Results 21 to 30 of about 26,119 (196)

Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection [PDF]

, 2020
Bovine African Trypanosomosis is an infectious parasitic disease affecting livestock productivity and thereby impairing the economic development of Sub-Saharan Africa. The most important trypanosome species implicated is T.
Brys, Lea, De Baetselier, Patrick, De Trez, Carl, Korf, Hannelie, Magez, Stefan, Stijlemans, Benoit, Van Ginderachter, Jo A   +6 more
core   +1 more source

Human African trypanosomiasis : the current situation in endemic regions and the risks for non-endemic regions from imported cases [PDF]

, 2020
Human African trypanosomiasis (HAT) is caused by Trypanosoma brucei gambiense and T. b. rhodesiense and caused devastating epidemics during the 20th century. Due to effective control programs implemented in the last two decades, the number of reported
Gao, J-M, Hide, G, Lai, D-H, Lun, Z-R, Qian, Z-Y, Wu, Z-D   +5 more
core   +2 more sources

Tsetse distribution, trypanosome infection rates, and small-holder livestock producers’ capacity enhancement for sustainable tsetse and trypanosomiasis control in Busia, Kenya

Tropical Medicine and Health, 2020
Background Tsetse flies are the cyclical vectors of both human and animal diseases. Kenya’s commitment to eradicate tsetse and trypanosomiasis dates to the 1980s through various control approaches which were spearheaded by the African Union.
Ferdinard Adungo, Tom Mokaya, Olipher Makwaga, Matilu Mwau   +3 more
doaj   +1 more source

Human African trypanosomiasis

The Lancet, 2017
Human African trypanosomiasis (sleeping sickness) is a parasitic infection that almost invariably progresses to death unless treated. Human African trypanosomiasis caused devastating epidemics during the 20th century. Thanks to sustained and coordinated efforts over the past 15 years, the number of reported cases has fallen to an historically low level.
Buscher, P., Cecchi, G., /Jamonneau, Vincent, Priotto, G.   +3 more
openaire   +6 more sources

African Trypanosomes undermine humoral responses and vaccine development : link with inflammatory responses? [PDF]

, 2017
African trypanosomosis is a debilitating disease of great medical and socioeconomical importance. It is caused by strictly extracellular protozoan parasites capable of infecting all vertebrate classes including human, livestock, and game animals.
Achcar, Alampour-Rajabi, Alirol, Allman, Authie, Authié, Auty, Baker, Balber, Banks, Barry, Barry, Berthier, Beschin, Beschin, Blom-Potar, Bockstal, Bockstal, Boller, Bonnet, Borst, Bosschaerts, Boulange, Bouyer, Brun, Brun, Bucheton, Calandra, Capewell, Chamond, Claes, Cnops, Cnops, Cnops, Cnops, Coller, Dagenais, Darji, De Muylder, De Trez, Delafosse, Delespaux, Desquesnes, Devine, Disease, Drennan, Dubois, Duszenko, Engstler, Fenn, Ferrante, Field, Figarella, Franco, Frenkel, Gilbert, Giordani, Gomez-Rodriguez, Graham, Graham, Haanstra, Hall, Hasker, Hemphill, Holland, Holland, Holt, Jamonneau, Jarvinen, Jones, Keitany, Kennedy, Kennedy, Klasen, Kondo, Kroubi, Kuriakose, La Greca, La Greca, Lalmanach, Lanca, Lebien, Lejon, Lejon, Leng, MacGregor, MacGregor, MacLean, MacLean, Magez, Magez, Magez, Mansfield, McGettrick, Mekori, Millar, Mogk, Mony, Morrison, Morrison, Morrison, Mulindwa, Mårtensson, Naessens, Naula, Ng, Nutt, Obishakin, Odongo, Onyilagha, Ooi, Ooi, Osório, O’Gorman, Paulnock, Pays, Peacock, Priotto, Radwanska, Radwanska, Reth, Rico, Rodgers, Rotureau, Ruiz-Postigo, Salmon, Schwede, Schwede, Seed, Sharpe, Sileghem, Sileghem, Simarro, Simarro, Simarro, Stijlemans, Stijlemans, Stijlemans, Stijlemans, Stijlemans, Stijlemans, Stijlemans, Swallow, Takeya, Taylor, Taylor, Taylor, Telleria, Tiberti, Trindade, Unciti-Broceta, Uzonna, Uzonna, Van Den Abbeele, Vassella, Welburn, Welburn, Wellde, Wenzler, Willert, Yaro   +160 more
core   +1 more source

Plant Terpenoids as Hit Compounds against Trypanosomiasis

Pharmaceuticals, 2022
Human African trypanosomiasis (sleeping sickness) and American trypanosomiasis (Chagas disease) are vector-borne neglected tropical diseases, caused by the protozoan parasites Trypanosoma brucei and Trypanosoma cruzi, respectively.
Raquel Durão, Cátia Ramalhete, Ana Margarida Madureira, Eduarda Mendes, Noélia Duarte   +4 more
doaj   +1 more source

Systematic Review and Meta-Analysis on Knowledge Attitude and Practices on African Animal Trypanocide Resistance

Tropical Medicine and Infectious Disease, 2022
Background: African trypanocide resistance is an emerging public health emergency whose control requires a revisit on farmer’s knowledge, attitudes, and practices in developing countries.
Keneth Iceland Kasozi, Ewan Thomas MacLeod, Charles Waiswa, Michael Mahero, Ibrahim Ntulume, Susan Christina Welburn   +5 more
doaj   +1 more source

Breeding of African sheep reared under low-input/output smallholder production systems for trypanotolerance [PDF]

Veterinary World, 2022
Trypanosomiasis is a disease caused by unicellular protozoan parasites. Small ruminants succumb to trypanosomiasis in areas of high tsetse fly challenge, resulting in serious economic loss often to farmers in low-input smallholder systems.
Dikeledi P. Malatji
doaj   +1 more source

Effectiveness of a 10-day melarsoprol schedule for the treatment of late-stage human African trypanosomiasis: confirmation from a multinational study (IMPAMEL II). [PDF]

, 2005
BACKGROUND: Treatment of late-stage human African trypanosomiasis (HAT) with melarsoprol can be improved by shortening the regimen. A previous trial demonstrated the safety and efficacy of a 10-day treatment schedule.
Asumu, P, Bilenge, C M M, Burri, C, Chappuis, F, Doua, F, Josenando, T, Manthelot, C R, Nangouma, A, Richer, M, Schmid, C, Simarro, P   +10 more
core   +2 more sources

APOL1 renal risk variants have contrasting resistance and susceptibility associations with African trypanosomiasis

eLife, 2017
Reduced susceptibility to infectious disease can increase the frequency of otherwise deleterious alleles. In populations of African ancestry, two apolipoprotein-L1 (APOL1) variants with a recessive kidney disease risk, named G1 and G2, occur at high ...
Anneli Cooper, Hamidou Ilboudo, V Pius Alibu, Sophie Ravel, John Enyaru, William Weir, Harry Noyes, Paul Capewell, Mamadou Camara, Jacqueline Milet, Vincent Jamonneau, Oumou Camara, Enock Matovu, Bruno Bucheton, Annette MacLeod   +14 more
doaj   +1 more source