Results 11 to 20 of about 12,832 (181)
The history of African trypanosomiasis [PDF]
Parasites & Vectors, 2008 The prehistory of African trypanosomiasis indicates that the disease may have been an important selective factor in the evolution of hominids. Ancient history and medieval history reveal that African trypanosomiasis affected the lives of people living in
Steverding Dietmar
doaj +4 more sources
Control of Human African Trypanosomiasis in the Nola-Bilolo Focus, Central African Republic, 2020–2024: Outcome of Capacity Building, Improved Diagnosis and Treatment [PDF]
Journal of Parasitology ResearchThis study is aimed at evaluating the inclusion of miniature anion-exchange centrifugation technique (mAECT) in the diagnosis and fexinidazole as treatment of gHAT in Central African Republic (CAR) after capacity building.
Pierre-Marie Douzima +4 more
doaj +2 more sources
The household burden of sleeping sickness: out-of-pocket costs for diagnosis and treatment [PDF]
BMJ Global HealthPurpose This study estimated out-of-pocket (OOP) expenses associated with Human African Trypanosomiasis (HAT) care in the Democratic Republic of the Congo (DRC) and explored how they influenced care-seeking behaviour and participation in HAT control ...
Fabrizio Tediosi +7 more
doaj +2 more sources
African Trypanosomiasis Gambiense, Italy
Emerging Infectious Diseases, 2005 African trypanosomiasis caused by Trypanosoma brucei gambiense has not been reported in Italy. We report 2 cases diagnosed in the summer of 2004. Theses cases suggest an increased risk for expatriates working in trypanosomiasis-endemic countries.
Zeno Bisoffi +7 more
doaj +6 more sources
A Role for Janus Cyclohexyl Ring Motifs in Medicinal Chemistry. Incorporation Into G-Quadruplex Ligands and Anti-Trypanosoma brucei Activity. [PDF]
ChembiochemNaphthalene diimide (NDI) cores with peripheral fluorocyclohexyl ring systems are explored binding to G‐quadruplex DNA and were also assayed against the Trypanosoma brucei parasite. The most active compound of the series displayed nanomolar activity and suggested electrostatic interactions between the polarized cyclohexane and G‐Quad DNA.
Stewart JM +7 more
europepmc +2 more sources
The Pathogenesis of African Trypanosomiasis
Annual Review of Pathology: Mechanisms of Disease, 2023 African trypanosomes are bloodstream protozoan parasites that infect mammals including humans, where they cause sleeping sickness. Long-lasting infection is required to favor parasite transmission between hosts. Therefore, trypanosomes have developed strategies to continuously escape innate and adaptive responses of the immune system, while also ...
Pays, Etienne +2 more
openaire +4 more sources
Evaluating paratransgenesis as a potential control strategy for African trypanosomiasis. [PDF]
PLoS Neglected Tropical Diseases, 2013 Genetic-modification strategies are currently being developed to reduce the transmission of vector-borne diseases, including African trypanosomiasis. For tsetse, the vector of African trypanosomiasis, a paratransgenic strategy is being considered: this ...
Jan Medlock +4 more
doaj +1 more source
BMC Pediatrics, 2022 Background In South Sudan, sleeping sickness is a frequent condition caused by human African trypanosomiasis. There are two stages that are well-known.
Etedal Ahmed A. Ibrahim +4 more
doaj +1 more source
BMC Public Health, 2023 Background There have been many prediction studies for imported infectious diseases, employing air-travel volume or the importation risk (IR) index, which is the product of travel-volume and disease burden in the source countries, as major predictors ...
Kyung-Duk Min +4 more
doaj +1 more source
Tropical Medicine and Infectious Disease, 2020 Tsetse transmitted trypanosomiasis is a fatal disease commonly known as Nagana in cattle and sleeping sickness in humans. The disease threatens food security and has severe economic impact in Africa including most parts of Zambia.
Gloria M. Mulenga +5 more
doaj +1 more source