rhodesiense</i> (<i>T.b.rhodesiense</i>) giving rise to the ...
Odiit, Martin +18 more
core +1 more source
Background: African trypanocide resistance is an emerging public health emergency whose control requires a revisit on farmer’s knowledge, attitudes, and practices in developing countries.
Keneth Iceland Kasozi +5 more
doaj +1 more source

