Results 51 to 60 of about 28,049 (192)

Human African trypanosomiasis

, 2013
Human African trypanosomiasis or sleeping sickness is a neglected tropical disease that affects populations in sub-Saharan Africa. The disease is caused by infection with the gambiense and rhodesiense subspecies of the extracellular parasite Trypanosoma brucei, and is transmitted to humans by bites of infected tsetse flies.
Lejon, Veerle, Bentivoglio, M., Franco, J.R.   +2 more
openaire   +3 more sources

African trypanosomiasis

, 2010
African trypanosomes continue to present major public and livestock health problems in sub-Saharan African, typically in rural communities with limited access to diagnosis and treatment. Over the past 50 years, a tractable set of laboratory models for this infection has led to an appreciation of the immunological, cellular and molecular subtleties of ...
Sternberg, Jeremy M, Black, Samuel J, Stefan, Magez   +2 more
  +4 more sources

Challenges facing the elimination of sleeping sickness in west and central Africa: sustainable control of animal trypanosomiasis as an indispensable approach to achieve the goal

Parasites & Vectors, 2015
African trypanosomiases are infectious diseases caused by trypanosomes. African animal trypanosomiasis (AAT) remains an important threat for livestock production in some affected areas whereas human African trypanosomiasis (HAT) is targeted for ...
Gustave Simo, Jean Baptiste Rayaisse
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, Volume 600, Issue 5, Page 591-611, March 2026.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

MIF contributes to Trypanosoma brucei associated immunopathogenicity development [PDF]

, 2014
African trypanosomiasis is a chronic debilitating disease affecting the health and economic well-being of many people in developing countries. The pathogenicity associated with this disease involves a persistent inflammatory response, whereby M1-type ...
Beschin, Alain, Brys, Lea, Bucala, Richard, Caljon, Guy, De Baetselier, Patrick, Leng, Lin, Raes, Geert, Sparkes, Amanda, Stijlemans, Benoit, Van Den Abbeele, Jan, Van Ginderachter, Jo A, Vansintjan, Liese   +11 more
core   +4 more sources

Reemergence of Human African Trypanosomiasis Caused by Trypanosoma brucei rhodesiense, Ethiopia

Emerging Infectious Diseases
We report 4 cases of human African trypanosomiasis that occurred in Ethiopia in 2022, thirty years after the last previously reported case in the country. Two of 4 patients died before medicine became available.
Adugna Abera, Tihitina Mamecha, Ebise Abose, Belachew Bokicho, Agune Ashole, Tesfahun Bishaw, Abinet Mariyo, Buzayehu Bogale, Haileyesus Terefe, Henok Tadesse, Mahlet Belachew, Hailemariam Difabachew, Araya Eukubay, Solomon Kinde, Abraham Ali, Feyesa Regasa, Fikre Seife, Zeyede Kebede, Mesfin Wossen, Getachew Tollera, Mesay Hailu, Nigus Manaye, Nick Van Reet, Gerardo Priotto, Johan van Griensven, Myrthe Pareyn, Geremew Tasew   +26 more
doaj   +1 more source

Comparative clinico-haematological analysis in young Zebu cattle experimentally infected with Trypanosoma vivax isolates from tsetse infested and non-tsetse infested areas of Northwest Ethiopia [PDF]

, 2015
Background: Ethiopia, particularly in the Northwest region, is affected by both tsetse and non-tsetse fly transmitted trypanosomosis, with significant impact on livestock productivity. The aim of this study was to determine and compare clinical findings
Abebe, Getachew, Barry, J. David, Bezie, Melkamu, Dagnachew, Shimelis, Goddeeris, Bruno M., Terefe, Getachew   +5 more
core   +2 more sources

Estimation of Demand and Supply Balance of Livestock Feed in Haru District, Western Ethiopia

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
The feed supply showed a deficit (negative balance) of 43.6% and 30% DM, 66.1% and 61.2% DCP and 27.7% and 7.3% ME in ML and LL AEZs, respectively. ABSTRACT Background Ethiopia has the largest livestock population in Africa, making livestock crucial for food security and rural livelihoods in the country.
Tamene Bayissa, Belay Duguma, Kassahun Dessalegn   +2 more
wiley   +1 more source

Molecular epidemiology of African sleeping sickness [PDF]

, 2009
Human sleeping sickness in Africa, caused by Trypanosoma brucei spp. raises a number of questions. Despite the widespread distribution of the tsetse vectors and animal trypanosomiasis, human disease is only found in discrete foci which periodically give ...
A. TAIT, G. HIDE, Gibson, Hide, Mehlitz, Morrison   +5 more
core   +2 more sources

Trypanocidal and leishmanicidal activity of six limonoids [PDF]

, 2020
Six limonoids [kotschyienone A and B (1, 2), 7-deacetylgedunin (3), 7-deacetyl-7-oxogedunin (4), andirobin (5) and methyl angolensate (6)] were investigated for their trypanocidal and leishmanicidal activities using bloodstream forms of Trypanosoma ...
A-E Hay, AC Ivens, Bathelemy Ngameni, D Steverding, D Steverding, D Steverding, DAH Taylor, Dietmar Steverding, Evelyne Ollivier, G. Richard Stephenson, Gabriel N. Folefoc, GM Cragg, H Hirumi, J Mikus, K Merschjohann, Kevin M. Tyler, KM Ahua, Lazare S. Sidjui, LS Sidjui, PM Cheuka, S Nwaka, SE Atawodi, SJ Collins, T Baltz, Thomas E. Storr, Valérie Mahiou-Leddet, W Huber, W Ravangpai, Y-B Cheng, Éden Ramalho Ferreira, ÉR Ferreira   +30 more
core   +3 more sources